Disclaimer:

Medidex is not a provider of medical services and all information is provided for the convenience of the user. No medical decisions should be made based on the information provided on this website without first consulting a licensed healthcare provider.This website is intended for persons 18 years or older. No person under 18 should consult this website without the permission of a parent or guardian.

Dermasorb HC Complete Kit

×

Overview

What is Dermasorb HC Complete Kit?

The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Hydrocortisone is a member of this class. Chemically hydrocortisone is pregn-4-ene-3, 20-dione, 11, 17, 21-trihydroxy, (11ß). Its structural formula is:

Each mL of DERMASORB™HC (Hydrocortisone USP, 2%) Lotion contains 20 mg hydrocortisone USP in a lotion base consisting of water, isopropyl alcohol, polysorbate 20, propylene glycol, and benzalkonium chloride.



What does Dermasorb HC Complete Kit look like?



What are the available doses of Dermasorb HC Complete Kit?

Sorry No records found.

What should I talk to my health care provider before I take Dermasorb HC Complete Kit?

Sorry No records found

How should I use Dermasorb HC Complete Kit?

DERMASORB™HC lotion is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Topical corticosteroids are generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition.

Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.


What interacts with Dermasorb HC Complete Kit?

DERMASORB™HC lotion is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.



What are the warnings of Dermasorb HC Complete Kit?

Sorry No Records found


What are the precautions of Dermasorb HC Complete Kit?

General

Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients. Conditions that augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.

Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.

Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity (See ).

If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted.

In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.


What are the side effects of Dermasorb HC Complete Kit?

The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning, Itching, Irritation, Dryness, Folliculitis, Hypertrichosis, Acneiform eruptions, Hypopigmentation, Perioral dermatitis, Allergic contact dermatitis, Maceration of the skin, Secondary infection, Skin Atrophy, Striae, and Miliaria.


What should I look out for while using Dermasorb HC Complete Kit?

DERMASORB™HC lotion is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.


What might happen if I take too much Dermasorb HC Complete Kit?

Topically applied corticosteroids can be absorbed in sufficient amounts to produce systems effects (See ).


How should I store and handle Dermasorb HC Complete Kit?

ZOSYN (piperacillin and tazobactam for injection, USP) pharmacy bulk vials should be stored at controlled room temperature 20°C to 25°C (68°F to 77°F) prior to reconstitution.DERMASORB™ HC (Hydrocortisone USP, 2%) Lotion is supplied in:1 fluid ounce (29.6 ml) bottle NDC 0316-0201-01Rx OnlyPRINTED IN USAP6171.01Manufactured and Distributed by: Crown Laboratories, Inc., Johnson City, TN, 37604DERMASORB™ HC (Hydrocortisone USP, 2%) Lotion is supplied in:1 fluid ounce (29.6 ml) bottle NDC 0316-0201-01Rx OnlyPRINTED IN USAP6171.01Manufactured and Distributed by: Crown Laboratories, Inc., Johnson City, TN, 37604DERMASORB™ HC (Hydrocortisone USP, 2%) Lotion is supplied in:1 fluid ounce (29.6 ml) bottle NDC 0316-0201-01Rx OnlyPRINTED IN USAP6171.01Manufactured and Distributed by: Crown Laboratories, Inc., Johnson City, TN, 37604DERMASORB™ HC (Hydrocortisone USP, 2%) Lotion is supplied in:1 fluid ounce (29.6 ml) bottle NDC 0316-0201-01Rx OnlyPRINTED IN USAP6171.01Manufactured and Distributed by: Crown Laboratories, Inc., Johnson City, TN, 37604DERMASORB™ HC (Hydrocortisone USP, 2%) Lotion is supplied in:1 fluid ounce (29.6 ml) bottle NDC 0316-0201-01Rx OnlyPRINTED IN USAP6171.01Manufactured and Distributed by: Crown Laboratories, Inc., Johnson City, TN, 37604DERMASORB™ HC (Hydrocortisone USP, 2%) Lotion is supplied in:1 fluid ounce (29.6 ml) bottle NDC 0316-0201-01Rx OnlyPRINTED IN USAP6171.01Manufactured and Distributed by: Crown Laboratories, Inc., Johnson City, TN, 37604


×

Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions.

The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.

Non-Clinical Toxicology
DERMASORB™HC lotion is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

General

Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients. Conditions that augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.

Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.

Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity (See ).

If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted.

In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.

The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning, Itching, Irritation, Dryness, Folliculitis, Hypertrichosis, Acneiform eruptions, Hypopigmentation, Perioral dermatitis, Allergic contact dermatitis, Maceration of the skin, Secondary infection, Skin Atrophy, Striae, and Miliaria.

×

Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

×

Review

Rate this treatment and share your opinion


Helpful tips to write a good review:

  1. Only share your first hand experience as a consumer or a care giver.
  2. Describe your experience in the Comments area including the benefits, side effects and how it has worked for you. Do not provide personal information like email addresses or telephone numbers.
  3. Fill in the optional information to help other users benefit from your review.

Reason for Taking This Treatment

(required)

Click the stars to rate this treatment

This medication has worked for me.




This medication has been easy for me to use.




Overall, I have been satisfied with my experience.




Write a brief description of your experience with this treatment:

2000 characters remaining

Optional Information

Help others benefit from your review by filling in the information below.
I am a:
Gender:
×

Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
×

Tips

Tips

×

Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).