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Ciprofloxacin Otic

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Overview

What is Ciprofloxacin Otic?

Ciprofloxacin Otic Solution 0.2% contains the synthetic antimicrobial agent ciprofloxacin hydrochloride. Ciprofloxacin Otic Solution is a sterile, preservative-free solution for otic use. Each single use container of Ciprofloxacin Otic Solution delivers 0.25 mL of solution equivalent to 0.5 mg of ciprofloxacin. The inactive ingredients are povidone, glycerin, and water for injection. Sodium hydroxide and/or lactic acid may be added to adjust pH.

Ciprofloxacin, a fluroquinolone is available as the monohydrochloride, monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its molecular formula is CHFNO•HCl•HO, and molecular weight is 385.82.

The chemical structure of ciprofloxacin hydrochloride is:



What does Ciprofloxacin Otic look like?



What are the available doses of Ciprofloxacin Otic?

Ciprofloxacin Otic Solution is a sterile, preservative-free otic solution of ciprofloxacin hydrochloride equivalent to 0.2 % ciprofloxacin (0.5 mg in 0.25 mL) in each single use container. ()

What should I talk to my health care provider before I take Ciprofloxacin Otic?

How should I use Ciprofloxacin Otic?

Ciprofloxacin Otic Solution is a quinolone antimicrobial indicated for the treatment of acute otitis externa due to susceptible isolates of or .

The contents of one single use container (deliverable volume: 0.25 mL) should be instilled into the affected ear twice daily (approximately 12 hours apart) for 7 days.

Wash hands before use. The solution should be warmed, by holding the container in the hands for at least 1 minute, to minimize the dizziness that may result from the instillation of a cold solution into the ear canal. The patient should lie with the affected ear upward and then the solution should be instilled. This position should be maintained for at least 1 minute to facilitate penetration of the drops into the ear. Repeat, if necessary, for the opposite ear.


What interacts with Ciprofloxacin Otic?

Sorry No Records found


What are the warnings of Ciprofloxacin Otic?

Sorry No Records found


What are the precautions of Ciprofloxacin Otic?

Sorry No Records found


What are the side effects of Ciprofloxacin Otic?

Sorry No records found


What should I look out for while using Ciprofloxacin Otic?

Ciprofloxacin Otic Solution is contraindicated in persons with a history of hypersensitivity to ciprofloxacin.


What might happen if I take too much Ciprofloxacin Otic?

Sorry No Records found


How should I store and handle Ciprofloxacin Otic?

Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayStore at 20-25°C (68-77°F) [see USP Controlled Room Temperature].ArrayManufactured by:Hi-Tech Pharmacal Co., Inc.Amityville, NY 11701Made in U.S.A.ArrayCiprofloxacin Otic Solution is a clear, colorless, sterile, preservative-free solution. Ciprofloxacin Otic Solution is supplied as a 0.2% otic solution in a low-density polyethylene (LDPE) single use container. Each single use container delivers 0.25 mL of solution equivalent to 0.5 mg of ciprofloxacin; 14 single use containers are packaged in a foil overwrap pouch in a carton (NDC 42195-550-14).


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Ciprofloxacin is a fluoroquinolone antimicrobial (see ).

Non-Clinical Toxicology
Ciprofloxacin Otic Solution is contraindicated in persons with a history of hypersensitivity to ciprofloxacin.

Ciprofloxacin Otic Solution is for otic use only. It should not be used for injection, for inhalation or for topical ophthalmic use.

Because clinical studies are conducted under widely varying conditions, adverse drug reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice.

In a randomized, active-controlled clinical trial, approximately 300 patients with clinical signs and symptoms of otitis externa were treated with Ciprofloxacin Otic Solution. The most frequently reported adverse reactions were application site pain, ear pruritus, fungal ear superinfection, and headache, each reported in approximately 2-3% of patients.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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