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ALPHAGAN P

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Overview

What is ALPHAGAN P?

ALPHAGAN

P

The structural formula of brimonidine tartrate is:

5-Bromo-6-(2-imidazolidinylideneamino) quinoxaline L-tartrate; MW= 442.24

In solution, (brimonidine tartrate ophthalmic solution) has a clear, greenish-yellow color. It has an osmolality of 250-350 mOsmol/kg and a pH of 7.4-8.0 (0.1%) or 6.9-7.4 (0.15%).

Brimonidine tartrate appears as an off-white to pale-yellow powder and is soluble in both water (0.6 mg/mL) and in the product vehicle (1.4 mg/mL) at pH 7.7.

Each mL of contains the active ingredient brimonidine tartrate 0.1% (1 mg/mL) or 0.15% (1.5 mg/mL) with the inactive ingredients sodium carboxymethylcellulose; sodium borate; boric acid; sodium chloride; potassium chloride; calcium chloride; magnesium chloride; PURITE 0.005% (0.05 mg/mL) as a preservative; purified water; and hydrochloric acid and/or sodium hydroxide to adjust pH.



What does ALPHAGAN P look like?



What are the available doses of ALPHAGAN P?

Solution containing 1 or 1.5 mg/mL brimonidine tartrate. ()

What should I talk to my health care provider before I take ALPHAGAN P?

Use with caution in children ≥ 2 years of age. ()

How should I use ALPHAGAN P?

ALPHAGAN

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The recommended dose is one drop of in the affected eye(s) three times daily, approximately 8 hours apart. ophthalmic solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. If more than one topical ophthalmic product is to be used, the different products should be instilled at least 5 minutes apart.


What interacts with ALPHAGAN P?

Sorry No Records found


What are the warnings of ALPHAGAN P?

Sorry No Records found


What are the precautions of ALPHAGAN P?

Sorry No Records found


What are the side effects of ALPHAGAN P?

Sorry No records found


What should I look out for while using ALPHAGAN P?

Neonates and infants (under the age of 2 years). ()


What might happen if I take too much ALPHAGAN P?

Very limited information exists on accidental ingestion of brimonidine in adults; the only adverse reaction reported to date has been hypotension. Symptoms of brimonidine overdose have been reported in neonates, infants, and children receiving as part of medical treatment of congenital glaucoma or by accidental oral ingestion (see , ). Treatment of an oral overdose includes supportive and symptomatic therapy; a patent airway should be maintained.


How should I store and handle ALPHAGAN P?

ALPHAGANP0.1%5 mL in 10 mL bottle              NDC 0023-9321-0510 mL in 10 mL bottle            NDC 0023-9321-1015 mL in 15 mL bottle            NDC 0023-9321-15 0.15%5 mL in 10 mL bottle              NDC 0023-9177-0510 mL in 10 mL bottle            NDC 0023-9177-1015 mL in 15 mL bottle            NDC 0023-9177-15 ALPHAGANP0.1%5 mL in 10 mL bottle              NDC 0023-9321-0510 mL in 10 mL bottle            NDC 0023-9321-1015 mL in 15 mL bottle            NDC 0023-9321-15 0.15%5 mL in 10 mL bottle              NDC 0023-9177-0510 mL in 10 mL bottle            NDC 0023-9177-1015 mL in 15 mL bottle            NDC 0023-9177-15 ALPHAGANP0.1%5 mL in 10 mL bottle              NDC 0023-9321-0510 mL in 10 mL bottle            NDC 0023-9321-1015 mL in 15 mL bottle            NDC 0023-9321-15 0.15%5 mL in 10 mL bottle              NDC 0023-9177-0510 mL in 10 mL bottle            NDC 0023-9177-1015 mL in 15 mL bottle            NDC 0023-9177-15 ALPHAGANP0.1%5 mL in 10 mL bottle              NDC 0023-9321-0510 mL in 10 mL bottle            NDC 0023-9321-1015 mL in 15 mL bottle            NDC 0023-9321-15 0.15%5 mL in 10 mL bottle              NDC 0023-9177-0510 mL in 10 mL bottle            NDC 0023-9177-1015 mL in 15 mL bottle            NDC 0023-9177-15 ALPHAGANP0.1%5 mL in 10 mL bottle              NDC 0023-9321-0510 mL in 10 mL bottle            NDC 0023-9321-1015 mL in 15 mL bottle            NDC 0023-9321-15 0.15%5 mL in 10 mL bottle              NDC 0023-9177-0510 mL in 10 mL bottle            NDC 0023-9177-1015 mL in 15 mL bottle            NDC 0023-9177-15 ALPHAGANP0.1%5 mL in 10 mL bottle              NDC 0023-9321-0510 mL in 10 mL bottle            NDC 0023-9321-1015 mL in 15 mL bottle            NDC 0023-9321-15 0.15%5 mL in 10 mL bottle              NDC 0023-9177-0510 mL in 10 mL bottle            NDC 0023-9177-1015 mL in 15 mL bottle            NDC 0023-9177-15


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

ALPHAGAN

P

Fluorophotometric studies in animals and humans suggest that brimonidine tartrate has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.

Non-Clinical Toxicology
Neonates and infants (under the age of 2 years). ()

Fexmid may have life-threatening interactions with MAO inhibitors (see ).  Postmarketing cases of serotonin syndrome have been reported during combined use of Cyclobenzaprine Hydrochloride and other drugs, such as SSRIs, SNRIs, TCAs, tramadol, bupropion, meperidine, verapamil, or MAO inhibitors. If concomitant treatment with Fexmid and other serotonergic drugs is clinically warranted, careful observation is advised, particularly during treatment initiation or dose increases (see ).

Fexmid may enhance the effects of alcohol, barbiturates, and other CNS depressants.

Tricyclic antidepressants may block the antihypertensive action of guanethidine and similarly acting compounds.

Tricyclic antidepressants may enhance the seizure risk in patients taking tramadol.

____________________________________________________________________ ULTRAM (tramadol HCl tablets, PriCar, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc.) ULTRACET (tramadol HCl and acetaminophen tablets, Ortho-McNeil-Janssen Pharmaceuticals, Inc.)_____________________________________________________________________

ALPHAGAN

P

ALPHAGAN

P

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).