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AQUASOL A
Overview
What is AQUASOL A?
AQUASOL
Parenteral
Ordinarily oil-soluble, the vitamin A in this product has been water solubilized by special processing* and is available in a water solution for intramuscular injection.
One USP Unit is equivalent to one international unit (IU) and to 0.3 mcg of retinol or 0.6 mcg of betacarotene.
What does AQUASOL A look like?
What are the available doses of AQUASOL A?
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What should I talk to my health care provider before I take AQUASOL A?
Sorry No records found
How should I use AQUASOL A?
Vitamin A injection is effective for the treatment of vitamin A deficiency.
The parenteral administration is indicated when the oral administration is not feasible as in anorexia, nausea, vomiting, pre- and postoperative conditions, or it is not available as in the "Malabsorption Syndrome" with accompanying steatorrhea.
Pediatric Use:
Vitamin A supplementation for deficiency states in this population has been addressed by the Committee on Clinical Practice Issues of the American Society for Clinical Nutrition, by the American Society for Parenteral and Enteral Nutrition, and by the World Health Organization.
For intramuscular use.
Follow-up therapy with an oral therapeutic multivitamin preparation, containing 10,000 to 20,000 Units vitamin A for adults and for pediatric patients over 8 years old, and 5,000 to 10,000 Units for infants and other pediatric patients under 8 years old, is recommended daily for two months. Low birth-weight infants may require additional vitamin A though the exact dosing in these pediatric patients has not been established. In malabsorption, the parenteral route must be used for an equivalent preparation.
Poor dietary habits should be corrected and an abundant and well-balanced dietary intake should be prescribed.
What interacts with AQUASOL A?
The intravenous administration. Hypervitaminosis A. Sensitivity to any of the ingredients in this preparation.
Use in Pregnancy:
What are the warnings of AQUASOL A?
Patients receiving mitomycin should be observed for evidence of renal toxicity. Mitomycin should not be given to patients with a serum creatinine greater than 1.7 mg percent.
Avoid overdosage. Keep out of the reach of children.
Pediatric Use:
What are the precautions of AQUASOL A?
General:
Drug Interactions:
Carcinogenesis:
Pregnancy:
See section.
Nursing Mothers:
What are the side effects of AQUASOL A?
See section. Anaphylactic shock and death have been reported using the intravenous route. Allergic reactions have been reported rarely with administration of A including one case of an anaphylactoid type reaction.
What should I look out for while using AQUASOL A?
The intravenous administration. Hypervitaminosis A. Sensitivity to any of the ingredients in this preparation.
Use in Pregnancy:
Avoid overdosage. Keep out of the reach of children.
Pediatric Use:
What might happen if I take too much AQUASOL A?
The following amounts have been found to be toxic orally. Toxicity manifestations depend on the age, dosage, size, and duration of administration.
Acute toxicity
Chronic toxicity
Hypervitaminosis A Syndrome:
The treatment of hypervitaminosis A consists of immediate withdrawal of the vitamin along with symptomatic and supportive treatment.
How should I store and handle AQUASOL A?
AQUASOL Parenteral Store at 2–8°C (36–46°F). Do not freeze.Hospira, Inc., Lake Forest, IL 60045 USA LAB-1245-1.0Revised: 01/2018AQUASOL Parenteral Store at 2–8°C (36–46°F). Do not freeze.Hospira, Inc., Lake Forest, IL 60045 USA LAB-1245-1.0Revised: 01/2018AQUASOL Parenteral Store at 2–8°C (36–46°F). Do not freeze.Hospira, Inc., Lake Forest, IL 60045 USA LAB-1245-1.0Revised: 01/2018AQUASOL Parenteral Store at 2–8°C (36–46°F). Do not freeze.Hospira, Inc., Lake Forest, IL 60045 USA LAB-1245-1.0Revised: 01/2018AQUASOL Parenteral Store at 2–8°C (36–46°F). Do not freeze.Hospira, Inc., Lake Forest, IL 60045 USA LAB-1245-1.0Revised: 01/2018AQUASOL Parenteral Store at 2–8°C (36–46°F). Do not freeze.Hospira, Inc., Lake Forest, IL 60045 USA LAB-1245-1.0Revised: 01/2018
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
Beta-carotene, retinol, and retinal have effective and reliable vitamin A activity. Retinal and retinol are in chemical equilibrium in the body and have equivalent antixerophthalmic activity. Retinal combines with the rod pigment, opsin, in the retina to form rhodopsin, necessary for visual dark adaptation. Vitamin A prevents retardation of growth and preserves the epithelial cells' integrity. Normal adult liver storage is sufficient to satisfy two years' requirements of vitamin A.
Vitamin A is readily absorbed from the gastrointestinal tract, where the biosynthesis of vitamin A from beta-carotene takes place. Vitamin A absorption requires bile salts, pancreatic lipase, and dietary fat. It is transported in the blood to the liver by the chylomicron fraction of the lymph. Vitamin A is stored in Kupffer cells of the liver mainly as the palmitate. Normal serum vitamin A is 80–300 Units per 100 mL (plasma range is 30–70 mcg per dl) and for carotenoids 270–753 Units per 100 mL. The normal adult liver contains approximately 100 to 300 micrograms per gram, mostly as retinol palmitate.
*Oil-soluble vitamin A water solubilized with polysorbate 80.
Non-Clinical Toxicology
The intravenous administration. Hypervitaminosis A. Sensitivity to any of the ingredients in this preparation.Use in Pregnancy:
Avoid overdosage. Keep out of the reach of children.
Pediatric Use:
As with all drugs, the potential for interaction by a variety of mechanisms is a possibility.
General:
Drug Interactions:
Carcinogenesis:
Pregnancy:
See section.
Nursing Mothers:
See section. Anaphylactic shock and death have been reported using the intravenous route. Allergic reactions have been reported rarely with administration of A including one case of an anaphylactoid type reaction.
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
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