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Tetracaine Hydrochloride

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Overview

What is ALTACAINE?

Tetracaine Hydrochloride 0.5% is a sterile topical ophthalmic solution useful in producing surface anesthesia of the eye. The active ingredient is represented by the structural formula:

Established name:

Tetracaine Hydrochloride

Chemical name:

Benzoic acid, 4-(butylamino)-,2-(dimethylamino)ethyl ester, monohydrochloride

CONTAINS:

Active:

Preservative:

Inactive:



What does ALTACAINE look like?



What are the available doses of ALTACAINE?

Sorry No records found.

What should I talk to my health care provider before I take ALTACAINE?

Sorry No records found

How should I use ALTACAINE?

For procedures in which a rapid and short acting topical ophthalmic anesthetic is indicated such as in tonometry, gonioscopy, removal of corneal foreign bodies, conjunctival scraping for diagnostic purposes, suture removal from the cornea or conjunctiva, other short corneal and conjunctival procedures.

For Tonometry and Other Procedures of Short Duration:

For Minor Surgical Procedures such as Foreign Body or Suture Removal:

For Prolonged Anesthesia as in Cataract Extraction:


What interacts with ALTACAINE?

Sorry No Records found


What are the warnings of ALTACAINE?

Sorry No Records found


What are the precautions of ALTACAINE?

Sorry No Records found


What are the side effects of ALTACAINE?

Sorry No records found


What should I look out for while using ALTACAINE?

Should not be used by the patient without physician supervision, or in those persons showing hypersensitivity to any component of this preparation.

For topical ophthalmic use only. Not for parenteral use. Not for injection. Do not use solution if it contains crystals or if it is cloudy or discolored. Prolonged use results in diminished duration of anesthesia and retarded healing. This may cause the drug to be used more frequently, creating a “vicious circle”. Subsequent corneal infection and/or corneal opacification with accompanying permanent visual loss or corneal perforation may occur. Prolonged use may also produce severe keratitis.


What might happen if I take too much ALTACAINE?

Sorry No Records found


How should I store and handle ALTACAINE?

Store Temozolomide Capsules at 25°C (77°F); excursions permitted to 15°–30°C (59°–86°F) [see USP Controlled Room Temperature].Tetracaine Hydrochloride Ophthalmic Solution, USP 0.5% is supplied in a 15mL size.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Tetracaine Hydrochloride Ophthalmic Solution, USP 0.5% acts by decreasing the permeability of the neuronal membrane, thereby decreasing the flux of sodium, potassium and other ions associated with propagation of the nerve impulse. The onset of anesthesia usually begins within 30 seconds and lasts a relatively short period of time.

Non-Clinical Toxicology
Should not be used by the patient without physician supervision, or in those persons showing hypersensitivity to any component of this preparation.

For topical ophthalmic use only. Not for parenteral use. Not for injection. Do not use solution if it contains crystals or if it is cloudy or discolored. Prolonged use results in diminished duration of anesthesia and retarded healing. This may cause the drug to be used more frequently, creating a “vicious circle”. Subsequent corneal infection and/or corneal opacification with accompanying permanent visual loss or corneal perforation may occur. Prolonged use may also produce severe keratitis.

Additive adverse effects resulting from cholinergic blockade may occur when hyoscyamine sulfate is administered concomitantly with other antimuscarinics, amantadine, haloperidol, phenothiazines, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants or some antihistamines.

Antacids may interfere with the absorption of hyoscyamine sulfate. Administer Hyoscyamine Sulfate Orally Disintegrating Tablets before meals; antacids after meals.

Do not touch dropper tip to any surface as this may contaminate the solution. As with all anesthetics, continuous and prolonged use should be avoided. Protection of the eye from irritating chemicals, foreign bodies and rubbing during the period of anesthesia is very important. Tetracaine Hydrochloride Ophthalmic Solution, USP 0.5% should be used cautiously in patients with known allergy or cardiac disease. If signs of sensitivity develop during the treatment or irritation persists or increases, patients should be advised to discontinue use and consult prescribing physician.

Transient symptoms (signs) such as stinging, burning and conjunctival redness may occur. A rare, severe, immediate type allergic corneal reaction has been reported characterized by acute diffuse epithelial keratitis with filament formation and/or sloughing of large areas of necrotic epithelium, diffuse stromal edema, descemetitis and iritis.

To Report SUSPECTED ADVERSE REACTIONS, contact Altaire Pharmaceuticals, Inc., at 631-722-5988 or 1-800-258-2471, 9am - 5pm EST Monday – Friday, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.  

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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