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BAVENCIO

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Overview

What is BAVENCIO?

Avelumab is a programmed death ligand-1 (PD-L1) blocking antibody. Avelumab is a human IgG1 lambda monoclonal antibody that has a molecular weight of approximately 147 kDa.

BAVENCIO (avelumab) Injection for intravenous use is a sterile, preservative-free, non-pyrogenic, clear, colorless to slightly yellow solution. Each single-dose vial contains 200 mg avelumab in 10 mL (20 mg/mL). Each mL contains 20 mg avelumab, D-mannitol (51 mg), glacial acetic acid (0.6 mg), polysorbate 20 (0.5 mg), sodium hydroxide (0.3 mg), and Water for Injection. The pH range of the solution is 5.0 – 5.6.



What does BAVENCIO look like?



What are the available doses of BAVENCIO?

Injection: 200 mg/10 mL (20 mg/mL) solution in single-dose vial. ()

What should I talk to my health care provider before I take BAVENCIO?

Lactation: Advise not to breastfeed. ()

How should I use BAVENCIO?

BAVENCIO (avelumab) is indicated for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC).

This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials .

Premedicate patients with an antihistamine and with acetaminophen prior to the first 4 infusions of BAVENCIO. Premedication should be administered for subsequent BAVENCIO doses based upon clinical judgment and presence/severity of prior infusion reactions


What interacts with BAVENCIO?

Sorry No Records found


What are the warnings of BAVENCIO?

Sorry No Records found


What are the precautions of BAVENCIO?

Sorry No Records found


What are the side effects of BAVENCIO?

Sorry No records found


What should I look out for while using BAVENCIO?

None.


What might happen if I take too much BAVENCIO?

No information on BAVENCIO overdosage is available.


How should I store and handle BAVENCIO?

BAVENCIO (avelumab) Injection is a sterile, preservative-free, and clear, colorless to slightly yellow solution for intravenous infusion supplied as a single-dose vial of 200 mg/10 mL (20 mg/mL), individually packed into a carton (NDC 44087-3535-1).