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CITRIC ACID MONOHYDRATE, TRISODIUM CITRATE DIHYDRATE, SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE, ANHYDROUS DEXTROSE

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Overview

What is Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?



What does Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D) look like?



What are the available doses of Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

The container for all CP2D and AS-3 solutions is a flexible polyvinyl chloride (PVC) bag sized for holding the appropriate amount of solution. The bag has a single port that is used for bag filling. The port is sealed after filling with a male luer assembly (CP2D) or female luer assembly (AS-3). Both the male and female luers are gamma irradiated prior to use. The plastic bag is contained in an overwrap which is added prior to sterilization.

The formulations for these products are as follows:

Citrate Phosphate Double Dextrose Solution (CP2D)

Additive Solution 3 (AS-3)

What should I talk to my health care provider before I take Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

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How should I use Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

The Haemonetics 250mL Anticoagulant Citrate Phosphate Double Dextrose (CP2D) and 250mL Additive Solution Formula 3 (AS-3) nutrient solution are intended to be used only with automated apheresis devices for collecting human blood and blood components. The anticoagulant solution is metered by the apheresis machine into the collected whole blood. It is not to be infused directly into the donor. After the anticoagulant is used, the bag in which it was contained is discarded. When collecting plasma in the RBCP protocol, the plasma is collected into an empty plasma collection bag. One hundred milliliters (100ml) of AS-3 is transferred into one RBC collection bag when using the RBCP protocol or 2 separate bags when using the 2RBC protocol. AS-3 solution provides nutrients to keep the red blood cells viable for 42 days when refrigerated.

CP2D is also indicated for the collection of FFP and PF24 plasma, collected and stored plasma collected using the 822, 822-2P and 822F-2P disposable sets may be frozen within 8 hours (FFP) or within 24 hours which includes 8 hours room temperature storage and 16 hours refrigeration storage (PF24).

The 300mL AS-3 is used in conjunction with automated red blood cell washing devices. AS-3 serves as the nutrient solution for storage of the red blood cell product after deglycerolization. The red blood cells are washed using the Model 215 System. AS-3 is used for priming the disposable and for the last wash of the red blood cells. The washed cells are then re-suspended in 100mL of the AS-3 before transfer into a product collection bag or storage bag. Additive Solution Formula 3 (AS-3) provides nutrients to keep the washed red blood cells viable for up to 14 days after washing when refrigerated.

Neither the CP2D nor the AS-3 container is used for the storage of blood or blood components.

CP2D Anticoagulant Solution and AS-3 Solution may be used with Haemonetics apheresis devices. See the Haemonetics Operation Manual for full operating instructions.

Prior to use of the solutions, check the solutions for leaks by squeezing each of the bags firmly. If leaks are found, discard the solution.


What interacts with Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

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What are the warnings of Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

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What are the precautions of Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

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What are the side effects of Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

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What should I look out for while using Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?


What might happen if I take too much Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

Both solutions are intended to be used only with automated apheresis devices for collecting human blood and blood components. CP2D is used as an anticoagulant solution and AS-3 is intended for use a nutrient solution. Neither solution is intended for direct infusion.


How should I store and handle Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D)?

Unopened vials of gemcitabine for injection, USP are stable until the expiration date indicated on the package when stored at controlled room temperature 20° to 25°C (68° to 77°F) and that allows for excursions between 15° and 30°C (59° and 86°F) [see USP Controlled Room Temperature] [ ] 250mL CP2D Anticoagulant Solution is supplied in flexible PVC containers with a sterile, non-pyrogenic fluid path. 250mL and 300mL AS-3 Nutrient Solution is supplied in flexible PVC containers with a sterile, non-pyrogenic fluid path.