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PLASMA-LYTE 56
Overview
What is PLASMA-LYTE 56?
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) is a sterile,
nonpyrogenic, hypotonic solution in a single dose container for
intravenous administration. Each 100 mL contains 234 mg of Sodium
Chloride, USP (NaCl); 128 mg of Potassium Acetate, USP
(CHKO); and 32 mg of Magnesium
Acetate Tetrahydrate
(Mg(CHO)•4HO).
It contains no antimicrobial agents. The pH is adjusted with
hydrochloric acid. The pH is 5.5 (4.0 to 8.0).
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) administered
intravenously has value as a source of water and electrolytes. One liter
has an ionic concentration of 40 mEq sodium, 13 mEq potassium, 3 mEq
magnesium, 40 mEq chloride, and 16 mEq acetate. The osmolarity is 111
mOsmol/L (calc). Normal physiologic osmolarity range is approximately
280 to 310 mOsmol/L. Administration of substantially hypertonic
solutions may cause vein damage.
The VIAFLEX plastic container is fabricated from a specially formulated polyvinyl chloride
(PL 146 Plastic). The amount of water that can permeate from inside the
container into the overwrap is insufficient to affect the solution
significantly. Solutions in contact with the plastic container can leach
out certain of its chemical components in very small amounts within the
expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts
per million. However, the safety of the plastic has been confirmed in
tests in animals according to USP biological tests for plastic
containers as well as by tissue culture toxicity studies.
What does PLASMA-LYTE 56 look like?
What are the available doses of PLASMA-LYTE 56?
Sorry No records found.
What should I talk to my health care provider before I take PLASMA-LYTE 56?
Sorry No records found
How should I use PLASMA-LYTE 56?
Sorry No records found
What interacts with PLASMA-LYTE 56?
None known
What are the warnings of PLASMA-LYTE 56?
Prolonged use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections due to fungi or viruses.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with great care, if at all, in patients with congestive heart failure,
severe renal insufficiency and in clinical states in which there exists
edema with sodium retention.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with great care, if at all, in patients with hyperkalemia, severe renal
failure and in conditions in which potassium retention is present.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with great care in patients with metabolic or respiratory alkalosis. The
administration of acetate ions should be done with great care in those
conditions in which there is an increased level or an impaired
utilization of these ions, such as severe hepatic insufficiency.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should not be
administered simultaneously with blood through the same administration
set because of the possibility of hemolysis.
The intravenous
administration of PLASMA-LYTE 56 Injection (Multiple Electrolytes
Injection, Type 1, USP) can cause fluid and/or solute overloading
resulting in dilution of serum electrolyte concentrations,
overhydration, congested states or pulmonary edema. The risk of
dilutional states is inversely proportional to the electrolyte
concentrations of the injection. The risk of solute overload causing
congested states with peripheral and pulmonary edema is directly
proportional to the electrolyte concentrations of the injection.
In patients with
diminished renal function, administration of PLASMA-LYTE 56 Injection
(Multiple Electrolytes Injection, Type 1, USP) may result in sodium or
potassium retention.
What are the precautions of PLASMA-LYTE 56?
Clinical evaluation
and periodic laboratory determinations are necessary to monitor changes
in fluid balance, electrolyte concentrations and acid base balance
during prolonged parenteral therapy or whenever the condition of the
patient warrants such evaluation.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with caution. Excess administration may result in metabolic alkalosis.
Caution must be
exercised in the administration of PLASMA-LYTE 56 Injection (Multiple
Electrolytes Injection, Type 1, USP) to patients receiving
corticosteroids or corticotropin.
Pregnancy
Pediatric Use
Safety and
effectiveness of PLASMA-LYTE 56 Injection (Multiple Electrolytes
Injection, Type 1, USP) in pediatric patients have not been
established by adequate and well controlled trials, however, the
use of electrolyte solutions in the pediatric population is
referenced in the medical literature. The warnings, precautions
and adverse reactions identified in the label copy should be
observed in the pediatric population.
