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Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate

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Overview

What is Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

A single-entity amphetamine product combining the neutral sulfate salts of dextroamphetamine and amphetamine, with the dextro isomer of amphetamine saccharate and d,l-amphetamine aspartate monohydrate.

In addition, each tablet for oral administration contains the following inactive ingredients: crospovidone, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch. The 5 mg, 7.5 mg and 10 mg tablets contain D&C Yellow #10 Aluminum Lake and FD&C Blue #1 Aluminum Lake. The 12.5 mg, 15 mg, 20 mg, and 30 mg tablets contain D&C Yellow #10 Aluminum Lake.



What does Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate look like?



What are the available doses of Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Sorry No records found.

What should I talk to my health care provider before I take Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Sorry No records found

How should I use Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets are indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and Narcolepsy.

Regardless of indication, amphetamines should be administered at the lowest effective dosage and dosage should be individually adjusted according to the therapeutic needs and response of the patient. Late evening doses should be avoided because of the resulting insomnia.


What interacts with Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma.


Agitated states.


Patients with a history of drug abuse.


During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result).



What are the warnings of Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Serious Cardiovascular Events

Stimulant medications cause a modest increase in average blood pressure (about 2-4 mmHg) and average heart rate (about 3-6 bpm) [see ], and individuals may have larger increases. While the mean changes alone would not be expected to have short-term consequences, all patients should be monitored for larger changes in heart rate and blood pressure. Caution is indicated in treating patients whose underlying medical conditions might be compromised by increases in blood pressure or heart rate, e.g., those with pre-existing hypertension, heart failure, recent myocardial infarction, or ventricular arrhythmia (see ).

Children, adolescents, or adults who are being considered for treatment with stimulant medications should have a careful history (including assessment for a family history of sudden death or ventricular arrhythmia) and physical exam to assess for the presence of cardiac disease, and should receive further cardiac evaluation if findings suggest such disease (e.g. electrocardiogram and echocardiogram). Patients who develop symptoms such as exertional chest pain, unexplained syncope, or other symptoms suggestive of cardiac disease during stimulant treatment should undergo a prompt cardiac evaluation.

Psychiatric Adverse Events

Administration of stimulants may exacerbate symptoms of behavior disturbance and thought disorder in patients with pre-existing psychotic disorder.

Particular care should be taken in using stimulants to treat ADHD patients with comorbid bipolar disorder because of concern for possible induction of mixed/manic episode in such patients. Prior to initiating treatment with a stimulant, patients with comorbid depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder; such screening should include a detailed psychiatric history, including a family history of suicide, bipolar disorder, and depression.

Treatment emergent psychotic or manic symptoms, e.g., hallucinations, delusional thinking, or mania in children and adolescents without prior history of psychotic illness or mania can be caused by stimulants at usual doses. If such symptoms occur, consideration should be given to a possible causal role of the stimulant, and discontinuation of treatment may be appropriate. In a pooled analysis of multiple short-term, placebo-controlled studies, such symptoms occurred in about 0.1% (4 patients with events out of 3482 exposed to methylphenidate or amphetamine for several weeks at usual doses) of stimulant-treated patients compared to 0 in placebo-treated patients.

Aggressive behavior or hostility is often observed in children and adolescents with ADHD, and has been reported in clinical trials and the postmarketing experience of some medications indicated for the treatment of ADHD. Although there is no systematic evidence that stimulants cause aggressive behavior or hostility, patients beginning treatment for ADHD should be monitored for the appearance of or worsening of aggressive behavior or hostility.

Long-Term Suppression of Growth

Careful follow-up of weight and height in children ages 7 to 10 years who were randomized to either methylphenidate or non-medication treatment groups over 14 months, as well as in naturalistic subgroups of newly methylphenidate-treated and non-medication treated children over 36 months (to the ages of 10 to 13 years), suggests that consistently medicated children (i.e., treatment for 7 days per week throughout the year) have a temporary slowing in growth rate (on average, a total of about 2 cm less growth in height and 2.7 kg less growth in weight over 3 years), without evidence of growth rebound during this period of development. Published data are inadequate to determine whether chronic use of amphetamines may cause a similar suppression of growth, however, it is anticipated that they will likely have this effect as well. Therefore, growth should be monitored during treatment with stimulants, and patients who are not growing or gaining weight as expected may need to have their treatment interrupted.

