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Cyclopentolate Hydrochloride

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Overview

What is Cyclopentolate Hydrochloride?

Cyclopentolate Hydrochloride Ophthalmic Solution is an anticholinergic prepared as a sterile, borate buffered solution for topical ocular use. It is supplied in two strengths.

Chemical name:

2-(Dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate hydrochloride

MW=327.85         CHNO ⋅ HCl

The active ingredient is represented by the structural formula:

Cyclopentolate Hydrochloride Ophthalmic Solution USP, 1% & 2%

Each mL contains: Active:

Inactives:

Preservative:



What does Cyclopentolate Hydrochloride look like?



What are the available doses of Cyclopentolate Hydrochloride?

Sorry No records found.

What should I talk to my health care provider before I take Cyclopentolate Hydrochloride?

Sorry No records found

How should I use Cyclopentolate Hydrochloride?

Cyclopentolate hydrochloride ophthalmic solution is used to produce mydriasis and cycloplegia.


What interacts with Cyclopentolate Hydrochloride?

Sorry No Records found


What are the warnings of Cyclopentolate Hydrochloride?

Sorry No Records found


What are the precautions of Cyclopentolate Hydrochloride?

Sorry No Records found


What are the side effects of Cyclopentolate Hydrochloride?

Sorry No records found


What should I look out for while using Cyclopentolate Hydrochloride?

Cyclopentolate Hydrochloride Ophthalmic Solution should not be used when untreated narrow-angle glaucoma, or untreated anatomically narrow angles are present, or if the patient is hypersensitive to any component of this preparation.

For topical ophthalmic use only. Not for injection. This preparation may cause CNS disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate. To minimize absorption, use only 1 drop of 0.5% cyclopentolate hydrochloride ophthalmic solution per eye, followed by pressure applied over the nasolacrimal sac for two to three minutes. Observe infants closely for at least 30 minutes.

Mydriatics may produce a transient elevation of intraocular pressure.


What might happen if I take too much Cyclopentolate Hydrochloride?

Excessive dosage may produce behavioral disturbances, tachycardia, hyperpyrexia, hypertension, elevated intraocular pressure, vasodilation, urinary retention, diminished gastrointestinal motility and decreased secretion in salivary and sweat glands, pharynx, bronchi and nasal passages. Patients exhibiting signs of overdosage should receive supportive care and monitoring.


How should I store and handle Cyclopentolate Hydrochloride?

Store in a refrigerator at 2ºC to 8ºC (36ºF to 46ºF).Do not freeze or shake. Protect from light. This product contains no preservative.Store in a refrigerator at 2ºC to 8ºC (36ºF to 46ºF).Do not freeze or shake. Protect from light. This product contains no preservative.Cyclopentolate Hydrochloride Ophthalmic Solution, USP is a sterile ophthalmic solution supplied in white opaque plastic dropper bottles as follows: Cyclopentolate Hydrochloride Ophthalmic Solution USP, 1%  2 mL NDC 17478-100-02  5 mL NDC 17478-100-1015 mL NDC 17478-100-12 Cyclopentolate Hydrochloride Ophthalmic Solution USP, 2%  2 mL NDC 17478-097-02  5 mL NDC 17478-097-1015 mL NDC 17478-097-12 DO NOT USE IF IMPRINTED SEAL IS BROKEN OR MISSING.Cyclopentolate Hydrochloride Ophthalmic Solution, USP is a sterile ophthalmic solution supplied in white opaque plastic dropper bottles as follows: Cyclopentolate Hydrochloride Ophthalmic Solution USP, 1%  2 mL NDC 17478-100-02  5 mL NDC 17478-100-1015 mL NDC 17478-100-12 Cyclopentolate Hydrochloride Ophthalmic Solution USP, 2%  2 mL NDC 17478-097-02  5 mL NDC 17478-097-1015 mL NDC 17478-097-12 DO NOT USE IF IMPRINTED SEAL IS BROKEN OR MISSING.Cyclopentolate Hydrochloride Ophthalmic Solution, USP is a sterile ophthalmic solution supplied in white opaque plastic dropper bottles as follows: Cyclopentolate Hydrochloride Ophthalmic Solution USP, 1%  2 mL NDC 17478-100-02  5 mL NDC 17478-100-1015 mL NDC 17478-100-12 Cyclopentolate Hydrochloride Ophthalmic Solution USP, 2%  2 mL NDC 17478-097-02  5 mL NDC 17478-097-1015 mL NDC 17478-097-12 DO NOT USE IF IMPRINTED SEAL IS BROKEN OR MISSING.Cyclopentolate Hydrochloride Ophthalmic Solution, USP is a sterile ophthalmic solution supplied in white opaque plastic dropper bottles as follows: Cyclopentolate Hydrochloride Ophthalmic Solution USP, 1%  2 mL NDC 17478-100-02  5 mL NDC 17478-100-1015 mL NDC 17478-100-12 Cyclopentolate Hydrochloride Ophthalmic Solution USP, 2%  2 mL NDC 17478-097-02  5 mL NDC 17478-097-1015 mL NDC 17478-097-12 DO NOT USE IF IMPRINTED SEAL IS BROKEN OR MISSING.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

This anticholinergic preparation blocks the responses of the sphincter muscle of the iris and the accommodative muscle of the ciliary body to cholinergic stimulation, producing pupillary dilation (mydriasis) and paralysis of accommodation (cycloplegia). It acts rapidly, but has a shorter duration than atropine. Maximal cycloplegia occurs within 25 to 75 minutes after instillation. Complete recovery of accommodation usually takes 6 to 24 hours. Complete recovery from mydriasis in some individuals may require several days. Heavily pigmented irides may require more doses than lightly pigmented irides.

Non-Clinical Toxicology
Cyclopentolate Hydrochloride Ophthalmic Solution should not be used when untreated narrow-angle glaucoma, or untreated anatomically narrow angles are present, or if the patient is hypersensitive to any component of this preparation.

For topical ophthalmic use only. Not for injection. This preparation may cause CNS disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate. To minimize absorption, use only 1 drop of 0.5% cyclopentolate hydrochloride ophthalmic solution per eye, followed by pressure applied over the nasolacrimal sac for two to three minutes. Observe infants closely for at least 30 minutes.

Mydriatics may produce a transient elevation of intraocular pressure.

Drug Interactions:

General:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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