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Betadine

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Overview

What is Betadine?

Povidone-Iodine is a broad-spectrum microbicide with the chemical formulas:

2-pyrrolidinone, 1- ethenyl-, homopolymer, compound with iodine; 1-vinyl-2-pyrrolidinone polymer, compound with iodine. The structural formula is as follows:

BETADINE* 5% Sterile Ophthalmic Prep Solution contains 5% povidone-iodine (0.5% available iodine) as a sterile dark brown solution stabilized by glycerin. Inactive Ingredients: purified water, citric acid, glycerin, nonoxynol-9, sodium chloride, sodium hydroxide, and dibasic sodium phosphate.



What does Betadine look like?



What are the available doses of Betadine?

Sorry No records found.

What should I talk to my health care provider before I take Betadine?

Sorry No records found

How should I use Betadine?

BETADINE* 5% Sterile Ophthalmic Prep Solution for the eye is indicated for prepping of the periocular region (lids, brow, and cheek) and irrigation of the ocular surface (cornea, conjunctiva, and palpebral fornices).

While the inner surface and contents of the immediate container (i.e. bottle) are sterile, the outer surface of the bottle is not sterile. The use of the bottle in a sterile field should be avoided.

BETADINE* 5% Sterile Ophthalmic Prep Solution is used as follows:


What interacts with Betadine?

Sorry No Records found


What are the warnings of Betadine?

Sorry No Records found


What are the precautions of Betadine?

Sorry No Records found


What are the side effects of Betadine?

Sorry No records found


What should I look out for while using Betadine?

Do not use on individuals known to be sensitive to iodine, or other components of this product.

FOR EXTERNAL USE ONLY. NOT FOR INTRAOCULAR INJECTION OR IRRIGATION.


What might happen if I take too much Betadine?

Sorry No Records found


How should I store and handle Betadine?

StorageStore Pantoprazole Sodium Delayed-Release Tablets, USP at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) []. StorageStore Pantoprazole Sodium Delayed-Release Tablets, USP at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) []. BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014BETADINE* 5% Sterile Ophthalmic Prep Solution is packaged under sterile conditions and supplied in 1 fl OZ (30 mL) form sealed blue HDPE bottles. Twenty-four (24) bottles are packed in each shipper.NDC 0065-0411-30 Store at 15-25°C (59-77°F).Rx OnlySingle use only       Manufactured for:Alcon Laboratories, Inc.6201 South FreewayFort Worth, TX 76134 Manufactured by:Catalent Pharma Solutions, LLCWoodstock, IL 60098 *BETADINE is a registered trademark of Purdue Products L.P.       9008808-1014


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

A placebo-controlled study in 38 normal volunteers yielded data for 36 subjects who showed a mean log reduction of 3.05 log units in total aerobes at 10 minutes following prepping the skin with BETADINE* 5% Sterile Ophthalmic Prep Solution compared with reduction of 1.58 log units after prepping with vehicle free of the iodine complex. This placebo-controlled study indicates a mean log reduction by the iodine complex compared with the control solution of 1.47 log units at 10 minutes and 1.79 log units at 45 minutes. The base-line mean aerobic bacterial count was 7,586 organisms per square cm.

Non-Clinical Toxicology
Do not use on individuals known to be sensitive to iodine, or other components of this product.

FOR EXTERNAL USE ONLY. NOT FOR INTRAOCULAR INJECTION OR IRRIGATION.

HMG-CoA reductase inhibitors:

Co-administration of multiple doses of 10 mg of verapamil with 80 mg simvastatin resulted in exposure to simvastatin 2.5-fold that following simvastatin alone. Limit the dose of simvastatin in patients on verapamil to 10 mg daily. Limit the daily dose of lovastatin to 40 mg. Lower starting and maintenance doses of other CYP3A4 substrates (e.g., atorvastatin) may be required as verapamil may increase the plasma concentration of these drugs.

Beta-blockers:

Asymptomatic bradycardia (36 beats/min) with a wandering atrial pacemaker has been observed in a patient receiving concomitant timolol (a beta-adrenergic blocker) eyedrops and oral verapamil.

A decrease in metoprolol and propranolol clearance has been observed when either drug is administered concomitantly with verapamil. A variable effect has been seen when verapamil and atenolol were given together.

Digitalis

Antihypertensive agents

Antiarrhythmic agents:













The electrophysiologic effects of quinidine and verapamil on AV conduction were studied in 8 patients. Verapamil significantly counteracted the effects of quinidine on AV conduction. There has been a report of increased quinidine levels during verapamil therapy.

Other agents:

























































No studies are available in patients with thyroid disorders; therefore, caution is advised in using BETADINE* 5% Sterile Ophthalmic Prep Solution in these patients due to the possibility of iodine absorption.

Local sensitivity has been exhibited by some individuals to povidone-iodine ophthalmic solution.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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