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Phendimetrazine Tartrate
Overview
What is Phendimetrazine Tartrate?
Phendimetrazine tartrate, as the dextro isomer, has the chemical
name of (2, 3)-3,
4-Dimethyl-2-phenylmorpholine L-(+)-tartrate (1:1).
Phendimetrazine tartrate is a white, odorless crystalline powder. It is
freely soluble in water; sparingly soluble in warm alcohol, insoluble in
chloroform, acetone, ether and benzene.
Each tablet, for oral administration, contains 35 mg of phendimetrazine
tartrate. In addition, each tablet contains the following inactive ingredients:
colloidal silicon dioxide, croscarmellose sodium, dibasic calcium phosphate
dihydrate, magnesium stearate, microcrystalline cellulose and FD and C Blue #1
Lake or FD and C Yellow #6 and D and C Yellow #10 as coloring
What does Phendimetrazine Tartrate look like?
What are the available doses of Phendimetrazine Tartrate?
Sorry No records found.
What should I talk to my health care provider before I take Phendimetrazine Tartrate?
Sorry No records found
How should I use Phendimetrazine Tartrate?
Usual Adult Dose: 1 tablet (35 mg) b.i.d. or t.i.d., one hour
before meals.
Dosage should be individualized to obtain an adequate response with the
lowest effective dosage. In some cases, 1/2 tablet (17.5 mg) per dose may be
adequate. Dosage should not exceed 2 tablets t.i.d.
What interacts with Phendimetrazine Tartrate?
Known hypersensitivity or idiosyncratic reactions to sympathomimetics.
Advanced arteriosclerosis, symptomatic cardiovascular disease, moderate and severe hypertension, hyperthyroidism, and glaucoma.
Highly nervous or agitated patients.
Patients with a history of drug abuse.
Patients taking other CNS stimulants, including monoamine oxidase inhibitors
What are the warnings of Phendimetrazine Tartrate?
Sorry No Records found
What are the precautions of Phendimetrazine Tartrate?
Sorry No Records found
What are the side effects of Phendimetrazine Tartrate?
Cardiovascular:
Central Nervous System:
Gastrointestinal:
Genitourinary:
What should I look out for while using Phendimetrazine Tartrate?
Tolerance to the anorectic effect of phendimetrazine develops
within a few weeks. When this occurs, its use should be discontinued; the
maximum recommended dose should not be exceeded.
Use of phendimetrazine tartrate within 14 days following the administration
of monoamine oxidase inhibitors may result in a hypertensive crisis.
Abrupt cessation of administration following prolonged high dosage results in
extreme fatigue and depression. Because of the effect on the central nervous
system, phendimetrazine may impair the ability of the patient to engage in
potentially hazardous activities such as operating machinery or driving a motor
vehicle; the patient should therefore be cautioned accordingly.
What might happen if I take too much Phendimetrazine Tartrate?
Acute overdosage with phendimetrazine tartrate may manifest
itself by the following signs and symptoms: unusual restlessness, confusion,
belligerence, hallucinations, and panic states. Fatigue and depression usually
follow the central stimulation. Cardiovascular effects include arrhythmias,
hypertension, or hypotension and circulatory collapse. Gastrointestinal symptoms
include nausea, vomiting, diarrhea, and abdominal cramps. Poisoning may result
in convulsions, coma, and death.
The management of overdosage is largely symptomatic. It includes sedation
with a barbiturate. If hypertension is marked, the use of a nitrate or
rapid-acting alpha receptor-blocking agent should be considered. Experience with
hemodialysis or peritoneal dialysis is inadequate to permit recommendations for
its use.
How should I store and handle Phendimetrazine Tartrate?
Each single-scored, yellow, round tablet contains 35 mg phendimetrazine tartrate. Tablets are supplied as follows:Store at controlled room temperature 15º-30ºC (59º-86ºF).Dispense in tight containers with child-resistant closures.Distributed By: Bryant Ranch Prepack12623 Sherman Way North Hollywood, CA 91605 Voice (877) 885-0882 Fax (877) 277-7552Each single-scored, yellow, round tablet contains 35 mg phendimetrazine tartrate. Tablets are supplied as follows:Store at controlled room temperature 15º-30ºC (59º-86ºF).Dispense in tight containers with child-resistant closures.Distributed By: Bryant Ranch Prepack12623 Sherman Way North Hollywood, CA 91605 Voice (877) 885-0882 Fax (877) 277-7552Each single-scored, yellow, round tablet contains 35 mg phendimetrazine tartrate. Tablets are supplied as follows:Store at controlled room temperature 15º-30ºC (59º-86ºF).Dispense in tight containers with child-resistant closures.Distributed By: Bryant Ranch Prepack12623 Sherman Way North Hollywood, CA 91605 Voice (877) 885-0882 Fax (877) 277-7552Each single-scored, yellow, round tablet contains 35 mg phendimetrazine tartrate. Tablets are supplied as follows:Store at controlled room temperature 15º-30ºC (59º-86ºF).Dispense in tight containers with child-resistant closures.Distributed By: Bryant Ranch Prepack12623 Sherman Way North Hollywood, CA 91605 Voice (877) 885-0882 Fax (877) 277-7552
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
Phendimetrazine tartrate tablets are indicated in the management of exogenous
obesity as a short term adjunct (a few weeks) in a regimen of weight reduction
based on caloric restriction. The limited usefulness of agents of this class
(see CLINICAL PHARMACOLOGY) should be measured against
possible risk factors inherent in their use such as those described below.
Non-Clinical Toxicology
Tolerance to the anorectic effect of phendimetrazine develops within a few weeks. When this occurs, its use should be discontinued; the maximum recommended dose should not be exceeded.Use of phendimetrazine tartrate within 14 days following the administration of monoamine oxidase inhibitors may result in a hypertensive crisis.
Abrupt cessation of administration following prolonged high dosage results in extreme fatigue and depression. Because of the effect on the central nervous system, phendimetrazine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly.
Caution is to be exercised in prescribing phendimetrazine tartrate for patients with even mild hypertension.
Insulin requirements in diabetes mellitus may be altered in association with the use of phendimetrazine and the concomitant dietary regimen.
Phendimetrazine may decrease the hypotensive effect of guanethidine.
The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage.
Safe use in pregnancy has not been established. Until more information is available, phendimetrazine tartrate should not be taken by women who are or may become pregnant unless, in the opinion of the physician, the potential benefits outweigh the possible hazards.
Phendimetrazine tartrate is not recommended for use in pediatric patients under 12 years of age.
Cardiovascular:
Central Nervous System:
Gastrointestinal:
Genitourinary:
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
Review
Professional
Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72Tips
Tips
Interactions
Interactions
A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).