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Cyclogyl

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Overview

What is Cyclogyl?

CYCLOGYL® (cyclopentolate hydrochloride ophthalmic solution, USP) is an anticholinergic prepared as a sterile, borate buffered, solution for topical ocular use. It is supplied in three strengths. The active ingredient is represented by the structural formula:

Molecular Weight=327.85

Molecular Formula: CHNO•HCl

Established name: Cyclopentolate Hydrochloride

Chemical name: 2-(Dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate hydrochloride

Each mL contains: Active:

Preservative:

Inactives:



What does Cyclogyl look like?



What are the available doses of Cyclogyl?

Sorry No records found.

What should I talk to my health care provider before I take Cyclogyl?

Sorry No records found

How should I use Cyclogyl?

Cyclopentolate hydrochloride is used to produce mydriasis and cycloplegia.

Adults:

Children:

Small Infants:


What interacts with Cyclogyl?

Sorry No Records found


What are the warnings of Cyclogyl?

Sorry No Records found


What are the precautions of Cyclogyl?

Sorry No Records found


What are the side effects of Cyclogyl?

Sorry No records found


What should I look out for while using Cyclogyl?

Should not be used when untreated narrow-angle glaucoma, or untreated anatomically narrow angles are present, or if the patient is hypersensitive to any component of this preparation.

FOR TOPICAL OPHTHALMIC USE ONLYNOT FOR INJECTION. This preparation may cause CNS disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate. To minimize absorption, use only 1 drop of 0.5% CYCLOGYL solution per eye, followed by pressure applied over the nasolacrimal sac for two to three minutes. Observe infants closely for at least 30 minutes following instillation.

Mydriatics may produce a transient elevation of intraocular pressure.


What might happen if I take too much Cyclogyl?

Excessive dosage may produce behavioral disturbances, tachycardia, hyperpyrexia, hypertension, elevated intraocular pressure, vasodilation, urinary retention, diminished gastrointestinal motility and decreased secretion in salivary and sweat glands, pharynx, bronchi and nasal passages. Patients exhibiting signs of overdosage should receive supportive care and monitoring.


How should I store and handle Cyclogyl?

In multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx OnlyIn multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx OnlyIn multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx OnlyIn multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx OnlyIn multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx OnlyIn multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx OnlyIn multiple-dose plastic DROP-TAINER® dispensers:      0.5% CYCLOGYL                  1% CYCLOGYL                    2% CYCLOGYL15 mL NDC 0065-0395-15    2 mL NDC 0065-0396-02      2 mL NDC 0065-0397-02                                                5 mL NDC 0065-0396-05      5 mL NDC 0065-0397-05                                              15 mL NDC 0065-0396-15    15 mL NDC 0065-0397-15 Storage: Rx Only


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

This anticholinergic preparation blocks the responses of the sphincter muscle of the iris and the accommodative muscle of the ciliary body to cholinergic stimulation, producing papillary dilation (mydriasis) and paralysis of accommodation (cycloplegia). It acts rapidly, but has a shorter duration than atropine. Maximal cycloplegia occurs within 25 to 75 minutes after instillation. Complete recovery of accommodation usually takes 6 to 24 hours. Complete recovery from mydriasis in some individuals may require several days. Heavily pigmented irides may require more doses than lightly pigmented irides.

Non-Clinical Toxicology
Should not be used when untreated narrow-angle glaucoma, or untreated anatomically narrow angles are present, or if the patient is hypersensitive to any component of this preparation.

FOR TOPICAL OPHTHALMIC USE ONLYNOT FOR INJECTION. This preparation may cause CNS disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate. To minimize absorption, use only 1 drop of 0.5% CYCLOGYL solution per eye, followed by pressure applied over the nasolacrimal sac for two to three minutes. Observe infants closely for at least 30 minutes following instillation.

Mydriatics may produce a transient elevation of intraocular pressure.

Cyclopentolate may interfere with the ocular anti-hypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.

The lacrimal sac should be compressed by digital pressure for two to three minutes after instillation to reduce excessive systemic absorption. Caution should be observed when considering use of this medication in the presence of Down's syndrome and in those predisposed to angle-closure glaucoma.

Ocular:

Non-ocular:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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