Seizures

There is some clinical evidence that stimulants may lower the convulsive threshold in patients with prior history of seizure, in patients with prior EEG abnormalities in absence of seizures, and very rarely, in patients without a history of seizures and no prior EEG evidence of seizures. In the presence of seizures, the drug should be discontinued.

Visual Disturbance

Difficulties with accommodation and blurring of vision have been reported with stimulant treatment.


What are the precautions of Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

General

The least amount of amphetamine feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate should be used with caution in patients who use other sympathomimetic drugs.

Tics

Amphetamines have been reported to exacerbate motor and phonic tics and Tourette's syndrome. Therefore, clinical evaluation for tics and Tourette's syndrome in children and their families should precede use of stimulant medications.

Information for Patients

Amphetamines may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or vehicles; the patient should therefore be cautioned accordingly.

Drug Interactions

Acidifying agents

Urinary acidifying agents

Adrenergic blocker

Alkalinizing agents

Antidepressants, tricyclic

MAO inhibitors

Antihistamines

Antihypertensives

Chlorpromazine

Ethosuximide

Haloperidol

Lithium carbonate

Meperidine

Methenamine therapy

Norepinephrine

Phenobarbital

Phenytoin

Propoxyphene

Veratrum alkaloids

Drug/Laboratory Test Interactions

Amphetamines can cause a significant elevation in plasma corticosteroid levels. This increase is greatest in the evening. Amphetamines may interfere with urinary steroid determinations.

Carcinogenesis/Mutagenesis and Impairment of Fertility

No evidence of carcinogenicity was found in studies in which d,l-amphetamine (enantiomer ratio of 1:1) was administered to mice and rats in the diet for 2 years at doses of up to 30 mg/kg/day in male mice, 19 mg/kg/day in female mice, and 5 mg/kg/day in male and female rats. These doses are approximately 2.4, 1.5, and 0.8 times, respectively, the maximum recommended human dose of 30 mg/day [child] on a mg/m body surface area basis.

Amphetamine, in the enantiomer ratio present in dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate (immediate-release)(d- to l- ratio of 3:1), was not clastogenic in the mouse bone marrow micronucleus test and was negative when tested in the E. coli component of the Ames test . d,l-Amphetamine (1:1 enantiomer ratio) has been reported to produce a positive response in the mouse bone marrow micronucleus test, an equivocal response in the Ames test, and negative responses in the sister chromatid exchange and chromosomal aberration assays.

Amphetamine, in the enantiomer ratio present in dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate (immediate-release)(d- to l- ratio of 3:1), did not adversely affect fertility or early embryonic development in the rat at doses of up to 20 mg/kg/day (approximately 5 times the maximum recommended human dose of 30 mg/day on a mg/m body surface area basis).

Pregnancy

Teratogenic Effects

Amphetamine, in the enantiomer ratio present in dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate (d- to l- ratio of 3:1), had no apparent effects on embryofetal morphological development or survival when orally administered to pregnant rats and rabbits throughout the period of organogenesis at doses of up to 6 and 16 mg/kg/day, respectively. These doses are approximately 1.5 and 8 times, respectively, the maximum recommended human dose of 30 mg/day [child] on a mg/m body surface area basis. Fetal malformations and death have been reported in mice following parenteral administration of d-amphetamine doses of 50 mg/kg/day (approximately 6 times that of a human dose of 30 mg/day [child] on a mg/m basis) or greater to pregnant animals. Administration of these doses was also associated with severe maternal toxicity.

A number of studies in rodents indicate that prenatal or early postnatal exposure to amphetamine (d- or d,l-), at doses similar to those used clinically, can result in long-term neurochemical and behavioral alterations. Reported behavioral effects include learning and memory deficits, altered locomotor activity, and changes in sexual function.

