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Cystografin Dilute
Overview
What is Cystografin Dilute?
Cystografin Dilute (Diatrizoate
Meglumine Injection USP 18%) is a radiopaque contrast agent supplied
as a sterile, aqueous solution. Each mL provides 180 mg diatrizoate
meglumine with 0.4 mg edetate disodium as a sequestering agent. Each
mL of solution also contains approximately 85 mg organically bound
iodine. At the time of manufacture, the air in the container is replaced
by nitrogen.
What does Cystografin Dilute look like?
What are the available doses of Cystografin Dilute?
Sorry No records found.
What should I talk to my health care provider before I take Cystografin Dilute?
Sorry No records found
How should I use Cystografin Dilute?
Cystografin Dilute is indicated
for retrograde cystourethrography.
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Preparation of the patient:
What interacts with Cystografin Dilute?
This preparation is contraindicated in patients with a hypersensitivity to salts of diatrizoic acid.
What are the warnings of Cystografin Dilute?
A
history of sensitivity to iodine or to other
contrast agents is not an absolute contraindication to the use of
diatrizoate meglumine, but calls for extreme caution in administration.
Severe sensitivity reactions are
more likely to occur in patients with a personaI or family history
of bronchial asthma, significant allergies, or previous reactions
to contrast agents.
A
history of sensitivity to iodine or to other
contrast agents is not an absolute contraindication to the use of
diatrizoate meglumine, but calls for extreme caution in administration.
What are the precautions of Cystografin Dilute?
Safe and effective use of this
preparation depends upon proper dosage, correct technique, adequate
precautions, and readiness for emergencies.
Retrograde cystourethrography should be performed
with caution in patients with a known active infectious process of
the urinary tract.
Sterile
technique should be employed in administration. During administration,
care should be taken to avoid excessive pressure, rapid or acute distention
of the bladder, and trauma.
Contrast agents may interfere with some chemical determinations made
on urine specimens; therefore, urine should be collected before administration
of the contrast medium or two or more days afterwards.
Pregnancy–Teratogenic Effects:
Pregnancy Category C
Animal reproduction studies have
not been conducted with diatrizoate meglumine injection. It is also
not known whether diatrizoate meglumine injection can cause fetal
harm when administered to a pregnant woman or can affect reproduction
capacity. Cystografin Dilute should be administered to a pregnant
woman only if clearly needed.
What are the side effects of Cystografin Dilute?
Retrograde genitourinary procedures
may cause such complications as hematuria, perforation of the urethra
or bladder, introduction of infection into the genitourinary tract,
and oliguria or anuria.
If intravasation of this drug occurs, the reactions which may be
associated with intravenous administration may possibly be encountered.
Hypersensitivity or anaphylactoid reactions may occur. Severe reactions
may be manifested by edema of the face and glottis, respiratory distress,
convulsions or shock; such reactions may prove fatal unless promptly
controlled by such emergency measures as maintenance of a clear airway
and immediate use of oxygen and resuscitative drugs.
Endocrine:
What should I look out for while using Cystografin Dilute?
This preparation is contraindicated
in patients with a hypersensitivity to salts of diatrizoic acid.
Severe sensitivity reactions are
more likely to occur in patients with a personaI or family history
of bronchial asthma, significant allergies, or previous reactions
to contrast agents.
A
history of sensitivity to iodine or to other
contrast agents is not an absolute contraindication to the use of
diatrizoate meglumine, but calls for extreme caution in administration.
What might happen if I take too much Cystografin Dilute?
Sorry No Records found
How should I store and handle Cystografin Dilute?
Store at 20-25°C (68-77°F) [See USP]. Protect from light.Cystografin Dilute (Diatrizoate Meglumine Injection USP 18%) is available in packages of ten 300 mL bottIes (NDC 0270-1410-30).
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
Non-Clinical Toxicology
This preparation is contraindicated in patients with a hypersensitivity to salts of diatrizoic acid.Severe sensitivity reactions are more likely to occur in patients with a personaI or family history of bronchial asthma, significant allergies, or previous reactions to contrast agents.
A history of sensitivity to iodine or to other contrast agents is not an absolute contraindication to the use of diatrizoate meglumine, but calls for extreme caution in administration.
Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibiotics or potent diuretics such as furosemide. Renal function should be carefully monitored, especially if higher dosages of the aminoglycosides are to be administered or if therapy is prolonged, because of the potential nephrotoxicity and ototoxicity of aminoglycoside antibiotics. Nephrotoxicity and ototoxicity were not noted when ceftazidime was given alone in clinical trials.
Chloramphenicol has been shown to be antagonistic to beta-lactam antibiotics, including ceftazidime, based on studies and time kill curves with enteric gram-negative bacilli. Due to the possibility of antagonism , particularly when bactericidal activity is desired, this drug combination should be avoided.
In common with other antibiotics, ceftazidime may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Safe and effective use of this preparation depends upon proper dosage, correct technique, adequate precautions, and readiness for emergencies.
Retrograde cystourethrography should be performed with caution in patients with a known active infectious process of the urinary tract.
Sterile technique should be employed in administration. During administration, care should be taken to avoid excessive pressure, rapid or acute distention of the bladder, and trauma.
Contrast agents may interfere with some chemical determinations made on urine specimens; therefore, urine should be collected before administration of the contrast medium or two or more days afterwards.
Retrograde genitourinary procedures may cause such complications as hematuria, perforation of the urethra or bladder, introduction of infection into the genitourinary tract, and oliguria or anuria.
If intravasation of this drug occurs, the reactions which may be associated with intravenous administration may possibly be encountered. Hypersensitivity or anaphylactoid reactions may occur. Severe reactions may be manifested by edema of the face and glottis, respiratory distress, convulsions or shock; such reactions may prove fatal unless promptly controlled by such emergency measures as maintenance of a clear airway and immediate use of oxygen and resuscitative drugs.
Endocrine:
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
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Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72Tips
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Interactions
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