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oxybutynin

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Overview

What is oxybutynin?

Oxybutynin chloride extended-release tablets  are an antispasmodic, muscarinic antagonist. Each oxybutynin chloride Extended-release tablets contains 5 mg, 10 mg, or 15 mg of oxybutynin chloride USP, formulated as a once-a-day controlled-release tablet for oral administration. Oxybutynin chloride is administered as a racemate of R-and S-enantiomers.

Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate hydrochloride. The empirical formula of oxybutynin chloride is CHNO•HCl.

Its structural formula is:

Oxybutynin chloride, USP is a white crystalline, practically odorless powder with a molecular weight of 393.95. It is freely soluble in water and in alcohol, very soluble in methanol and in chloroform, soluble in acetone, slightly soluble in ether and very slightly soluble in hexane.

Oxybutynin chloride extended-release tablet also contains the following inactive ingredients: alginic acid, hydrogenated castor oil, hypromellose, lactose monohydrate, magnesium stearate, methacrylic acid copolymer dispersion, microcrystalline cellulose, povidone, talc and triethyl citrate.

The USP Dissolution Test is pending.

System Components and Performance

Oxybutynin chloride extended-release tablet uses an enteric coated hydrophilic hydrogel matrix to deliver oxybutynin chloride at controlled rate over approximately 24 hours by diffusion mechanism. The system comprises of a core, which contains the drug, rate controlling hydrogel and other excipients. The core is surrounded by a partially or complete pH dependent membrane. Hence, when the drug reaches the acidic medium, in stomach minimal drug release will occur and when it reaches an environment of pH 5.5 and above, the outer membrane will be dissolved exposing the inner core. This inner core will partially hydrate to form a gel layer and the drug release will occur via diffusion mechanism from a gel layer and subsequently through gel erosion.



What does oxybutynin look like?



What are the available doses of oxybutynin?

Oxybutynin chloride extended-release tablets are available as 5 mg, 10 mg and 15 mg tablets for oral use:

Oxybutynin chloride extended-release tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side.

Oxybutynin chloride extended-release tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side.

Oxybutynin chloride extended-release tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side.

What should I talk to my health care provider before I take oxybutynin?

How should I use oxybutynin?

Oxybutynin chloride extended release tablets must be swallowed whole with the aid of liquids, and must not be chewed, divided, or crushed.

Oxybutynin chloride extended release tablets may be administered with or without food.


What interacts with oxybutynin?

Sorry No Records found


What are the warnings of oxybutynin?

Sorry No Records found


What are the precautions of oxybutynin?

Sorry No Records found


What are the side effects of oxybutynin?

Sorry No records found


What should I look out for while using oxybutynin?

Urinary retention ()

Gastric Retention ()

Uncontrolled narrow angle glaucoma ()

Known hypersensitivity to oxybutynin chloride or any component of oxybutynin chloride extended-release tablets ()


What might happen if I take too much oxybutynin?

The continuous release of oxybutynin from oxybutynin chloride extended-release tablets should be considered in the treatment of overdosage. Patients should be monitored for at least 24 hours. Treatment should be symptomatic and supportive. Activated charcoal as well as a cathartic may be administered.

Overdosage with oxybutynin chloride has been associated with anticholinergic effects including central nervous system excitation, flushing, fever, dehydration, cardiac arrhythmia, vomiting, and urinary retention.

Ingestion of 100 mg oxybutynin chloride in association with alcohol has been reported in a 13 year old boy who experienced memory loss, and a 34 year old woman who developed stupor, followed by disorientation and agitation on awakening, dilated pupils, dry skin, cardiac arrhythmia, and retention of urine. Both patients fully recovered with symptomatic treatment.


How should I store and handle oxybutynin?

Oxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 5 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "255" and plain on other side and are supplied as follows:NDC 70771-1086-6 in bottle of 30 tabletsNDC 70771-1086-6 in bottle of 60 tabletsNDC 70771-1086-9 in bottle of 90 tabletsNDC 70771-1086-1 in bottle of 100 tabletsNDC 70771-1086-5 in bottle of 500 tabletsNDC 70771-1086-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 10 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "256" and plain on other side and are supplied as follows:NDC 70771-1087-3 in bottle of 30 tabletsNDC 70771-1087-6 in bottle of 60 tabletsNDC 70771-1087-9 in bottle of 90 tabletsNDC 70771-1087-1 in bottle of 100 tabletsNDC 70771-1087-5 in bottle of 500 tabletsNDC 70771-1087-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tabletsOxybutynin Chloride Extended-release Tablets, 15 mg are white to off-white, round, beveled-edged, biconvex, coated-tablets debossed on one side with "257" and plain on other side and are supplied as follows:NDC 70771-1088-3 in bottle of 30 tabletsNDC 70771-1088-6 in bottle of 60 tabletsNDC 70771-1088-9 in bottle of 90 tabletsNDC 70771-1088-1 in bottle of 100 tabletsNDC 70771-1088-5 in bottle of 500 tabletsNDC 70771-1088-4 in unit-dose blister cartons of 100 (10 x 10) unit-dose tablets


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Oxybutynin relaxes bladder smooth muscle. Oxybutynin chloride exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects).

Antimuscarinic activity resides predominantly in the R-isomer. A metabolite, desethyloxybutynin, has pharmacological activity similar to that of oxybutynin in studies.

Non-Clinical Toxicology
Urinary retention ()

Gastric Retention ()

Uncontrolled narrow angle glaucoma ()

Known hypersensitivity to oxybutynin chloride or any component of oxybutynin chloride extended-release tablets ()

Large doses of naloxone are required to antagonize buprenorphine since the latter has a long duration of action due to its slow rate of binding and subsequent slow dissociation from the opioid receptor. Buprenorphine antagonism is characterized by a gradual onset of the reversal effects and a decreased duration of action of the normally prolonged respiratory depression. The barbiturate methohexital appears to block the acute onset of withdrawal symptoms induced by naloxone in opiate addicts.

Angioedema of the face, lips, tongue and/or larynx has been reported with oxybutynin. In some cases, angioedema occurred after the first dose. Angioedema associated with upper airway swelling may be life-threatening. If involvement of the tongue, hypopharynx, or larynx occurs, oxybutynin should be promptly discontinued and appropriate therapy and/or measures necessary to ensure a patent airway should be promptly provided.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).