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Triamcinolone Hexacetonide

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Overview

What is Aristospan?

A sterile suspension containing 20 mg/mL of micronized triamcinolone hexacetonide in the following inactive ingredients:

Chemically triamcinolone hexacetonide USP is 9α-Fluoro-11β,16α, 17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-(3,3-dimethylbutyrate). Molecular weight is 532.65. The structural formula is:

The hexacetonide ester of the glucocorticoid triamcinolone is relatively insoluble (0.0002% at 25°C in water).



What does Aristospan look like?



What are the available doses of Aristospan?

Sorry No records found.

What should I talk to my health care provider before I take Aristospan?

Sorry No records found

How should I use Aristospan?

The intra-articular or soft tissue administration of Aristospan (triamcinolone hexacetonide injectable suspension, USP) 20 mg/mL is indicated as adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in acute gouty arthritis, acute and subacute bursitis, acute nonspecific tenosynovitis, epicondylitis, rheumatoid arthritis, synovitis of osteoarthritis.

NOTE: CONTAINS BENZYL ALCOHOL


What interacts with Aristospan?

Sorry No Records found


What are the warnings of Aristospan?

Sorry No Records found


What are the precautions of Aristospan?

Sorry No Records found


What are the side effects of Aristospan?

Sorry No records found


What should I look out for while using Aristospan?

Aristospan is contraindicated in patients who are hypersensitive to any components of this product.

Intramuscular corticosteroid preparations are contraindicated for idiopathic thrombocytopenic purpura.


What might happen if I take too much Aristospan?

Treatment of acute overdosage is by supportive and symptomatic therapy. For chronic overdosage in the face of severe disease requiring continuous steroid therapy, the dosage of the corticosteroid may be reduced only temporarily, or alternate day treatment may be introduced.


How should I store and handle Aristospan?

Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature]. Protect from light. DO NOT FREEZE.Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature]. Protect from light. DO NOT FREEZE.Aristospan® (triamcinolone hexacetonide injectable suspension, USP), 20 mg/mL is available as follows: NDC 0781-3085-71 1 mL fill in a 2 mL vial NDC 0781-3085-75 5 mL fill in a 10 mL vial Aristospan® (triamcinolone hexacetonide injectable suspension, USP), 20 mg/mL is available as follows: NDC 0781-3085-71 1 mL fill in a 2 mL vial NDC 0781-3085-75 5 mL fill in a 10 mL vial Aristospan® (triamcinolone hexacetonide injectable suspension, USP), 20 mg/mL is available as follows: NDC 0781-3085-71 1 mL fill in a 2 mL vial NDC 0781-3085-75 5 mL fill in a 10 mL vial


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract.

Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states.

Their synthetic analogs are primarily used for their anti-inflammatory effects in disorders of many organ systems. When injected intra-articularly, triamcinolone hexacetonide can be expected to be absorbed slowly from the injection site.

Non-Clinical Toxicology
Aristospan is contraindicated in patients who are hypersensitive to any components of this product.

Intramuscular corticosteroid preparations are contraindicated for idiopathic thrombocytopenic purpura.

This product, like many other steroid formulations, is sensitive to heat. Therefore, it should not be autoclaved when it is desirable to sterilize the exterior of the vial.

The lowest possible dose of corticosteroids should be used to control the condition under treatment. When reduction in dosage is possible, the reduction should be gradual.

Since complications of treatment with glucocorticoids are dependent on the size of the dose and the duration of treatment, a risk/benefit decision must be made in each individual case as to dose and duration of treatment and as to whether daily or intermittent therapy should be used.

Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy, most often for chronic conditions. Discontinuation of corticosteroids may result in clinical improvement.

Atrophy at the site of injection has been reported.

(listed alphabetically, under each subsection)

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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