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Folic Acid, Vitamin D3

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Overview

What is DermacinRx PureFolix?

PureFolix™ is an orally administered prescription folate product for the dietary management of patients with unique nutritional needs requiring increased folate levels and Vitamin D supplementation due to Vitamin D deficiency.

PureFolix should be administered under the supervision of a licensed medical practitioner.

Each tablet contains: Folic Acid ..........................................................................1 mg Vitamin D (cholecalciferol) ......................................5000 IU



What does DermacinRx PureFolix look like?



What are the available doses of DermacinRx PureFolix?

Sorry No records found.

What should I talk to my health care provider before I take DermacinRx PureFolix?

Sorry No records found

How should I use DermacinRx PureFolix?

PureFolix is indicated for dietary management of patients with unique nutritional needs requiring increased folate levels and Vitamin D supplementation.

PureFolix can be taken by women of childbearing age, pregnant women, and lactating and nonlactating mothers.

Take one tablet daily or as directed by a healthcare practitioner.


What interacts with DermacinRx PureFolix?

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. PureFolix is contraindicated in patients with hypercalcemia, malabsorption syndrome, abnormal sensitivity to the toxic effects of vitamin D, and hypervitaminosis D.



What are the warnings of DermacinRx PureFolix?

Sorry No Records found


What are the precautions of DermacinRx PureFolix?

Sorry No Records found


What are the side effects of DermacinRx PureFolix?

Sorry No records found


What should I look out for while using DermacinRx PureFolix?

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. PureFolix is contraindicated in patients with hypercalcemia, malabsorption syndrome, abnormal sensitivity to the toxic effects of vitamin D, and hypervitaminosis D.


What might happen if I take too much DermacinRx PureFolix?

Sorry No Records found


How should I store and handle DermacinRx PureFolix?

Store the generator and the eluate, Sodium Pertechnetate Tc99m Injection, below 25°C (77°F). Do not freeze.Store the saline eluent vial below 25°C (77°F). Do not freeze.Storage should be in accordance with local regulations for radioactive materials.Store the generator and the eluate, Sodium Pertechnetate Tc99m Injection, below 25°C (77°F). Do not freeze.Store the saline eluent vial below 25°C (77°F). Do not freeze.Storage should be in accordance with local regulations for radioactive materials.Store the generator and the eluate, Sodium Pertechnetate Tc99m Injection, below 25°C (77°F). Do not freeze.Store the saline eluent vial below 25°C (77°F). Do not freeze.Storage should be in accordance with local regulations for radioactive materials.PureFolix Tablets are supplied as round, light yellow tablets printed with one side scored, the other side plain and dispensed in child-resistant bottles of 30 tablets (NDC 59088-090-54*).* This product is a prescription-folate with or without other dietary ingredients that – due to increased folate levels (AUG 2 1973 FR 20750), requires an Rx on the label because of increased risk associated with masking of B12 deficiency (pernicious anemia). Based on our assessment of the risk of obscuring pernicious anemia, this product requires licensed medical supervision, an Rx status, and a National Drug Code (NDC) or similarly-formatted product code, as required by pedigree reporting requirements and supply-chain control as well as in some cases, for insurance-reimbursement applications. All prescriptions using this product shall be pursuant to state statutes as applicable. This is not an Orange Book product. This product may be administered only under a physician’s supervision. There are no implied or explicit claims on therapeutic equivalencePureFolix Tablets are supplied as round, light yellow tablets printed with one side scored, the other side plain and dispensed in child-resistant bottles of 30 tablets (NDC 59088-090-54*).* This product is a prescription-folate with or without other dietary ingredients that – due to increased folate levels (AUG 2 1973 FR 20750), requires an Rx on the label because of increased risk associated with masking of B12 deficiency (pernicious anemia). Based on our assessment of the risk of obscuring pernicious anemia, this product requires licensed medical supervision, an Rx status, and a National Drug Code (NDC) or similarly-formatted product code, as required by pedigree reporting requirements and supply-chain control as well as in some cases, for insurance-reimbursement applications. All prescriptions using this product shall be pursuant to state statutes as applicable. This is not an Orange Book product. This product may be administered only under a physician’s supervision. There are no implied or explicit claims on therapeutic equivalencePureFolix Tablets are supplied as round, light yellow tablets printed with one side scored, the other side plain and dispensed in child-resistant bottles of 30 tablets (NDC 59088-090-54*).* This product is a prescription-folate with or without other dietary ingredients that – due to increased folate levels (AUG 2 1973 FR 20750), requires an Rx on the label because of increased risk associated with masking of B12 deficiency (pernicious anemia). Based on our assessment of the risk of obscuring pernicious anemia, this product requires licensed medical supervision, an Rx status, and a National Drug Code (NDC) or similarly-formatted product code, as required by pedigree reporting requirements and supply-chain control as well as in some cases, for insurance-reimbursement applications. All prescriptions using this product shall be pursuant to state statutes as applicable. This is not an Orange Book product. This product may be administered only under a physician’s supervision. There are no implied or explicit claims on therapeutic equivalence


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Clinical Information

Chemical Structure

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Clinical Pharmacology

The synthesis of the major biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of ergocalciferol takes place in the liver (to 25-hydroxyvitamin D) and the second in the kidneys (to 1,25-dihydroxyvitamin D). Vitamin D metabolites promote the active absorption of calcium and phosphorus by the small intestine, thus elevating serum calcium and phosphate levels sufficiently to permit bone mineralization. Vitamin D metabolites also mobilize calcium and phosphate from bone and probably increase the reabsorption of calcium and perhaps also of phosphate by the renal tubules.

There is a time lag of 10 to 24 hours between the administration of vitamin D and the initiation of its action in the body due to the necessity of synthesis of the active metabolites in the liver and kidneys. Parathyroid hormone is responsible for the regulation of this metabolism in the kidneys.

Non-Clinical Toxicology
This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. PureFolix is contraindicated in patients with hypercalcemia, malabsorption syndrome, abnormal sensitivity to the toxic effects of vitamin D, and hypervitaminosis D.

Potassium-sparing diuretics, angiotensin-converting enzyme inhibitors (see ).

KEEP OUT OF THE REACH OF CHILDREN.

Tell your doctor if you have: kidney problems, thyroid disease. This medication should be used as directed during pregnancy or while breast-feeding. Consult your doctor about the risks and benefits.

Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient. Folic acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations progress.

Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

You should call your doctor for medical advice about serious adverse events. To report adverse side effects or to obtain product information, contact PureTek Corporation, at 1-877-921-7873.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

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Tips

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Interactions

Interactions

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