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Byetta
Overview
What is Byetta?
BYETTA (exenatide) is a synthetic peptide that was originally identified in the lizard Exenatide differs in chemical structure and pharmacological action from insulin, sulfonylureas (including D-phenylalanine derivatives and meglitinides), biguanides, thiazolidinediones, alpha-glucosidase inhibitors, amylinomimetics and dipeptidyl peptidase-4 inhibitors.
Exenatide is a 39-amino acid peptide amide. Exenatide has the empirical formula CHNOS and molecular weight of 4186.6 Daltons. The amino acid sequence for exenatide is shown below.
H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH
BYETTA is supplied for SC injection as a sterile, preserved isotonic solution in a glass cartridge that has been assembled in a pen-injector (pen). Each milliliter (mL) contains 250 micrograms (mcg) synthetic exenatide, 2.2 mg metacresol as an antimicrobial preservative, mannitol as a tonicity-adjusting agent, and glacial acetic acid and sodium acetate trihydrate in water for injection as a buffering solution at pH 4.5. Two prefilled pens are available to deliver unit doses of 5 mcg or 10 mcg. Each prefilled pen will deliver 60 doses to provide for 30 days of twice daily administration (BID).
What does Byetta look like?
What are the available doses of Byetta?
BYETTA is supplied as 250 mcg/mL exenatide in:
What should I talk to my health care provider before I take Byetta?
How should I use Byetta?
BYETTA (exenatide) is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see ].
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2.1
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2.1
What interacts with Byetta?
Sorry No Records found
What are the warnings of Byetta?
Sorry No Records found
What are the precautions of Byetta?
Sorry No Records found
What are the side effects of Byetta?
Sorry No records found
What should I look out for while using Byetta?
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4.1
What might happen if I take too much Byetta?
In a clinical study of BYETTA, three patients with type 2 diabetes each experienced a single overdose of 100 mcg SC (10 times the maximum recommended dose). Effects of the overdoses included severe nausea, severe vomiting, and rapidly declining blood glucose concentrations. One of the three patients experienced severe hypoglycemia requiring parenteral glucose administration. The three patients recovered without complication. In the event of overdose, appropriate supportive treatment should be initiated according to the patient's clinical signs and symptoms.
How should I store and handle Byetta?
Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:Pioglitazone Tablets, USP are available containing pioglitazone hydrochloride, USP equivalent to 15 mg, 30 mg or 45 mg of pioglitazone base. The 15 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0048-93bottles of 30 tabletsNDC 0378-0048-77bottles of 90 tabletsNDC 0378-0048-05bottles of 500 tablets The 30 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0228-93bottles of 30 tabletsNDC 0378-0228-77bottles of 90 tabletsNDC 0378-0228-05bottles of 500 tabletsThe 45 mg tablets are white to off-white, round, unscored tablets debossed with over on one side of the tablet and blank on the other side. They are available as follows:NDC 0378-0318-93bottles of 30 tabletsNDC 0378-0318-77bottles of 90 tabletsNDC 0378-0318-05bottles of 500 tabletsStorage:Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.PHARMACIST:
