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AMMONIA N-13

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Overview

What is AMMONIA N-13?



What does AMMONIA N-13 look like?



What are the available doses of AMMONIA N-13?

Glass vial containing 0.139-9.620 GBq (3.75-260 mCi/mL) of Ammonia N 13 Injection in aqueous 0.9% sodium chloride solution (approximately 5 mL volume) ().

What should I talk to my health care provider before I take AMMONIA N-13?

How should I use AMMONIA N-13?

Ammonia N 13 Injection is indicated for diagnostic Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease.

Aseptically withdraw Ammonia N 13 Injection from its container and administer 10-20 mCi (0.368 - 0.736 GBq) as a bolos through a catheter inserted into a large peripheral vein.

Start imaging 3 minutes after the injection and acquire images for a total of 10-20 minutes.


What interacts with AMMONIA N-13?

Sorry No Records found


What are the warnings of AMMONIA N-13?

Sorry No Records found


What are the precautions of AMMONIA N-13?

Sorry No Records found


What are the side effects of AMMONIA N-13?

Sorry No records found


What should I look out for while using AMMONIA N-13?

None


What might happen if I take too much AMMONIA N-13?

Sorry No Records found


How should I store and handle AMMONIA N-13?

Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature].Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.A Schedule CII Narcotic.Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature].Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.A Schedule CII Narcotic.Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature].Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.A Schedule CII Narcotic.Ammonia N 13 Injection is packaged in 30 or 50 mL multiple dose vials containing between 1.11 GBq to 48.1 GBq (30 mCi to 1300 mCi) of [N] ammonia, at the end of synthesis (EOS) reference time, in 0.9% sodium chloride injection solution. The recommended dose of radioactivity (10-20 mCi, 370-740 MBq) is associated with a theoretical mass dose of 0.5-1.0 picomoles (8.47- 16.94 picograms) of Ammonia. NDC� Code:30 mL Vial:����������� NDC 52768-100-3050 mL Vial:����������� NDC 52768-100-50 This radiopharmaceutical is licensed by the State of Tennessee, Department of Environment and Conservation, for distribution to entities licensed pursuant to chapter 1200-02-07 Division of Radiological Health Regulations or under the equivalent licenses of an Agreement State or Licensing State.Ammonia N 13 Injection is packaged in 30 or 50 mL multiple dose vials containing between 1.11 GBq to 48.1 GBq (30 mCi to 1300 mCi) of [N] ammonia, at the end of synthesis (EOS) reference time, in 0.9% sodium chloride injection solution. The recommended dose of radioactivity (10-20 mCi, 370-740 MBq) is associated with a theoretical mass dose of 0.5-1.0 picomoles (8.47- 16.94 picograms) of Ammonia. NDC� Code:30 mL Vial:����������� NDC 52768-100-3050 mL Vial:����������� NDC 52768-100-50 This radiopharmaceutical is licensed by the State of Tennessee, Department of Environment and Conservation, for distribution to entities licensed pursuant to chapter 1200-02-07 Division of Radiological Health Regulations or under the equivalent licenses of an Agreement State or Licensing State.Ammonia N 13 Injection is packaged in 30 or 50 mL multiple dose vials containing between 1.11 GBq to 48.1 GBq (30 mCi to 1300 mCi) of [N] ammonia, at the end of synthesis (EOS) reference time, in 0.9% sodium chloride injection solution. The recommended dose of radioactivity (10-20 mCi, 370-740 MBq) is associated with a theoretical mass dose of 0.5-1.0 picomoles (8.47- 16.94 picograms) of Ammonia. NDC� Code:30 mL Vial:����������� NDC 52768-100-3050 mL Vial:����������� NDC 52768-100-50 This radiopharmaceutical is licensed by the State of Tennessee, Department of Environment and Conservation, for distribution to entities licensed pursuant to chapter 1200-02-07 Division of Radiological Health Regulations or under the equivalent licenses of an Agreement State or Licensing State.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Ammonia N 13 Injection is a radiolabeled analog of ammonia that is distributed to all organs of the body after intravenous administration. It is extracted from the blood in the coronary capillaries into the myocardial cells where it is metabolized to glutamine N 13 and retained in the cells. The presence of ammonia N 13 and glutamine N 13 in the myocardium allows for PET imaging of the myocardium.

Non-Clinical Toxicology
None

Drug Interactions

The use of MAO inhibitors or tricyclic antidepressants with hydrocodone preparations may increase the effect of either the antidepressant or hydrocodone.

No adverse reactions have been reported for Ammonia N 13 Injection based on a review of the published literature, publicly available reference sources, and adverse drug reaction reporting systems. However, the completeness of these sources is not known.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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