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Menthol and Capsaicin

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Overview

What is Releevia MC?

Releevia MC Patch contains capsaicin and menthol in a localized dermal delivery system. The capsaicin in Releevia MC is a synthetic equivalent of the naturally occurring compound found in chili peppers. Capsaicin is soluble in alcohol, acetone, and ethyl acetate and very slightly soluble in water. The menthol is slightly soluble in water.

Releevia MC is a single-use patch stored in a foil pouch. Each Releevia MC patch is 8.3 cm x 12.5 cm (104 cm ) and consists of a polyester backing film coated with a drug-containing silicone adhesive mixture, and covered with a removable polyester release liner.

The empirical formula for capsaicin is C H NO , with a molecular weight of 305.42. The chemical compound capsaicin [(E)-8-methyl-N-vanillyl-6-nonenamide] is an activating ligand for transient receptor potential vanilloid 1 receptor (TRPV1) and it has the following structure:

The empirical formula for menthol is C H O, with a molecular weight of 156.27. The chemical compound menthol [(1 ,2 ,5 )-2-isopropyl-5-methylcyclohexanol ] is an activating ligand for transient receptor potential cation channel subfamily M member 8 (TRPM8). It has the following structure:

Each Releevia MC Patch contains 0.0375% capsaicin (0.0375 grams of capsaicin per patch) and 5.00% menthol (5 grams of menthol per patch). The Releevia MC patch contains the following inactive ingredients: Aloe Barbadensis Leaf (Aloe Vera Gel) Juice, Diazolidinyl Urea, EDTA Disodiumm Salt, Glycerin, Iodoproynyl Butylcabamate, Methylparaben, Polysorbate 80, Propylparaben, Sodium Polyacrylate, and Water.



What does Releevia MC look like?



What are the available doses of Releevia MC?

Sorry No records found.

What should I talk to my health care provider before I take Releevia MC?

Sorry No records found

How should I use Releevia MC?

Releevia MC Patch is indicated for the temporary relief of minor aches and muscle pains associated with arthritis, simple backache, strains, muscle soreness and stiffness.

Releevia MC Patch is an external analgesic/counterirritant.

Releevia MC patch contains 0.0375% capsaicin and 5.00% menthol.

Instructions for Use

Directions


What interacts with Releevia MC?

Sorry No Records found


What are the warnings of Releevia MC?

Sorry No Records found


What are the precautions of Releevia MC?

Sorry No Records found


What are the side effects of Releevia MC?

Sorry No records found


What should I look out for while using Releevia MC?

Releevia MC Patch is contraindicated for those patients with a history of hypersensitivity to any of the components of the preparation.


What might happen if I take too much Releevia MC?

Sorry No Records found


How should I store and handle Releevia MC?

Vials should be stored refrigerated at 2-8°C (36-46°F). Vials may be transferred to room temperature storage for a period not to exceed 2 months. Upon transfer, vial cartons must be marked by the dispensing pharmacist with a "DISCARD BY" date (2 months from the transfer date or the labeled expiration date, whichever comes first).Protect from light until administration.Vials should be stored refrigerated at 2-8°C (36-46°F). Vials may be transferred to room temperature storage for a period not to exceed 2 months. Upon transfer, vial cartons must be marked by the dispensing pharmacist with a "DISCARD BY" date (2 months from the transfer date or the labeled expiration date, whichever comes first).Protect from light until administration.Releevia MC Patch is supplied in cartons with either 1 re-sealable pouch containing 5 patches or 3 re-sealable pouches each containing 5 patches each.NDC 69329-030-05 5 Patches per cartonNDC 69329-030-15 15 Patches per cartonStorage: Store below 25°C. Avoid direct sunlight.Manufactured for Patchwerx Labs, Inc. Las Vegas, NV 89118 800-590-8070 Releevia MC Patch is supplied in cartons with either 1 re-sealable pouch containing 5 patches or 3 re-sealable pouches each containing 5 patches each.NDC 69329-030-05 5 Patches per cartonNDC 69329-030-15 15 Patches per cartonStorage: Store below 25°C. Avoid direct sunlight.Manufactured for Patchwerx Labs, Inc. Las Vegas, NV 89118 800-590-8070 Releevia MC Patch is supplied in cartons with either 1 re-sealable pouch containing 5 patches or 3 re-sealable pouches each containing 5 patches each.NDC 69329-030-05 5 Patches per cartonNDC 69329-030-15 15 Patches per cartonStorage: Store below 25°C. Avoid direct sunlight.Manufactured for Patchwerx Labs, Inc. Las Vegas, NV 89118 800-590-8070 Releevia MC Patch is supplied in cartons with either 1 re-sealable pouch containing 5 patches or 3 re-sealable pouches each containing 5 patches each.NDC 69329-030-05 5 Patches per cartonNDC 69329-030-15 15 Patches per cartonStorage: Store below 25°C. Avoid direct sunlight.Manufactured for Patchwerx Labs, Inc. Las Vegas, NV 89118 800-590-8070 Releevia MC Patch is supplied in cartons with either 1 re-sealable pouch containing 5 patches or 3 re-sealable pouches each containing 5 patches each.NDC 69329-030-05 5 Patches per cartonNDC 69329-030-15 15 Patches per cartonStorage: Store below 25°C. Avoid direct sunlight.Manufactured for Patchwerx Labs, Inc. Las Vegas, NV 89118 800-590-8070


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Non-Clinical Toxicology
Releevia MC Patch is contraindicated for those patients with a history of hypersensitivity to any of the components of the preparation.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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