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Sodium Sulfacetamide

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Overview

What is Sodium Sulfacetamide?

Sodium Sulfacetamide Medicated Pads 10%

Sodium Sulfacetamide Medicated Pads

Sodium sulfacetamide is a sulfonamide with antibacterial activity. Chemically, sodium sulfacetamide is CHNNa0S•HO, with a molecular weight of 254.24. Chemically it is acetamide, N- [(4 aminophenyl) sulfonyl]-, monosodium salt and monohydrate, with the following structural formula:



What does Sodium Sulfacetamide look like?



What are the available doses of Sodium Sulfacetamide?

Sorry No records found.

What should I talk to my health care provider before I take Sodium Sulfacetamide?

Sorry No records found

How should I use Sodium Sulfacetamide?

Sodium Sulfacetamide Medicated Pads

Gently apply to the affected areas 1 to 2 times daily or as directed by a physician until the infection has cleared.


What interacts with Sodium Sulfacetamide?

Sorry No Records found


What are the warnings of Sodium Sulfacetamide?

Sorry No Records found


What are the precautions of Sodium Sulfacetamide?

Sorry No Records found


What are the side effects of Sodium Sulfacetamide?

Sorry No records found


What should I look out for while using Sodium Sulfacetamide?

Sodium Sulfacetamide Medicated Pads

Sodium Sulfacetamide Medicated Pads

Although rare, sensitivity t o sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, and contact dermatitis indicate hypersensitivity to sulfonamides. Sulfonamides are known to cause Stevens-Johnson syndrome in hypersensitive individuals. Stevens-Johnson syndrome also has been reported following the use of sodium sulfacetamide topically. Cases of drug-induced systemic lupus erythematosus from topical sulfacetamide also have been reported.


What might happen if I take too much Sodium Sulfacetamide?

Sorry No Records found


How should I store and handle Sodium Sulfacetamide?

Store at room temperature 15º-30ºC (59º-86ºF).Keep tightly closed.Store at room temperature 15º-30ºC (59º-86ºF).Keep tightly closed.Sodium Sulfacetamide Medicated PadsStore at 15°-30° C (59°-86° F). Protect from freezing.Sodium Sulfacetamide Medicated PadsManufactured for: E. FOUGERA & CO.A division of Nycomed US Inc., Melville New York 11747Manufactured by: Pegasus Laboratories, Inc., Pensacola, FL 32514 IL302A R3/09 Sodium Sulfacetamide Medicated PadsStore at 15°-30° C (59°-86° F). Protect from freezing.Sodium Sulfacetamide Medicated PadsManufactured for: E. FOUGERA & CO.A division of Nycomed US Inc., Melville New York 11747Manufactured by: Pegasus Laboratories, Inc., Pensacola, FL 32514 IL302A R3/09 Sodium Sulfacetamide Medicated PadsStore at 15°-30° C (59°-86° F). Protect from freezing.Sodium Sulfacetamide Medicated PadsManufactured for: E. FOUGERA & CO.A division of Nycomed US Inc., Melville New York 11747Manufactured by: Pegasus Laboratories, Inc., Pensacola, FL 32514 IL302A R3/09 Sodium Sulfacetamide Medicated PadsStore at 15°-30° C (59°-86° F). Protect from freezing.Sodium Sulfacetamide Medicated PadsManufactured for: E. FOUGERA & CO.A division of Nycomed US Inc., Melville New York 11747Manufactured by: Pegasus Laboratories, Inc., Pensacola, FL 32514 IL302A R3/09 Sodium Sulfacetamide Medicated PadsStore at 15°-30° C (59°-86° F). Protect from freezing.Sodium Sulfacetamide Medicated PadsManufactured for: E. FOUGERA & CO.A division of Nycomed US Inc., Melville New York 11747Manufactured by: Pegasus Laboratories, Inc., Pensacola, FL 32514 IL302A R3/09


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Sodium sulfacetamide exerts a bacteriostatic effect against sulfonamide-sensitive gram-positive and gram-negative micro-organism including commonly isolasted from secondary cutaneous pyogenic infections.

The most widely accepted mechanism of action of sulfonamides is the Woods-Fildes theory, which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid P ( ABA), an essential component for bacterial growth. While absorption through intact skin in humans has not been determined, sodium sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine largely unchanged. The biological half-life has variously been reported as 7 o t 12.8 hours.

Non-Clinical Toxicology
Sodium Sulfacetamide Medicated Pads

Sodium Sulfacetamide Medicated Pads

Although rare, sensitivity t o sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, and contact dermatitis indicate hypersensitivity to sulfonamides. Sulfonamides are known to cause Stevens-Johnson syndrome in hypersensitive individuals. Stevens-Johnson syndrome also has been reported following the use of sodium sulfacetamide topically. Cases of drug-induced systemic lupus erythematosus from topical sulfacetamide also have been reported.

Drug Interactions.

I. Due to the competition of salicylate with other drugs for binding to serum albumin the following drug interactions may occur:

II. Drugs changing salicylate levels by altering renal tubular reabsorption:

III. Drugs with complicated interactions with salicylates:

The following alterations of laboratory tests have been reported during salicylate therapy:

General:

Sodium Sulfacetamide Medicated Pads

Reports of irritation and hypersensitivity to sodium sulfacetamide are uncommon. The following adverse reactions, reported after administration of sterile ophthalmic sodium sulfacetamide, are noteworthy: instances of Stevens-Johnson syndrome and instances of local hypersensitivity, which progressed to a syndrome resembling systemic lupus erythematosus; in one case a fatal outcome has been reported (see ).

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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