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Evzio
Overview
What is Evzio?
EVZIO (naloxone hydrochloride injection, USP) is a pre-filled, single-use auto-injector. EVZIO is not made with natural rubber latex. Chemically, naloxone hydrochloride is the hydrochloride salt of 17-Allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride with the following structure:
CHNO• HCl
M.W. 363.84
Naloxone hydrochloride occurs as a white to slightly off-white powder, and is soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform.
Each 0.4 mL in EVZIO contains inactive ingredients of 3.34 mg of sodium chloride, hydrochloric acid to adjust pH, and water for injection. The pH range is 3.0 to 4.5.
What does Evzio look like?
What are the available doses of Evzio?
Injection: 0.4 mg/0.4 mL naloxone hydrochloride solution in a pre-filled auto-injector. ()
What should I talk to my health care provider before I take Evzio?
How should I use Evzio?
EVZIO is an opioid antagonist indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression.
EVZIO is intended for immediate administration as emergency therapy in settings where opioids may be present.
EVZIO is not a substitute for emergency medical care.
The should be read by the patient or caregiver at the time they receive a prescription for EVZIO. Provide the following instructions to the patient or caregiver:
Upon actuation, EVZIO automatically inserts the needle intramuscularly or subcutaneously, delivers 0.4 mg naloxone hydrochloride injection, and retracts the needle fully into its housing. Post injection, the black base locks in place, a red indicator appears in the viewing window, and electronic visual and audible instructions signal that EVZIO has delivered the intended dose of naloxone hydrochloride and instructs the user to seek emergency medical attention.
What interacts with Evzio?
Sorry No Records found
What are the warnings of Evzio?
Sorry No Records found
What are the precautions of Evzio?
Sorry No Records found
What are the side effects of Evzio?
Sorry No records found
What should I look out for while using Evzio?
EVZIO is contraindicated in patients known to be hypersensitive to naloxone hydrochloride or to any of the other ingredients.
What might happen if I take too much Evzio?
Sorry No Records found
How should I store and handle Evzio?
Store EVZIO in the outer case provided.Store at controlled room temperature 15°C to 25°C (59°F to 77°F) excursions permitted between 4°C and 40°C (between 39°F and 104°F).Before using, check to make sure the solution in the auto-injector is not discolored. Replace EVZIO if the solution is discolored or contains a precipitate.Store EVZIO in the outer case provided.Store at controlled room temperature 15°C to 25°C (59°F to 77°F) excursions permitted between 4°C and 40°C (between 39°F and 104°F).Before using, check to make sure the solution in the auto-injector is not discolored. Replace EVZIO if the solution is discolored or contains a precipitate.Store EVZIO in the outer case provided.Store at controlled room temperature 15°C to 25°C (59°F to 77°F) excursions permitted between 4°C and 40°C (between 39°F and 104°F).Before using, check to make sure the solution in the auto-injector is not discolored. Replace EVZIO if the solution is discolored or contains a precipitate.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30 NDC 68788-6321-3Bottles of 60 NDC 68788-6321-6Bottles of 90 NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30 NDC 68788-6321-3Bottles of 60 NDC 68788-6321-6Bottles of 90 NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30 NDC 68788-6321-3Bottles of 60 NDC 68788-6321-6Bottles of 90 NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.Rosuvastatin Calcium Tablets, 10 mg Bottles of 30 NDC 68788-6321-3Bottles of 60 NDC 68788-6321-6Bottles of 90 NDC 68788-6321-9 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Protect from moisture.
