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permethrin
Overview
What is elimite?
ELIMITE (permethrin) 5% Cream is a topical scabicidal agent for the treatment of infestation with (scabies). It is available in an off-white, vanishing cream base. ELIMITE (permethrin) 5% Cream is for topical use only.
Chemical Name
Active Ingredient
Inactive Ingredients
What does elimite look like?
What are the available doses of elimite?
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What should I talk to my health care provider before I take elimite?
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How should I use elimite?
ELIMITE (permethrin) 5% Cream is indicated for the treatment of infestation with (scabies).
Adults and children
ONE APPLICATION IS GENERALLY
CURATIVE.
Patients may experience persistent pruritus after treatment. This is rarely a sign of treatment failure and is not an indication for retreatment. Demonstrable living mites after 14 days indicate that retreatment is necessary.
What interacts with elimite?
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What are the warnings of elimite?
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What are the precautions of elimite?
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What are the side effects of elimite?
Sorry No records found
What should I look out for while using elimite?
ELIMITE (permethrin) 5% Cream is contraindicated in patients with known hypersensitivity to any of its components, to any synthetic pyrethroid or pyrethrin.
If hypersensitivity to ELIMITE (permethrin) 5% Cream occurs, discontinue use.
What might happen if I take too much elimite?
No instance of accidental ingestion of ELIMITE (permethrin) 5% Cream has been reported. If ingested, gastric lavage and general supportive measures should be employed. Excessive topical use (see ) may result in increased irritation and erythema.
How should I store and handle elimite?
Lyophilized powder may be stored refrigerated or at room temperature (3° to 25° C/37° to 77°F). Protect from light. Use immediately after reconstitution. Discard unused material.ELIMITE 5% Cream is available as follows: 60 g tube ( 40076-230-60)
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
Permethrin, a pyrethroid, is active against a broad range of pests including lice, ticks, fleas, mites, and other arthropods. It acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization and paralysis of the pests are the consequences of this disturbance.
Permethrin is rapidly metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in the urine. Although the amount of permethrin absorbed after a single application of the 5% cream has not been determined precisely, data from studies with C-labeled permethrin and absorption studies of the cream applied to patients with moderate to severe scabies indicate it is 2% or less of the amount applied.
Non-Clinical Toxicology
ELIMITE (permethrin) 5% Cream is contraindicated in patients with known hypersensitivity to any of its components, to any synthetic pyrethroid or pyrethrin.If hypersensitivity to ELIMITE (permethrin) 5% Cream occurs, discontinue use.
When administered concurrently, the following drugs may interact with beta-adrenergic receptor blocking agents:
Scabies infestation is often accompanied by pruritus, edema, and erythema. Treatment with ELIMITE (permethrin) 5% Cream may temporarily exacerbate these conditions.
In clinical trials, generally mild and transient burning and stinging followed application with ELIMITE(permethrin) 5% Cream in 10% of patients and was associated with the severity of infestation. Pruritus was reported in 7% of patients at various times post-application. Erythema, numbness, tingling, and rash were reported in 1 to 2% or less of patients (see ). Other adverse events reported since marketing ELIMITE (permethrin) 5% Cream include: headache, fever, dizziness, abdominal pain, diarrhea and nausea and/or vomiting. Although extremely uncommon and not expected when used as directed (see ), rare occurrences of seizure have been reported. None have been medically confirmed as associated with ELIMITE treatment.
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
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