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adenosine
Overview
What is Adenoscan?
Adenosine is an endogenous nucleoside and is chemically described as 6-amino-9-beta-D-ribofuranosyl-9-H-purine. Adenosine has the following structural formula:
The molecular formula for adenosine is CHNOand its molecular weight is 267.24.Adenosine is a white crystalline powder. It is soluble in water and practically insoluble in alcohol. Solubility increases by warming and lowering the pH of the solution.
Each Adenoscan vial contains a sterile, non-pyrogenic solution of adenosine 3 mg/mL and sodium chloride 9 mg/mL in water for injection, with pH between 4.5 and 7.5.
What does Adenoscan look like?
What are the available doses of Adenoscan?
For Injection: 3 mg/mL in single-dose vials ()
What should I talk to my health care provider before I take Adenoscan?
How should I use Adenoscan?
Adenoscan (adenosine) is indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately.
The recommended Adenoscan dose is 0.14 mg/kg/min infused over six minutes (total dose of 0.84 mg/kg) ().
Visually inspect Adenoscan for particulate matter and discoloration prior to administration. Do not administer Adenoscan if it contains particulate matter or is discolored.
There are no data on the safety or efficacy of alternative Adenoscan infusion protocols. The safety and efficacy of Adenoscan administered by the intracoronary route have not been established.
The nomogram displayed in was derived from the following general formula:
0.14 (mg/kg/min) x = Infusion rate Adenoscan concentration (mL/min) (3 mg/mL)
What interacts with Adenoscan?
Sorry No Records found
What are the warnings of Adenoscan?
Sorry No Records found
What are the precautions of Adenoscan?
Sorry No Records found
What are the side effects of Adenoscan?
Sorry No records found
What should I look out for while using Adenoscan?
Adenoscan is contraindicated in patients with:
What might happen if I take too much Adenoscan?
The half-life of adenosine is less than 10 seconds and adverse reactions of Adenoscan usually resolve quickly when the infusion is discontinued, although delayed or persistent reactions have been observed. Methylxanthines, such as caffeine, aminophylline, and theophylline, are competitive adenosine receptor antagonists and theophylline has been used to terminate persistent adverse reactions. In clinical trials, theophylline (50-125 mg slow intravenous injection) was used to attenuate Adenoscan adverse reactions in approximately 2% of patients. Methylxanthine use is not recommended in patients who experience seizures in association with Adenoscan.
How should I store and handle Adenoscan?
NDC:64725-0017-1 in a BOTTLE of 100 CAPSULES
