Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate

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Overview

What is Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

Each tablet contains 852 mg dibasic sodium phosphate anhydrous, 155 mg monobasic potassium phosphate, and 130 mg monobasic sodium phosphate monohydrate. Each tablet yields approximately 250 mg of phosphorus, 298 mg of sodium (13.0 mEq) and 45 mg of potassium (1 .1 mEq).

What does Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate look like?

What are the available doses of Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

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What should I talk to my health care provider before I take Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

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How should I use Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

PHOSPHA 250 NEUTRAL increases urinary phosphate and pyrophosphate. As a phosphorus supplement, each tablet supplies 25% of the U.S. Recommended Daily Allowance (U.S. RDA) of phosphorus for adults and children over 4 years of age.

PHOSPHA 250 NEUTRAL tablets should be taken with a full glass of water, with meals and at bedtime.

Adults:

Pediatric patients over 4 years of age:

Pediatric Patients under 4 years of age:

What interacts with Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

This product is contraindicated in patients with infected phosphate stones, in patients with severely impaired renal function (less than 30% of normal) and in the presence of hyperphosphatemia.

What are the warnings of Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

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What are the precautions of Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

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What are the side effects of Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

Gastrointestinal upset (diarrhea, nausea, stomach pain, and vomiting) may occur with phosphate therapy. Also, bone and joint pain (possible phosphate-induced osteomalacia) could occur. The following adverse effects may be observed (primarily from sodium or potassium): headaches; dizziness; mental confusion; seizures; weakness or heaviness of legs; unusual tiredness or weakness; muscle cramps; numbness, tingling, pain or weakness of hands or feet; numbness or tingling around lips; fast or irregular heartbeat; shortness of breath or troubled breathing; swelling of feet or lower legs; unusual weight gain; low urine output; unusual thirst.

To report SUSPECTED ADVERSE REACTIONS, contact Ingenus Pharmaceuticals, LLC at 1-877-748-1970 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

What should I look out for while using Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

This product is contraindicated in patients with infected phosphate stones, in patients with severely impaired renal function (less than 30% of normal) and in the presence of hyperphosphatemia.

What might happen if I take too much Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

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How should I store and handle Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate?

Store at USP controlled room temperature 68°F to 77°F (20°C to 25°C) with excursions permitted between 15°C (59°F) and 30°C (86°F). Contents under pressure. Do not puncture or incinerate. Avoid contact with eyes or other mucous membranes. Keep out of reach of children. White, film-coated, capsule-shaped tablet, debossed with RIS 104 on each tablet.NDC #64980-104-01 Bottles of 100 tabletsWhite, film-coated, capsule-shaped tablet, debossed with RIS 104 on each tablet.NDC #64980-104-01 Bottles of 100 tablets

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Clinical Information

Chemical Structure

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Clinical Pharmacology

Phosphorus has a number of important functions in the biochemistry of the body. The bulk of the body's phosphorus is located in the bones, where it plays a key role in osteoblastic and osteoclastic activities. Enzymatically catalyzed phosphate-transfer reactions are numerous and vital in the metabolism of carbohydrate, lipid and protein, and a proper concentration of the anion is of primary importance in assuring an orderly biochemical sequence. ln addition, phosphorus plays an important role in modifying steady-state tissue concentrations of calcium. Phosphate ions are important buffers of the intracellular fluid, and also play a primary role in the renal excretion of the hydrogen ion.

Oral administration of inorganic phosphates increases serum phosphate levels. Phosphates lower urinary calcium levels in idiopathic hypercalciuria.

In general, in adults, about two thirds of the ingested phosphate in absorbed from the bowel, most of which is rapidly excreted into the urine.

Non-Clinical Toxicology

This product is contraindicated in patients with infected phosphate stones, in patients with severely impaired renal function (less than 30% of normal) and in the presence of hyperphosphatemia.

Gastrointestinal upset (diarrhea, nausea, stomach pain, and vomiting) may occur with phosphate therapy. Also, bone and joint pain (possible phosphate-induced osteomalacia) could occur. The following adverse effects may be observed (primarily from sodium or potassium): headaches; dizziness; mental confusion; seizures; weakness or heaviness of legs; unusual tiredness or weakness; muscle cramps; numbness, tingling, pain or weakness of hands or feet; numbness or tingling around lips; fast or irregular heartbeat; shortness of breath or troubled breathing; swelling of feet or lower legs; unusual weight gain; low urine output; unusual thirst.

To report SUSPECTED ADVERSE REACTIONS, contact Ingenus Pharmaceuticals, LLC at 1-877-748-1970 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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