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AK-Con

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Overview

What is AK-Con?

Naphazoline hydrochloride, an ocular vasoconstrictor, is an imidazoline derivative sympathomimetic amine. It occurs as a white, odorless crystalline powder having a bitter taste and is freely soluble in water and in alcohol. The active ingredient is represented by the structural formula:



What does AK-Con look like?



What are the available doses of AK-Con?

Sorry No records found.

What should I talk to my health care provider before I take AK-Con?

Sorry No records found

How should I use AK-Con?

Naphazoline Hydrochloride Ophthalmic Solution is indicated for use as a topical ocular vasoconstrictor.

Instill one or two drops in the conjunctival sac(s) every three to four hours as needed.


What interacts with AK-Con?

Contraindicated in the presence of an anatomically narrow angle or in narrow-angle glaucoma or in persons who have shown hypersensitivity to any component of this preparation.



What are the warnings of AK-Con?

Array


What are the precautions of AK-Con?

General:

For topical ophthalmic use only. Use with caution in the presence of hypertension, cardiovascular abnormalities, hyperglycemia (diabetes), hyperthyroidism, infection or injury.

Patient Information:

Patients should be advised to discontinue the drug and consult a physician if relief is not obtained within 48 hours of therapy, if irritation, blurring or redness persists or increases, or if symptoms of systemic absorption occur, i.e., dizziness, headache, nausea, decrease in body temperature, or drowsiness.

To prevent contaminating the dropper tip and solution, do not touch the eyelids or the surrounding area with the dropper tip of the bottle. If solution changes color or becomes cloudy, do not use.

Drug Interactions:

Concurrent use of maprotiline or tricyclic antidepressants and naphazoline may potentiate the pressor effect of naphazoline. Patients under therapy with MAO inhibitors may experience a severe hypertensive crisis if given a sympathomimetic drug. (See )

Pregnancy:

Pregnancy Category C:

Nursing Mothers:

It is not known whether naphazoline is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when naphazoline is administered to a nursing woman.

Pediatric Use:

Safety and effectiveness in pediatric patients have not been established. See “” and “”


What are the side effects of AK-Con?



Ocular:



Systemic:


What should I look out for while using AK-Con?

Contraindicated in the presence of an anatomically narrow angle or in narrow-angle glaucoma or in persons who have shown hypersensitivity to any component of this preparation.

Patients under therapy with MAO inhibitors may experience a severe hypertensive crisis if given a sympathomimetic drug. Use in children, especially infants, may result in CNS depression leading to coma and marked reduction in body temperature.


What might happen if I take too much AK-Con?

Sorry No Records found


How should I store and handle AK-Con?

ArrayNaphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320Naphazoline Hydrochloride Ophthalmic Solution, USP) is supplied as a sterile 0.1% solution in       15 mL plastic dropper bottles. 17478-216-12Storage:Rx OnlyManufactured by: Akorn Inc.Lake Forest, IL 60045Repackaged by:Rebel Distributors CorpThousand Oaks, CA 91320


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Naphazoline constricts the vascular system of the conjunctiva. It is presumed that this effect is due to direct stimulation of the drug upon the alpha-adrenergic receptors in the arterioles of the conjunctiva, resulting in decreased conjunctival congestion. Naphazoline belongs to the imidazoline class of sympathomimetics.

Non-Clinical Toxicology
Contraindicated in the presence of an anatomically narrow angle or in narrow-angle glaucoma or in persons who have shown hypersensitivity to any component of this preparation.

Patients under therapy with MAO inhibitors may experience a severe hypertensive crisis if given a sympathomimetic drug. Use in children, especially infants, may result in CNS depression leading to coma and marked reduction in body temperature.

Concurrent use of maprotiline or tricyclic antidepressants and naphazoline may potentiate the pressor effect of naphazoline. Patients under therapy with MAO inhibitors may experience a severe hypertensive crisis if given a sympathomimetic drug. (See )

For topical ophthalmic use only. Use with caution in the presence of hypertension, cardiovascular abnormalities, hyperglycemia (diabetes), hyperthyroidism, infection or injury.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Review

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

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