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POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES

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Overview

What is POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

For oral solution: Each 4 liter (4L) PEG-3350 and electrolytes for oral solution jug contains a white powder for reconstitution. PEG-3350 and electrolytes for oral solution is a combination of polyethylene glycol 3350, an osmotic laxative, and electrolytes (sodium sulfate, sodium chloride, sodium bicarbonate and potassium chloride) for oral solution.

Each 4 liter jug contains: polyethylene glycol 3350 236 g, sodium sulfate (anhydrous) 22.74 g, sodium bicarbonate 6.74 g, sodium chloride 5.86 g, potassium chloride 2.97 g. The solution is clear and colorless when reconstituted to a final volume of 4 liters with water.

Polyethylene Glycol 3350, NF

Sodium Sulfate, USP

The chemical name is Na2SO4. The average Molecular Weight is 142.04. The structural formula is:

Sodium Bicarbonate, USP

The chemical name is NaHCO3. The average Molecular Weight is 84.01. The structural formula is:

Sodium Chloride, USP

The chemical name is NaCl. The average Molecular Weight: 58.44. The structural formula is:

Na+ Cl-

Potassium Chloride, USP

The chemical name is KCl. The average Molecular Weight: 74.55. The structural formula is:

K-Cl



What does POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES look like?



What are the available doses of POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

For oral solution: One 4 liter jug with powder for reconstitution with water.

Each 4 liter jug contains: polyethylene glycol 3350 236 g, sodium sulfate (anhydrous) 22.74 g, sodium bicarbonate 6.74 g, sodium chloride 5.86 g, potassium chloride 2.97 g. When made up to 4 liters volume with water, the solution contains PEG-3350 17.6 mmol/L, sodium 125 mmol/L, sulfate 40 mmol/L, chloride 35 mmol/L, bicarbonate 20 mmol/L and potassium 10 mmol/L.

What should I talk to my health care provider before I take POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

How should I use POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

PEG-3350 and electrolytes for oral solution, USP is a combination of PEG 3350, an osmotic laxative, and electrolytes indicated for cleansing of the colon in preparation for colonoscopy and barium enema X-ray examination in adults ()

PEG-3350 and electrolytes for oral solution, supplied as a powder, must be reconstituted with water before its use; it is not for direct ingestion The 4 liter reconstituted PEG-3350 and electrolytes for oral solution solution contains: 236 grams of polyethylene glycol (PEG) 3350, 22.74 grams sodium sulfate (anhydrous), 6.74 grams of sodium bicarbonate, 5.86 grams of sodium chloride, and 2.97 grams of potassium chloride. PEG-3350 and electrolytes for oral solution is supplied with lemon flavor pack.


What interacts with POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

Sorry No Records found


What are the warnings of POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

Sorry No Records found


What are the precautions of POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

Sorry No Records found


What are the side effects of POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

Sorry No records found


What should I look out for while using POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

Gastrointestinal (GI) obstruction, ileus, or gastric retention (, )

Bowel perforation (, )

Toxic colitis or toxic megacolon ()

Known allergy or hypersensitivity to components of PEG-3350 and electrolytes for oral solution (, )


What might happen if I take too much POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

Sorry No Records found


How should I store and handle POLYETHYLENE GLYCOL-3350 AND ELECTROLYTES?

StorageStore bottles at controlled room temperature, 59° to 86°F (15° to 30°C) and dispense in tight, light-resistant containers (USP).StorageStore bottles at controlled room temperature, 59° to 86°F (15° to 30°C) and dispense in tight, light-resistant containers (USP).In powdered form, for oral administration as a solution following reconstitution. PEG-3350 and electrolytes for oral solution, USP is available in a disposable jug in powdered form containing:Disposable JugStorage:Store in sealed container at 59º to 86°F (15ºC to 30°C).  When reconstituted, keep solutionrefrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children.PEG-3350 and electrolytes for oral solution  NDC 40032-090-19In powdered form, for oral administration as a solution following reconstitution. PEG-3350 and electrolytes for oral solution, USP is available in a disposable jug in powdered form containing:Disposable JugStorage:Store in sealed container at 59º to 86°F (15ºC to 30°C).  When reconstituted, keep solutionrefrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children.PEG-3350 and electrolytes for oral solution  NDC 40032-090-19In powdered form, for oral administration as a solution following reconstitution. PEG-3350 and electrolytes for oral solution, USP is available in a disposable jug in powdered form containing:Disposable JugStorage:Store in sealed container at 59º to 86°F (15ºC to 30°C).  When reconstituted, keep solutionrefrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children.PEG-3350 and electrolytes for oral solution  NDC 40032-090-19In powdered form, for oral administration as a solution following reconstitution. PEG-3350 and electrolytes for oral solution, USP is available in a disposable jug in powdered form containing:Disposable JugStorage:Store in sealed container at 59º to 86°F (15ºC to 30°C).  When reconstituted, keep solutionrefrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children.PEG-3350 and electrolytes for oral solution  NDC 40032-090-19In powdered form, for oral administration as a solution following reconstitution. PEG-3350 and electrolytes for oral solution, USP is available in a disposable jug in powdered form containing:Disposable JugStorage:Store in sealed container at 59º to 86°F (15ºC to 30°C).  When reconstituted, keep solutionrefrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children.PEG-3350 and electrolytes for oral solution  NDC 40032-090-19In powdered form, for oral administration as a solution following reconstitution. PEG-3350 and electrolytes for oral solution, USP is available in a disposable jug in powdered form containing:Disposable JugStorage:Store in sealed container at 59º to 86°F (15ºC to 30°C).  When reconstituted, keep solutionrefrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children.PEG-3350 and electrolytes for oral solution  NDC 40032-090-19


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

The primary mode of action is thought to be through the osmotic effect of polyethylene glycol 3350 which causes water to be retained in the colon and produces a watery stool.

Non-Clinical Toxicology
Gastrointestinal (GI) obstruction, ileus, or gastric retention (, )

Bowel perforation (, )

Toxic colitis or toxic megacolon ()

Known allergy or hypersensitivity to components of PEG-3350 and electrolytes for oral solution (, )

Advise patients to hydrate adequately before, during, and after the use of PEG-3350 and electrolytes for oral solution.   Use caution in patients with congestive heart failure when replacing fluids. If a patient develops significant vomiting or signs of dehydration including signs of orthostatic hypotension after taking PEG-3350 and electrolytes for oral solution, consider performing post-colonoscopy lab tests (electrolytes, creatinine, and BUN) and treat accordingly. Fluid and electrolyte disturbances can lead to serious adverse events including cardiac arrhythmias, seizures and renal impairment. Fluid and electrolyte abnormalities should be corrected before treatment with PEG-3350 and electrolytes for oral solution.

In addition, use caution when prescribing PEG-3350 and electrolytes for oral solution for patients who have conditions, or who are using medications, that increase the risk for fluid and electrolyte disturbances or may increase the risk of adverse events of seizure, arrhythmias, and renal impairment []

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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