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EYLEA

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Overview

What is EYLEA?

EYLEA (aflibercept) is a recombinant fusion protein consisting of portions of human VEGF receptors 1 and 2 extracellular domains fused to the Fc portion of human IgG1 formulated as an iso-osmotic solution for intravitreal administration. Aflibercept is a dimeric glycoprotein with a protein molecular weight of 97 kilodaltons (kDa) and contains glycosylation, constituting an additional 15% of the total molecular mass, resulting in a total molecular weight of 115 kDa. Aflibercept is produced in recombinant Chinese hamster ovary (CHO) cells.

EYLEA is a sterile, clear, and colorless to pale yellow solution. EYLEA is supplied as a preservative-free, sterile, aqueous solution in a single-use, glass vial designed to deliver 0.05 mL (50 microliters) of EYLEA (40 mg/mL in 10 mM sodium phosphate, 40 mM sodium chloride, 0.03% polysorbate 20, and 5% sucrose, pH 6.2).



What does EYLEA look like?



What are the available doses of EYLEA?

40 mg/mL solution for intravitreal injection in a single-use vial ()

What should I talk to my health care provider before I take EYLEA?

How should I use EYLEA?

EYLEA is indicated for the treatment of:

For ophthalmic intravitreal injection. EYLEA must only be administered by a qualified physician.


What interacts with EYLEA?

Sorry No Records found


What are the warnings of EYLEA?

Sorry No Records found


What are the precautions of EYLEA?

Sorry No Records found


What are the side effects of EYLEA?

Sorry No records found


What should I look out for while using EYLEA?

Ocular or periocular infection ()

Active intraocular inflammation ()

Hypersensitivity ()


What might happen if I take too much EYLEA?

Sorry No Records found


How should I store and handle EYLEA?

Each Vial is for single eye use only. EYLEA is supplied in the following presentation [].