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DuoDote

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Overview

What is DuoDote?

Each prefilled DuoDote autoinjector provides a single intramuscular dose of atropine, a cholinergic muscarinic antagonist, and pralidoxime chloride, a cholinesterase reactivator, in a self-contained unit, specifically designed for administration by emergency medical services personnel.

When activated, each DuoDote autoinjector delivers the following:

Atropine occurs as white crystals, usually needle-like, or as a white, crystalline powder. It is slightly soluble in water with a molecular weight of 289.38. Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and l-hyoscyamine, with activity due almost entirely to the levo isomer of the drug.

Chemically, atropine is designated as 1αH,5αH-Tropan-3α-ol (±)-tropate. Its empirical formula is CHNO and its structural formula is as follows:

Pralidoxime chloride is an odorless, white to pale-yellow crystalline powder, freely soluble in water, with a molecular weight of 172.61. Chemically, pralidoxime chloride is designated as 2-formyl-l-methylpyridinium chloride oxime. Its empirical formula is CHClNO and its structural formula is indicated above.



What does DuoDote look like?



What are the available doses of DuoDote?

Each single-dose DuoDote autoinjector contains atropine (2.1 mg/0.7 mL) plus pralidoxime chloride (600 mg/2 mL). ()

What should I talk to my health care provider before I take DuoDote?

How should I use DuoDote?

 


What interacts with DuoDote?

Sorry No Records found


What are the warnings of DuoDote?

Sorry No Records found


What are the precautions of DuoDote?

Sorry No Records found


What are the side effects of DuoDote?

Sorry No records found


What should I look out for while using DuoDote?

None.


What might happen if I take too much DuoDote?


How should I store and handle DuoDote?

Each single-dose DuoDote (atropine and pralidoxime chloride) autoinjector contains atropine (2.1 mg/0.7 mL; colorless to yellow solution, visible in front chamber) and pralidoxime chloride (600 mg/2 mL; colorless to yellow solution, not visible in rear chamber) and is available in a single unit carton, NDC-11704-620-01. Each DuoDote autoinjector is supplied in a pouch that provides protection from light. Each single-dose DuoDote (atropine and pralidoxime chloride) autoinjector contains atropine (2.1 mg/0.7 mL; colorless to yellow solution, visible in front chamber) and pralidoxime chloride (600 mg/2 mL; colorless to yellow solution, not visible in rear chamber) and is available in a single unit carton, NDC-11704-620-01. Each DuoDote autoinjector is supplied in a pouch that provides protection from light.