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CENTANY

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Overview

What is CENTANY?

Each gram of Centany (mupirocin ointment),2% contains 20 mg mupirocin in a soft white ointment base consisting of castor oil, oleyl alcohol, hard fat (Softisan 378) and propylene glycol monostearate. Mupirocin is a naturally occurring antibiotic. The chemical name is (E)-(2S,3,4,5)-5-[(2,3,4,5)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2 -pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid. The molecular formula of mupirocin is CHO and the molecular weight is 500.63. The chemical structure is:



What does CENTANY look like?



What are the available doses of CENTANY?

Sorry No records found.

What should I talk to my health care provider before I take CENTANY?

Sorry No records found

How should I use CENTANY?

Centany (mupirocin ointment),2% is indicated for the topical treatment of impetigo due to: and .

A small amount of Centany (mupirocin ointment),2% should be applied to the affected area three times daily. The area treated may be covered with a gauze dressing if desired. Patients not showing a clinical response within 3 to 5 days should be re-evaluated.


What interacts with CENTANY?

This drug is contraindicated in individuals with a history of sensitivity reactions to any of its components.



What are the warnings of CENTANY?

DEMADEX should be used with caution in patients with hepatic disease with cirrhosis and ascites, since sudden alterations of fluid and electrolyte balance may precipitate hepatic coma. In these patients, diuresis with DEMADEX (or any other diuretic) is best initiated in the hospital. To prevent hypokalemia and metabolic alkalosis, an aldosterone antagonist or potassium-sparing drug should be used concomitantly with DEMADEX.


What are the precautions of CENTANY?

If a reaction suggesting sensitivity or chemical irritation should occur with the use of Centany (mupirocin ointment),2%, treatment should be discontinued and appropriate alternative therapy for the infection instituted.

As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. Centany (mupirocin ointment),2% is not formulated for use on mucosal surfaces. Centany (mupirocin ointment),2% is not intended for nasal use.

Information for Patients:

Drug Interactions:

Carcinogenesis, Mutagenesis, Impairment of Fertility:

Results of the following studies performed with mupirocin calcium or mupirocin sodium and did not indicate a potential for genotoxicity: rat primary hepatocyte unscheduled DNA synthesis, sediment analysis for DNA strand breaks, reversion test (Ames), mutation assay, metaphase analysis of human lymphocytes, mouse lymphoma assay, and bone marrow micronuclei assay in mice.

Reproduction studies were performed in male and female rats with mupirocin administered subcutaneously at doses up to 14 times the human topical dose (approximately 60 mg mupirocin/ day) on a mg/m basis and revealed neither evidence of impaired fertility nor impaired reproductive performance attributable to mupirocin.

Pregnancy

Nursing Mothers:

Pediatric Use:


What are the side effects of CENTANY?

The following local adverse reactions have been reported in connection with the use of Centany (mupirocin ointment),2%; application site reactions and pruritus, each in 1% of patients; contact dermatitis and furunculosis, each in 0.7% of patients; and exfoliative dermatitis and rash, each in 0.3% of patients.


What should I look out for while using CENTANY?

This drug is contraindicated in individuals with a history of sensitivity reactions to any of its components.

Centany (mupirocin ointment),2% is not for ophthalmic use.


What might happen if I take too much CENTANY?

Sorry No Records found


How should I store and handle CENTANY?

Store below 30°C (86°F).Manufactured by:DANBURY PHARMACAL, INC.Danbury, CT 06810Store below 30°C (86°F).Manufactured by:DANBURY PHARMACAL, INC.Danbury, CT 06810Centany (mupirocin ointment),2% is supplied in 15 gram (NDC 0062-1610-01) and 30 gram (NDC 0062-1610-03) tubes.Store at controlled room temperature 20° to 25°C (68° to 77°F).OrthoNeutrogenaDistributed by: OrthoNeutrogena, Division of Ortho-McNeil Pharmaceutical, Inc.Skillman, New Jersey 08558©OMP 2004Rev: April 2004Printed in USA635-10-686-3U.S. Patent No. 6,013,657Centany (mupirocin ointment),2% is supplied in 15 gram (NDC 0062-1610-01) and 30 gram (NDC 0062-1610-03) tubes.Store at controlled room temperature 20° to 25°C (68° to 77°F).OrthoNeutrogenaDistributed by: OrthoNeutrogena, Division of Ortho-McNeil Pharmaceutical, Inc.Skillman, New Jersey 08558©OMP 2004Rev: April 2004Printed in USA635-10-686-3U.S. Patent No. 6,013,657Centany (mupirocin ointment),2% is supplied in 15 gram (NDC 0062-1610-01) and 30 gram (NDC 0062-1610-03) tubes.Store at controlled room temperature 20° to 25°C (68° to 77°F).OrthoNeutrogenaDistributed by: OrthoNeutrogena, Division of Ortho-McNeil Pharmaceutical, Inc.Skillman, New Jersey 08558©OMP 2004Rev: April 2004Printed in USA635-10-686-3U.S. Patent No. 6,013,657Centany (mupirocin ointment),2% is supplied in 15 gram (NDC 0062-1610-01) and 30 gram (NDC 0062-1610-03) tubes.Store at controlled room temperature 20° to 25°C (68° to 77°F).OrthoNeutrogenaDistributed by: OrthoNeutrogena, Division of Ortho-McNeil Pharmaceutical, Inc.Skillman, New Jersey 08558©OMP 2004Rev: April 2004Printed in USA635-10-686-3U.S. Patent No. 6,013,657


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Following the application of Centany (mupirocin ointment),2% to a 400 cm area on the back of 23 healthy volunteers once daily for 7 days, the mean (range) cumulative urinary excretion of monic acid over 24 hrs following the last administration was 1.25% (0.2% to 3.0%) of the administered dose of mupirocin. The monic acid concentration in urine collected at specified intervals for 24 hrs on Day 7 ranged from <0.050 to 0.637 μg/mL.

Non-Clinical Toxicology
This drug is contraindicated in individuals with a history of sensitivity reactions to any of its components.

Centany (mupirocin ointment),2% is not for ophthalmic use.

Drug Interactions:

If a reaction suggesting sensitivity or chemical irritation should occur with the use of Centany (mupirocin ointment),2%, treatment should be discontinued and appropriate alternative therapy for the infection instituted.

As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. Centany (mupirocin ointment),2% is not formulated for use on mucosal surfaces. Centany (mupirocin ointment),2% is not intended for nasal use.

The following local adverse reactions have been reported in connection with the use of Centany (mupirocin ointment),2%; application site reactions and pruritus, each in 1% of patients; contact dermatitis and furunculosis, each in 0.7% of patients; and exfoliative dermatitis and rash, each in 0.3% of patients.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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