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levonorgestrel/ethinyl estradiol and ethinyl estradiol
Overview
What is Amethia Lo?
Levonorgestrel/ethinyl estradiol and ethinyl estradiol tablets provide an oral contraceptive regimen of 84 white tablets each containing 0.1 mg levonorgestrel and 0.02 mg ethinyl estradiol, followed by 7 blue tablets each containing 0.01 mg ethinyl estradiol.
The structural formulas for the active components are:
Levonorgestrel is chemically 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-, (-)-.
Ethinyl Estradiol is 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17 α)-.
Inactive ingredients
Inactive ingredients
What does Amethia Lo look like?
What are the available doses of Amethia Lo?
AMETHIA Lo tablets consist of 84 white tablets containing 0.1 mg levonorgestrel and 0.02 mg ethinyl estradiol, and 7 blue tablets containing 0.01 mg ethinyl estradiol. ()
What should I talk to my health care provider before I take Amethia Lo?
How should I use Amethia Lo?
AMETHIA Lo tablets are indicated for use by women to prevent pregnancy.
Take one tablet by mouth at the same time every day. The dosage of AMETHIA Lo tablets is one white tablet containing levonorgestrel and ethinyl estradiol daily for 84 consecutive days, followed by one blue ethinyl estradiol tablet for 7 days. To achieve maximum contraceptive effectiveness, AMETHIA Lo tablets must be taken exactly as directed and at intervals not exceeding 24 hours.
Instruct the patient to begin taking AMETHIA Lo tablets on the first Sunday after the onset of menstruation. If menstruation begins on a Sunday, the first white tablet is taken that day. One white tablet should be taken daily for 84 consecutive days, followed by one blue tablet for 7 consecutive days. A non-hormonal back-up method of contraception (such as condoms or spermicide) should be used until a white tablet has been taken daily for 7 consecutive days. A scheduled period should occur during the 7 days that the blue tablets are taken.
Begin the next and all subsequent 91-day cycles without interruption on the same day of the week (Sunday) on which the patient began her first dose of AMETHIA Lo tablets, following the same schedule: 84 days taking a white tablet followed by 7 days taking a blue tablet. If the patient does not immediately start her next pill pack, she should protect herself from pregnancy by using a non-hormonal back-up method of contraception until she has taken a white tablet daily for 7 consecutive days.
If unscheduled spotting or bleeding occurs, instruct the patient to continue on the same regimen. If the bleeding is persistent or prolonged, advise the patient to consult her healthcare provider.
For patient instructions regarding missed pills,
For postpartum women who are not breastfeeding, start AMETHIA Lo tablets no earlier than four to six weeks postpartum. If the patient starts on AMETHIA Lo tablets postpartum and has not yet had a period, evaluate for possible pregnancy, and instruct her to use an additional method of contraception until she has taken a white tablet for 7 consecutive days.
What interacts with Amethia Lo?
Sorry No Records found
What are the warnings of Amethia Lo?
Sorry No Records found
What are the precautions of Amethia Lo?
Sorry No Records found
What are the side effects of Amethia Lo?
Sorry No records found
What should I look out for while using Amethia Lo?
Do not prescribe AMETHIA Lo tablets to women who are known to have the following conditions:
Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs should not be used by women who are over 35 years of age and smoke.
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What might happen if I take too much Amethia Lo?
There have been no reports of serious ill effects from overdose, including ingestion by children. Overdosage may cause withdrawal bleeding in females and nausea.
How should I store and handle Amethia Lo?
Sorry No Records found
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
Combination OCs lower the risk of becoming pregnant primarily by suppressing ovulation. Other possible mechanisms may include cervical mucus changes that inhibit sperm penetration and endometrial changes that reduce the likelihood of implantation.
Non-Clinical Toxicology
Do not prescribe AMETHIA Lo tablets to women who are known to have the following conditions:Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs should not be used by women who are over 35 years of age and smoke.
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Stop COCs if an arterial or deep venous thrombotic event occurs. Although use of COCs increases the risk of venous thromboembolism, pregnancy increases the risk of venous thromboembolism as much or more than the use of COCs. The risk of venous thromboembolism in women using COCs is 3 to 9 per 10,000 woman-years. Use of COCs also increases the risk of arterial thromboses such as strokes and myocardial infarctions, especially in women with other risk factors for these events.
Use of AMETHIA Lo tablets provides women with more hormonal exposure on a yearly basis than conventional monthly oral contraceptives containing the same strength synthetic estrogens and progestins (an additional 9 and 13 weeks of exposure to progestin and estrogen, respectively, per year.)
If feasible, stop COCs at least 4 weeks before and through 2 weeks after major surgery or other surgeries known to have an elevated risk of thromboembolism.
Start COCs no earlier than 4 weeks after delivery, in women who are not breastfeeding. The risk of postpartum thromboembolism decreases after the third postpartum week, whereas the risk of ovulation increases after the third postpartum week.
Stop COCs if there is unexplained loss of vision, proptosis, diplopia, papilledema, or retinal vascular lesions. Evaluate for retinal vein thrombosis immediately.
The following serious adverse reactions with the use of COCs are discussed elsewhere in the labeling:
Adverse reactions commonly reported by COC users are:
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
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