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Ximino
Overview
What is Ximino?
The active ingredient in Ximino Extended-Release Capsules is minocycline hydrochloride, a semi synthetic derivative of tetracycline. Ximino is a tetracycline-class drug. Ximino is known chemically as [4(4α,4aα,5aα,12aα)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide mono hydrochloride.
The structural formula is represented below:
Minocycline hydrochloride, USP is a yellow crystalline powder, sparingly soluble in water, soluble in solutions of alkali hydroxides and carbonates, slightly soluble in alcohol, practically insoluble in chloroform and in ether.
Ximino (minocycline hydrochloride) Extended-Release Capsules for oral administration contain minocycline hydrochloride, USP equivalent to 45 mg, 90 mg, or 135 mg of minocycline. The Extended-Release Capsules contain the following inactive ingredients: colloidal silicon dioxide, D&C Yellow #10 (in 45 mg strength), FD&C Blue #1, FD&C Yellow #6 (in 45 mg and 135 mg strength), gelatin, hypromellose, lactose monohydrate, magnesium stearate, sodium lauryl sulfate, and titanium dioxide.
The 45 mg, 90 mg, and 135 mg capsules also contain Opadry Clear which contains hypromellose, polyethylene glycol 400, polyethylene glycol 6000, and talc.
Ximino Extended-Release Capsules also contain black ink which contains black iron oxide, potassium hydroxide, propylene glycol, and shellac.
What does Ximino look like?
What are the available doses of Ximino?
Extended-Release Capsules: 45 mg, 90 mg, and 135 mg (3)
What should I talk to my health care provider before I take Ximino?
How should I use Ximino?
Ximino is indicated to treat only inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 12 years of age and older.
To reduce the development of drug-resistant bacteria as well as to maintain the effectiveness of other antibacterial drugs, Ximino should be used only as indicated .
The recommended dosage of Ximino is approximately 1 mg/kg once daily for 12 weeks. Higher doses have not shown to be of additional benefit in the treatment of inflammatory lesions of acne, and may be associated with more acute vestibular side effects.
The following table shows capsule strength and body weight to achieve approximately 1 mg/kg.
Ximino may be taken with or without food . The capsules should be swallowed whole without chewing, crushing or splitting. Ingestion of food along with Ximino may help reduce the risk of esophageal irritation and ulceration.
In patients with renal impairment, the total dosage should be decreased by either reducing the recommended individual doses and/or by extending the time intervals between doses .
What interacts with Ximino?
Sorry No Records found
What are the warnings of Ximino?
Sorry No Records found
What are the precautions of Ximino?
Sorry No Records found
What are the side effects of Ximino?
Sorry No records found
What should I look out for while using Ximino?
Ximino is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines .
What might happen if I take too much Ximino?
In case of overdosage, discontinue medication, treat symptomatically and institute supportive measures. Minocycline is not removed in significant quantities by hemodialysis or peritoneal dialysis.
How should I store and handle Ximino?
Shake well before using. Store at controlled room temperature 20° to 25°C (68° to 77°F). Dispense in a well-closed container as defined in the USP.Naproxen Tablets, USP:375 mgStore at 15°-30°C (59°-86°F) in well-closed containers; dispense in light-resistant containers.Rx onlyNaproxen Tablets, USP:375 mgStore at 15°-30°C (59°-86°F) in well-closed containers; dispense in light-resistant containers.Rx onlyNaproxen Tablets, USP:375 mgStore at 15°-30°C (59°-86°F) in well-closed containers; dispense in light-resistant containers.Rx onlyNaproxen Tablets, USP:375 mgStore at 15°-30°C (59°-86°F) in well-closed containers; dispense in light-resistant containers.Rx only
