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FLUORESCITE

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Overview

What is FLUORESCITE?

FLUORESCITE (fluorescein injection, USP) 10% is supplied as a sterile, unpreserved, unit dose aqueous solution, that has a pH of 8.0 – 9.8 and an osmolality of 572-858 mOsm/kg.

Active ingredient: fluorescein sodium

Inactive Ingredients: Sodium hydroxide and/or hydrochloric acid (to adjust pH), and water for injection.



What does FLUORESCITE look like?



What are the available doses of FLUORESCITE?

Single use  5 mL vial containing 100 mg/mL fluorescein.

What should I talk to my health care provider before I take FLUORESCITE?

Caution should be exercised when fluorescein sodium is administered to a nursing woman.

How should I use FLUORESCITE?

FLUORESCITE Injection 10% is indicated in diagnostic fluorescein angiography or angioscopy of the retina and iris vasculature.

Adult Dose- The normal adult dose of FLUORESCITE Injection 10% (100 mg/mL) is 500 mg via intravenous administration.

For children, the dose should be calculated on the basis of 7.7 mg for each kg of actual body weight (or 35 mg for each 10 pounds of body weight) up to a maximum of 500 mg via intravenous administration.


What interacts with FLUORESCITE?

Sorry No Records found


What are the warnings of FLUORESCITE?

Sorry No Records found


What are the precautions of FLUORESCITE?

Sorry No Records found


What are the side effects of FLUORESCITE?

Sorry No records found


What should I look out for while using FLUORESCITE?

FLUORESCITE Injection 10% is contraindicated in patients with known hypersensitivity to fluorescein sodium or any other ingredients in this product. Rare cases of death due to anaphylaxis have been reported.

Fluorescein sodium can induce serious intolerance reactions. These reactions of intolerance are always unpredictable but they are more frequent in patients who have previously experienced an adverse reaction after fluorescein injection (symptoms other than nausea and vomiting) or in patients with history of allergy such as food or drug induced urticaria, asthma, eczema, allergic rhinitis.

Detailed questioning of each patient is recommended before the angiography to evaluate any prior history of allergy.


What might happen if I take too much FLUORESCITE?

Sorry No Records found


How should I store and handle FLUORESCITE?

Store at room temperature 20° to 25°C (68°to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature].Lovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1PediatricsLovastatin Tablets USP (white to off white round, unscored tablets) containing 20mg of lovastatin and engraved with “CTI 142”Bottle of 30 - 68788-9667-3Bottle of 60 - 68788-9667-6Bottle of 90 - 68788-9667-9Bottle of 100 - 68788-9667-1Lovastatin Tablets USP (white to off white round, unscored tablets) containing 40mg of lovastatin and engraved with “CTI 143”Bottle of 30 - 68788-9668-3Bottle of 60 - 68788-9668-6Bottle of 90 - 68788-9668-9Bottle of 100 - 68788-9668-1Pediatrics


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Fluorescein sodium responds to electromagnetic radiation and light between the wavelengths of 465-490 nm and fluoresces, i.e., emits light at wavelengths of 520-530 nm. Thus, the hydrocarbon is excited by blue light and emits light that appears yellowish-green. Following intravenous injection of fluorescein sodium in an aqueous solution, the unbound fraction of the fluorescein can be excited with a blue light flash from a fundus camera as it circulates through the ocular vasculature, and the yellowish green fluorescence of the dye is captured by the camera. In the fundus, the fluorescence of the dye demarcates the retinal and/or choroidal vasculature under observation, distinguishing it from adjacent areas/structures.

Non-Clinical Toxicology
FLUORESCITE Injection 10% is contraindicated in patients with known hypersensitivity to fluorescein sodium or any other ingredients in this product. Rare cases of death due to anaphylaxis have been reported.

Fluorescein sodium can induce serious intolerance reactions. These reactions of intolerance are always unpredictable but they are more frequent in patients who have previously experienced an adverse reaction after fluorescein injection (symptoms other than nausea and vomiting) or in patients with history of allergy such as food or drug induced urticaria, asthma, eczema, allergic rhinitis.

Detailed questioning of each patient is recommended before the angiography to evaluate any prior history of allergy.

Caution is to be exercised in patients with a history of allergy or bronchial asthma. An emergency tray should be available in the event of possible reaction to FLUORESCITE Injection 10%.

If a potential allergy is suspected, an intradermal skin test may be performed prior to intravenous administration, i.e., 0.05 mL injected intradermally to be evaluated 30 to 60 minutes following injection. Given the sensitivity and specificity of skin testing, a negative skin test is not proof that a patient is not allergic to fluorescein.

Skin and Urine Discoloration

Gastrointestinal Reactions

Hypersensitivity Reactions

[see and ].

Cardiopulmonary Reactions

Neurologic Reactions

Thrombophlebitis

[see and ].

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

Tips

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Interactions

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).