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Adapalene

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Overview

What is Adapalene?

Adapalene cream, 0.1%, contains adapalene 0.1% in an aqueous cream emulsion consisting of carbomer 934P, cyclomethicone, edetate disodium, glycerin, methyl glucose sesquistearate, methylparaben, PEG-20 methyl glucose sesquistearate, phenoxyethanol, propylparaben, purified water, squalane, and trolamine.

The chemical name of adapalene is 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid. It is a white to off-white powder which is soluble in tetrahydrofuran, sparingly soluble in ethanol, and practically insoluble in water. The molecular formula is CHO and molecular weight is 412.52. Adapalene is represented by the following structural formula



What does Adapalene look like?



What are the available doses of Adapalene?

Sorry No records found.

What should I talk to my health care provider before I take Adapalene?

Sorry No records found

How should I use Adapalene?

Adapalene cream is indicated for the topical treatment of acne vulgaris.

Adapalene cream should be applied to affected areas of the skin, once daily at nighttime. A thin film of the cream should be applied to the skin areas where acne lesions appear, using enough to cover the entire affected areas lightly. A mild transitory sensation of warmth or slight stinging may occur shortly after the application of adapalene cream.


What interacts with Adapalene?

Sorry No Records found


What are the warnings of Adapalene?

Sorry No Records found


What are the precautions of Adapalene?

Sorry No Records found


What are the side effects of Adapalene?

Sorry No records found


What should I look out for while using Adapalene?

Adapalene cream should not be administered to individuals who are hypersensitive to adapalene or any of the components in the cream vehicle.


What might happen if I take too much Adapalene?

Adapalene cream is intended for cutaneous use only. If the medication is applied excessively, no more rapid or better results will be obtained and marked redness, scaling, or skin discomfort may occur. The acute oral toxicity of adapalene cream in mice and rats is greater than 10 mL/kg. Chronic ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of Vitamin A.


How should I store and handle Adapalene?

Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].Keep out of reach of children.Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].Keep out of reach of children.Adapalene Cream, 0.1% is supplied in a 45 g tube - NDC 54868-6148-0