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Norgestimate and Ethinyl Estradiol

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Overview

What is Norgestimate and Ethinyl Estradiol?

Each of the following products is a combination oral contraceptive containing the progestational compound norgestimate and the estrogenic compound ethinyl estradiol. Norgestimate is designated as (18,19-Dinor-17-pregn-4-en-20-yn-3-one,17-(acetyloxy)-13-ethyl-, oxime,(17α) - (+)-) and ethinyl estradiol is designated as (19-nor-17α-pregna,1,3,5(10)-trien-20-yne-3,17-diol).



What does Norgestimate and Ethinyl Estradiol look like?



What are the available doses of Norgestimate and Ethinyl Estradiol?

Norgestimate and ethinyl estradiol tablets consist of 28 round, biconvex, coated tablets in the following order ():

What should I talk to my health care provider before I take Norgestimate and Ethinyl Estradiol?

Nursing mothers: Not recommended; can decrease milk production. ()

How should I use Norgestimate and Ethinyl Estradiol?

Norgestimate and ethinyl estradiol tablets USP are estrogen/progestin COCs, indicated for use by women to prevent pregnancy. ()

Norgestimate and ethinyl estradiol tablets USP are dispensed in a wallet Norgestimate and ethinyl estradiol tablets USP may be started using either a Day 1 start or a Sunday start (see Table 1). For the first cycle of a Sunday Start regimen, an additional method of contraception should be used until after the first 7 consecutive days of administration.


What interacts with Norgestimate and Ethinyl Estradiol?

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What are the warnings of Norgestimate and Ethinyl Estradiol?

Sorry No Records found


What are the precautions of Norgestimate and Ethinyl Estradiol?

Sorry No Records found


What are the side effects of Norgestimate and Ethinyl Estradiol?

Sorry No records found


What should I look out for while using Norgestimate and Ethinyl Estradiol?

Do not prescribe norgestimate and ethinyl estradiol tablets to women who are known to have the following conditions:

ID343

Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs are contraindicated in women who are over 35 years of age and smoke


What might happen if I take too much Norgestimate and Ethinyl Estradiol?

There have been no reports of serious ill effects from overdosage of oral contraceptives, including ingestion by children. Overdosage may cause withdrawal bleeding in females and nausea.


How should I store and handle Norgestimate and Ethinyl Estradiol?

Store EVZIO in the outer case provided.Store at controlled room temperature 15°C to 25°C (59°F to 77°F) excursions permitted between 4°C and 40°C (between 39°F and 104°F).Before using, check to make sure the solution in the auto-injector is not discolored. Replace EVZIO if the solution is discolored or contains a precipitate.Store EVZIO in the outer case provided.Store at controlled room temperature 15°C to 25°C (59°F to 77°F) excursions permitted between 4°C and 40°C (between 39°F and 104°F).Before using, check to make sure the solution in the auto-injector is not discolored. Replace EVZIO if the solution is discolored or contains a precipitate.Store EVZIO in the outer case provided.Store at controlled room temperature 15°C to 25°C (59°F to 77°F) excursions permitted between 4°C and 40°C (between 39°F and 104°F).Before using, check to make sure the solution in the auto-injector is not discolored. Replace EVZIO if the solution is discolored or contains a precipitate.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30                              NDC 68788-6321-3Bottles of 60                              NDC 68788-6321-6Bottles of 90                              NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30                              NDC 68788-6321-3Bottles of 60                              NDC 68788-6321-6Bottles of 90                              NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30                              NDC 68788-6321-3Bottles of 60                              NDC 68788-6321-6Bottles of 90                              NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30                              NDC 68788-6321-3Bottles of 60                              NDC 68788-6321-6Bottles of 90                              NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

COCs lower the risk of becoming pregnant primarily by suppressing ovulation. Other possible mechanisms may include cervical mucus changes that inhibit sperm penetration and endometrial changes that reduce the likelihood of implantation.

Non-Clinical Toxicology
Do not prescribe norgestimate and ethinyl estradiol tablets to women who are known to have the following conditions:

ID343

Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs are contraindicated in women who are over 35 years of age and smoke

Thromboembolic Disorders and Other Vascular Problems

Liver disease

High blood pressure

Carbohydrate and lipid metabolic effects

Headache

Bleeding Irregularities and Amenorrhea

The following serious adverse reactions with the use of COCs are discussed elsewhere in labeling:

Adverse reactions commonly reported by COC users are:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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