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bepotastine besilate

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Overview

What is Bepreve?

BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is a sterile, topically administered drug for ophthalmic use. Each mL of BEPREVE contains 15 mg bepotastine besilate. Bepotastine besilate is designated chemically as (+) -4-[[(S)-p-chloro-alpha -2-pyridylbenzyl]oxy]-1- piperidine butyric acid monobenzenesulfonate. The chemical structure for bepotastine besilate is:

Bepotastine besilate is a white or pale yellowish crystalline powder. The molecular weight of bepotastine besilate is 547.06 daltons. BEPREVE ophthalmic solution is supplied as a sterile, aqueous 1.5% solution, with a pH of 6.8. The osmolality of BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is approximately

290 mOsm/kg.

Each mL of BEPREVE (bepotastine besilate ophthalmic solution) 1.5% contains:



What does Bepreve look like?



What are the available doses of Bepreve?

Ophthalmic solution containing bepotastine besilate, 15 mg/mL (1.5%). ()

What should I talk to my health care provider before I take Bepreve?

How should I use Bepreve?

BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is a histamine H receptor antagonist indicated for the treatment of itching associated with signs and symptoms of allergic conjunctivitis.

Instill one drop of BEPREVE into the affected eye(s) twice a day.Remove contact lenses prior to instillation of BEPREVE.


What interacts with Bepreve?

Sorry No Records found


What are the warnings of Bepreve?

Sorry No Records found


What are the precautions of Bepreve?

Sorry No Records found


What are the side effects of Bepreve?

Sorry No records found


What should I look out for while using Bepreve?

BEPREVE is contraindicated in patients with a history of hypersensitivity reactions to bepotastine or any of the other ingredients .


What might happen if I take too much Bepreve?

Sorry No Records found


How should I store and handle Bepreve?

Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. Keep tightly closed (protect from moisture). Protect from light. BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is supplied in a white low density polyethylene plastic squeeze bottle with a white controlled dropper tip and a white polypropylene cap in the following size:5 mL (NDC 24208-629-02) 10 mL (NDC 24208-629-01)STORAGEStore at 15°C to 25°C (59°F to 77°F).BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is supplied in a white low density polyethylene plastic squeeze bottle with a white controlled dropper tip and a white polypropylene cap in the following size:5 mL (NDC 24208-629-02) 10 mL (NDC 24208-629-01)STORAGEStore at 15°C to 25°C (59°F to 77°F).BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is supplied in a white low density polyethylene plastic squeeze bottle with a white controlled dropper tip and a white polypropylene cap in the following size:5 mL (NDC 24208-629-02) 10 mL (NDC 24208-629-01)STORAGEStore at 15°C to 25°C (59°F to 77°F).BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is supplied in a white low density polyethylene plastic squeeze bottle with a white controlled dropper tip and a white polypropylene cap in the following size:5 mL (NDC 24208-629-02) 10 mL (NDC 24208-629-01)STORAGEStore at 15°C to 25°C (59°F to 77°F).BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is supplied in a white low density polyethylene plastic squeeze bottle with a white controlled dropper tip and a white polypropylene cap in the following size:5 mL (NDC 24208-629-02) 10 mL (NDC 24208-629-01)STORAGEStore at 15°C to 25°C (59°F to 77°F).


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Bepotastine is a topically active, direct H1-receptor antagonist and an inhibitor of the release of histamine from mast cells.

Non-Clinical Toxicology
BEPREVE is contraindicated in patients with a history of hypersensitivity reactions to bepotastine or any of the other ingredients .





Isoniazid should not be administered with food. Studies have shown that the bioavailability of isoniazid is reduced significantly when administered with food. Tyramine- and histamine-containing foods should be avoided in patients receiving isoniazid. Because isoniazid has some monoamine oxidase inhibiting activity, an interaction with tyramine-containing foods (cheese, red wine) may occur. Diamine oxidase may also be inhibited, causing exaggerated response (e.g., headache, sweating, palpitations, flushing, hypotension) to foods containing histamine (e.g., skipjack, tuna, other tropical fish).

To minimize contaminating the dropper tip and solution, advise the patient not to touch the eyelids or surrounding areas with the dropper tip of the bottle and to keep the bottle tightly closed when not in use.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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