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OXYCODONE HCL

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Overview

What is OXYCODONE HCL?



What does OXYCODONE HCL look like?



What are the available doses of OXYCODONE HCL?

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What should I talk to my health care provider before I take OXYCODONE HCL?

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How should I use OXYCODONE HCL?


What interacts with OXYCODONE HCL?

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What are the warnings of OXYCODONE HCL?

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What are the precautions of OXYCODONE HCL?

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What are the side effects of OXYCODONE HCL?

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What should I look out for while using OXYCODONE HCL?


What might happen if I take too much OXYCODONE HCL?


How should I store and handle OXYCODONE HCL?

SERNIVO Spray is a slightly thickened, white to off-white, non-sterile emulsion supplied in high density polyethylene bottles with a heat induction seal lined polypropylene cap. The drug is supplied in the following volumes: Store at controlled room temperature of 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F) .Each unit is co-packaged with a manual spray pump for installation by the pharmacist prior to dispensing.SERNIVO Spray is a slightly thickened, white to off-white, non-sterile emulsion supplied in high density polyethylene bottles with a heat induction seal lined polypropylene cap. The drug is supplied in the following volumes: Store at controlled room temperature of 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F) .Each unit is co-packaged with a manual spray pump for installation by the pharmacist prior to dispensing.SERNIVO Spray is a slightly thickened, white to off-white, non-sterile emulsion supplied in high density polyethylene bottles with a heat induction seal lined polypropylene cap. The drug is supplied in the following volumes: Store at controlled room temperature of 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F) .Each unit is co-packaged with a manual spray pump for installation by the pharmacist prior to dispensing.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.Caffeine citrate injection is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution.Caffeine citrate injection vials contain 3 mL solution at a concentration of caffeine citrate 20 mg/mL (60 mg/vial) equivalent to caffeine base 10 mg/mL (30 mg/vial).Caffeine Citrate Injection, USPNDC 0517-0020-10                3 mL Single Dose Vial                Packages of 10NDC 0517-0020-25                3 mL Single Dose Vial                Packages of 25Preservative Free. For single use only. Discard unused portion. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). [see USP Controlled Room Temperature].IN0020Rev. 09/11AMERICANREGENT, INC.


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Non-Clinical Toxicology
Cytochrome P450 1A2 (CYP1A2) is known to be the major enzyme involved in the metabolism of caffeine. Therefore, caffeine has the potential to interact with drugs that are substrates for CYP1A2, inhibit CYP1A2, or induce CYP1A2.

Few data exist on drug interactions with caffeine in preterm neonates. Based on adult data, lower doses of caffeine may be needed following coadministration of drugs which are reported to decrease caffeine elimination (e.g., cimetidine and ketoconazole) and higher caffeine doses may be needed following coadministration of drugs that increase caffeine elimination (e.g., phenobarbital and phenytoin).

Caffeine administered concurrently with ketoprofen reduced the urine volume in four healthy volunteers. The clinical significance of this interaction in preterm neonates is not known.

Interconversion between caffeine and theophylline has been reported in preterm neonates. The concurrent use of these drugs is not recommended.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).