Geriatric Use
Clinical
studies of PLASMA-LYTE 56 Injection (Multiple Electrolytes
Injection, Type 1, USP) did not include sufficient numbers of
subjects aged 65 and over to determine whether they respond
differently from younger subjects. Other reported clinical
experience has not identified differences in responses between
the elderly and younger patients. In general, dose selection for
an elderly patient should be cautious, usually starting at the
low end of the dosing range, reflecting the greater frequency of
decreased hepatic, renal, or cardiac function, and of
concomitant disease or drug therapy.
Do not
administer unless solution is clear and seal is
intact.
What are the side effects of PLASMA-LYTE 56?
Reactions which may
occur because of the solution or the technique of administration include
febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and
hypervolemia.
If an adverse
reaction does occur, discontinue the infusion, evaluate the patient,
institute appropriate therapeutic countermeasures and save the remainder
of the fluid for examination if deemed necessary.
What should I look out for while using PLASMA-LYTE 56?
None
known
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with great care, if at all, in patients with congestive heart failure,
severe renal insufficiency and in clinical states in which there exists
edema with sodium retention.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with great care, if at all, in patients with hyperkalemia, severe renal
failure and in conditions in which potassium retention is present.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should be used
with great care in patients with metabolic or respiratory alkalosis. The
administration of acetate ions should be done with great care in those
conditions in which there is an increased level or an impaired
utilization of these ions, such as severe hepatic insufficiency.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) should not be
administered simultaneously with blood through the same administration
set because of the possibility of hemolysis.
The intravenous
administration of PLASMA-LYTE 56 Injection (Multiple Electrolytes
Injection, Type 1, USP) can cause fluid and/or solute overloading
resulting in dilution of serum electrolyte concentrations,
overhydration, congested states or pulmonary edema. The risk of
dilutional states is inversely proportional to the electrolyte
concentrations of the injection. The risk of solute overload causing
congested states with peripheral and pulmonary edema is directly
proportional to the electrolyte concentrations of the injection.
In patients with
diminished renal function, administration of PLASMA-LYTE 56 Injection
(Multiple Electrolytes Injection, Type 1, USP) may result in sodium or
potassium retention.
What might happen if I take too much PLASMA-LYTE 56?
Sorry No Records found
How should I store and handle PLASMA-LYTE 56?
PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) in VIAFLEX plastic containers is available as shown below:Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) in VIAFLEX plastic containers is available as shown below:Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) has value as a
source of water and electrolytes. It is capable of inducing diuresis
depending on the clinical condition of the patient.
PLASMA-LYTE 56
Injection (Multiple Electrolytes Injection, Type 1, USP) produces a
metabolic alkalinizing effect. Acetate ions are metabolized ultimately
to carbon dioxide and water, which requires the consumption of hydrogen
cations.
Non-Clinical Toxicology
None knownPLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention.
PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with great care, if at all, in patients with hyperkalemia, severe renal failure and in conditions in which potassium retention is present.
PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with great care in patients with metabolic or respiratory alkalosis. The administration of acetate ions should be done with great care in those conditions in which there is an increased level or an impaired utilization of these ions, such as severe hepatic insufficiency.
PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should not be administered simultaneously with blood through the same administration set because of the possibility of hemolysis.
The intravenous administration of PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injection. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of the injection.
In patients with diminished renal function, administration of PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) may result in sodium or potassium retention.
Antidiabetic drug requirements, i.e., insulin, may be altered in association with the use of Diethylpropion hydrochloride and the concomitant dietary regimen. Concurrent use with general anesthetics may result in arrhythmias. The presser effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs, i.e., guanethidine, a-methyldopa. Concurrent use of phenothiazines may antagonize the anorectic effect of diethylpropion.
Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations and acid base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation.
PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) should be used with caution. Excess administration may result in metabolic alkalosis.
Caution must be exercised in the administration of PLASMA-LYTE 56 Injection (Multiple Electrolytes Injection, Type 1, USP) to patients receiving corticosteroids or corticotropin.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
Review
Professional
Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72Tips
Tips
Interactions
Interactions
A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).