There are no adequate and well-controlled studies in pregnant women. There has been one report of severe congenital bony deformity, tracheo-esophageal fistula, and anal atresia (vater association) in a baby born to a woman who took dextroamphetamine sulfate with lovastatin during the first trimester of pregnancy. Amphetamines should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Nonteratogenic Effects

Infants born to mothers dependent on amphetamines have an increased risk of premature delivery and low birth weight. Also, these infants may experience symptoms of withdrawal as demonstrated by dysphoria, including agitation, and significant lassitude.

Usage in Nursing Mothers

Amphetamines are excreted in human milk. Mothers taking amphetamines should be advised to refrain from nursing.

Pediatric Use

Long-term effects of amphetamines in children have not been well established. Amphetamines are not recommended for use in children under 3 years of age with Attention Deficit Hyperactivity Disorder described under .

Geriatric Use

Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate has not been studied in the geriatric population.


What are the side effects of Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Cardiovascular:

Central Nervous System:

Gastrointestinal:

Allergic:

Endocrine:


What should I look out for while using Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma.

Agitated states.

Patients with a history of drug abuse.

During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result).


What might happen if I take too much Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Individual patient response to amphetamines varies widely. Toxic symptoms may occur idiosyncratically at low doses.


How should I store and handle Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate?

Store below 30°C (86°F).Manufactured by:DANBURY PHARMACAL, INC.Danbury, CT 06810Store below 30°C (86°F).Manufactured by:DANBURY PHARMACAL, INC.Danbury, CT 06810Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 5 mg, round, green, double-scored, debossed MP 441 on one side; the other side plainBottles of 100            NDC 53489-564-01Bottles of 250            NDC 53489-564-03Bottles of 500            NDC 53489-564-05Bottles of 1000          NDC 53489-564-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 7.5 mg, oval, green, double-scored, debossed MP 442 on one side; the other side plainBottles of 100            NDC 53489-565-01Bottles of 250            NDC 53489-565-03Bottles of 500            NDC 53489-565-05Bottles of 1000          NDC 53489-565-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 10 mg, round, green, double-scored, debossed MP 443 on one side; the other side plainBottles of 100            NDC 53489-566-01Bottles of 250            NDC 53489-566-03Bottles of 500            NDC 53489-566-05Bottles of 1000          NDC 53489-566-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 12.5 mg, round, yellow, double-scored, debossed MP 444 on one side; the other side plainBottles of 100            NDC 53489-567-01Bottles of 250            NDC 53489-567-03Bottles of 500            NDC 53489-567-05Bottles of 1000          NDC 53489-567-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 15 mg, oval, yellow, double-scored, debossed MP 445 on one side; the other side plainBottles of 100            NDC 53489-568-01Bottles of 250            NDC 53489-568-03Bottles of 500            NDC 53489-568-05Bottles of 1000          NDC 53489-568-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 20 mg, round, yellow, double-scored, debossed MP 446 on one side; the other side plainBottles of 100            NDC 53489-569-01Bottles of 250            NDC 53489-569-03Bottles of 500            NDC 53489-569-05Bottles of 1000          NDC 53489-569-10Dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets 30 mg, round, yellow, double-scored, debossed MP 447 on one side; the other side plainBottles of 100            NDC 53489-570-01Bottles of 250            NDC 53489-570-03Bottles of 500            NDC 53489-570-05Bottles of 1000          NDC 53489-570-10


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. The mode of therapeutic action in Attention Deficit Hyperactivity Disorder (ADHD) is not known. Amphetamines are thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space.

Non-Clinical Toxicology
Advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma.

Agitated states.

Patients with a history of drug abuse.

During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result).

Acidifying agents

Urinary acidifying agents

Adrenergic blocker

Alkalinizing agents

Antidepressants, tricyclic

MAO inhibitors

Antihistamines

Antihypertensives

Chlorpromazine

Ethosuximide

Haloperidol

Lithium carbonate

Meperidine

Methenamine therapy

Norepinephrine

Phenobarbital

Phenytoin

Propoxyphene

Veratrum alkaloids

Array

Cardiovascular:

Central Nervous System:

Gastrointestinal:

Allergic:

Endocrine:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Review

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).