Edoxaban, a factor Xa inhibitor, is supplied as edoxaban tosylate monohydrate. The chemical name is -(5-Chloropyridin-2-yl)–[(1,2,4)-4-(-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-]pyridine-2-carboxamido)cyclohexyl] oxamide mono (4-methylbenzenesulfonate) monohydrate. Edoxaban tosylate monohydrate has the empirical formula CHClNOS•CHOS•HO representing a molecular weight of 738.27. The chemical structure of edoxaban tosylate… Continue Reading
SOOLANTRA (ivermectin) cream, 1% is a white to pale yellow hydrophilic cream. Each gram of SOOLANTRA cream contains 10 mg of ivermectin. It is intended for topical use. Ivermectin is a semi-synthetic derivative isolated from the fermentation of Streptomyces avermitilis… Continue Reading
The active ingredient in SOLOSEC Oral Granules is secnidazole (also named 1-(2- hydroxypropyl)-2-methyl-5-nitroimidazole and 1-(2-methyl-5-nitro-1-imidazol-1-yl) propan-2- ol), a nitroimidazole antimicrobial. The molecular formula of secnidazole is CHNO, the molecular weight is 185.18 and the chemical structure is: Figure 1: Structure… Continue Reading
The concentrated sodium iodide I 131 solution is available in strengths ranging from 18.5 – 129.5 GBq/mL (500 – 3500 mCi/mL) and is used for the preparation of sodium iodide I 131 capsules or sodium iodide I 131 solution of… Continue Reading
SURVANTA (beractant) Intratracheal Suspension is a sterile, non-pyrogenic pulmonary surfactant intended for intratracheal use only. It is a natural bovine lung extract containing phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins to which colfosceril palmitate (dipalmitoylphosphatidylcholine), palmitic acid, and tripalmitin… Continue Reading
SSKI (potassium iodide oral solution, USP) is a saturated solution of potassium iodide containing 1 gram of potassium iodide per mL.
SPORANOXis the brand name for itraconazole, an azole antifungal agent. Itraconazole is a 1:1:1:1 racemic mixture of four diastereomers (two enantiomeric pairs), each possessing three chiral centers. It may be represented by the following structural formula and nomenclature: (±)-1-[(*)–butyl]-4-[-[4-[-[[(2*,4*)-2-(2,4-dichlorophenyl)-2-(1-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-Δ-1,2,4-triazolin-5-one mixture… Continue Reading
SYLATRON, peginterferon alfa-2b, is a covalent conjugate of recombinant alfa-2b interferon with monomethoxy polyethylene glycol (PEG). The average molecular weight of the PEG portion of the molecule is 12,000 daltons. The average molecular weight of the SYLATRON molecule is approximately… Continue Reading
Each sustained-release tablet for oral administration contains: Hyoscyamine Sulfate . . . 0.375 mg Hyoscyamine sulfate is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids. Hyoscyamine sulfate is Benzeneacetic acid, α-(hydroxymethyl)-, 8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)- ]-, sulfate (2:1), dihydrate.… Continue Reading
Each tablet for oral administration contains: Hyoscyamine Sulfate . . . 0.125 mg Hyoscyamine sulfate is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids. Hyoscyamine sulfate is Benzeneacetic acid, α-(hydroxymethyl)-, 8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)- ]-, sulfate (2:1), dihydrate. (C… Continue Reading
