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E-Z-Paque

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Overview

What is E-Z-Paque?

Liquid E-Z-PAQUE (barium sulfate) is a radiographic contrast agent supplied as a white to lightly colored barium sulfate suspension (60%w/v) for oral administration. The active ingredient barium sulfate is designated chemically as BaSO with a molecular weight of 233.4 g/mol, a density of 4.5 g/cm, and the following chemical structure:

Liquid E-Z-PAQUE contains the following excipients: carboxymethyl cellulose sodium, citric acid, natural and artificial strawberry lemon cream flavor, polysorbate 80, potassium sorbate, purified water, saccharin sodium, simethicone emulsion, sodium benzoate, sodium citrate, sorbitol solution, xanthan gum.



What does E-Z-Paque look like?



What are the available doses of E-Z-Paque?

Liquid E-Z-PAQUE oral suspension: 213 grams of barium sulfate supplied as a suspension (60 % w/v) in a single-dose bottle.

What should I talk to my health care provider before I take E-Z-Paque?

How should I use E-Z-Paque?

Liquid E-Z-PAQUE is indicated for use in single contrast radiographic examinations of the esophagus, stomach, and small bowel to visualize the gastrointestinal (GI) tract in adult and pediatric patients.

The optimal oral dose of Liquid E-Z-PAQUE will vary depending on the size and anatomy of the patient and the procedure being performed. The recommended oral dose of Liquid E-Z-PAQUE:


What interacts with E-Z-Paque?

Sorry No Records found


What are the warnings of E-Z-Paque?

Sorry No Records found


What are the precautions of E-Z-Paque?

Sorry No Records found


What are the side effects of E-Z-Paque?

Sorry No records found


What should I look out for while using E-Z-Paque?

Liquid E-Z-PAQUE is contraindicated in patients with the following conditions:


What might happen if I take too much E-Z-Paque?

Sorry No Records found


How should I store and handle E-Z-Paque?

Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature].Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.A Schedule CII Narcotic.Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature].Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.A Schedule CII Narcotic.Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature].Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.A Schedule CII Narcotic.How SuppliedProvided as: 24 x 355 mL bottles (NDC 32909-186-02).Storage and HandlingHow SuppliedProvided as: 24 x 355 mL bottles (NDC 32909-186-02).Storage and HandlingHow SuppliedProvided as: 24 x 355 mL bottles (NDC 32909-186-02).Storage and Handling


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Due to its high atomic number, barium (the active ingredient in Liquid E-Z-PAQUE) is opaque to x-rays and therefore acts as a positive contrast agent for radiographic studies.

Non-Clinical Toxicology
Liquid E-Z-PAQUE is contraindicated in patients with the following conditions:

Folic acid in large amounts may counteract the antiepileptic effect of phenobarbital, phenytoin and primidone, and increase the frequency of seizures in susceptible children.

Preliminary animal and human studies have shown that small quantities of systemically administered leucovorin enter CSF primarily as 5-methyltetrahydrofolate and, in humans, remain 1 to 3 orders of magnitude lower than usual methotrexate concentrations following intrathecal administration. However, high doses of leucovorin may reduce the efficacy of intrathecally administered methotrexate.

Leucovorin may enhance the toxicity of fluorouracil (see ).

Barium sulfate preparations contain a number of excipients, including natural and artificial flavors and may induce serious hypersensitivity reactions. The manifestations include hypotension, bronchospasm and other respiratory impairments, dermal reactions including rashes, urticaria and itching. A history of bronchial asthma, atopy or a previous reaction to a contrast agent may increase the risk for hypersensitivity reactions. Emergency equipment and trained personnel should be immediately available for treatment of a hypersensitivity reaction.

The following adverse reactions have been identified from spontaneous reporting or clinical studies of barium sulfate administered orally. Because the reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or to establish a causal relationship to drug exposure:

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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