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Tinidazole

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Overview

What is Tinidazole?

Tinidazole is a synthetic antiprotozoal and antibacterial agent. It is 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole, a second-generation 2-methyl-5-nitroimidazole, which has the following chemical structure:

Tinidazole Tablets pink oral tablets contain 250 mg or 500 mg of tinidazole. Inactive ingredients include pregelatinized starch NF, croscarmellose sodium NF, magnesium stearate NF, microcrystalline cellulose NF, polyvinyl alcohol-part hydrolyzed USP, titanium dioxide USP, polyethylene glycol 3000 NF, talc USP, and FD&C red # 40 aluminum lake.



What does Tinidazole look like?



What are the available doses of Tinidazole?

Tablets: 250 mg and 500 mg ()

What should I talk to my health care provider before I take Tinidazole?

How should I use Tinidazole?

Tinidazole is indicated for the treatment of trichomoniasis caused by The organism should be identified by appropriate diagnostic procedures. Because trichomoniasis is a sexually transmitted disease with potentially serious sequelae, partners of infected patients should be treated simultaneously in order to prevent re-infection

It is advisable to take tinidazole with food to minimize the incidence of epigastric discomfort and other gastrointestinal side-effects. Food does not affect the oral bioavailability of tinidazole [].

Alcoholic beverages should be avoided when taking tinidazole and for 3 days afterwards [].


What interacts with Tinidazole?

Sorry No Records found


What are the warnings of Tinidazole?

Sorry No Records found


What are the precautions of Tinidazole?

Sorry No Records found


What are the side effects of Tinidazole?

Sorry No records found


What should I look out for while using Tinidazole?

Prior history of hypersensitivity to tinidazole or other nitroimidazole derivatives (, ,)

First trimester of pregnancy (,)

Nursing mothers, unless breast-feeding is interrupted during tinidazole therapy and for 3 days following the last dose (, )

WARNING: POTENTIAL RISK FOR CARCINOGENICITY

Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent (). Although such data have not been reported for tinidazole, the two drugs are structurally related and have similar biologic effects.


What might happen if I take too much Tinidazole?

There are no reported overdoses with tinidazole in humans.

Treatment of Overdosage


How should I store and handle Tinidazole?

Store at 25°C (77°F): excursions permitted to 15–30°C (59–86°F) [see USP Controlled Room Temperature]. Keep out of reach of children. Store at 25°C (77°F): excursions permitted to 15–30°C (59–86°F) [see USP Controlled Room Temperature]. Keep out of reach of children. Tinidazole Tablets 250 mg tablets are pink, round, scored tablets, debossed with "N" scored "L" on one side and "550" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-550-04    Bottle of 40Tinidazole Tablets 500 mg tablets are pink, oval, scored tablets, debossed with "N" scored "L" on one side and "551" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-551-06    Bottle of 60NDC 43386-551-02    Bottle of 20Storage:Tinidazole Tablets 250 mg tablets are pink, round, scored tablets, debossed with "N" scored "L" on one side and "550" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-550-04    Bottle of 40Tinidazole Tablets 500 mg tablets are pink, oval, scored tablets, debossed with "N" scored "L" on one side and "551" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-551-06    Bottle of 60NDC 43386-551-02    Bottle of 20Storage:Tinidazole Tablets 250 mg tablets are pink, round, scored tablets, debossed with "N" scored "L" on one side and "550" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-550-04    Bottle of 40Tinidazole Tablets 500 mg tablets are pink, oval, scored tablets, debossed with "N" scored "L" on one side and "551" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-551-06    Bottle of 60NDC 43386-551-02    Bottle of 20Storage:Tinidazole Tablets 250 mg tablets are pink, round, scored tablets, debossed with "N" scored "L" on one side and "550" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-550-04    Bottle of 40Tinidazole Tablets 500 mg tablets are pink, oval, scored tablets, debossed with "N" scored "L" on one side and "551" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-551-06    Bottle of 60NDC 43386-551-02    Bottle of 20Storage:Tinidazole Tablets 250 mg tablets are pink, round, scored tablets, debossed with "N" scored "L" on one side and "550" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-550-04    Bottle of 40Tinidazole Tablets 500 mg tablets are pink, oval, scored tablets, debossed with "N" scored "L" on one side and "551" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-551-06    Bottle of 60NDC 43386-551-02    Bottle of 20Storage:Tinidazole Tablets 250 mg tablets are pink, round, scored tablets, debossed with "N" scored "L" on one side and "550" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-550-04    Bottle of 40Tinidazole Tablets 500 mg tablets are pink, oval, scored tablets, debossed with "N" scored "L" on one side and "551" on the other side, supplied in bottles with child-resistant caps as:NDC 43386-551-06    Bottle of 60NDC 43386-551-02    Bottle of 20Storage:


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Tinidazole is an antiprotozoal, antibacterial agent. [].

Non-Clinical Toxicology
Prior history of hypersensitivity to tinidazole or other nitroimidazole derivatives (, ,)

First trimester of pregnancy (,)

Nursing mothers, unless breast-feeding is interrupted during tinidazole therapy and for 3 days following the last dose (, )

WARNING: POTENTIAL RISK FOR CARCINOGENICITY

Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent (). Although such data have not been reported for tinidazole, the two drugs are structurally related and have similar biologic effects.

See .

Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, have been reported in patients treated with tinidazole. The appearance of abnormal neurologic signs demands the prompt discontinuation of tinidazole therapy.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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