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gatifloxacin

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Overview

What is gatifloxacin?

Gatifloxacin sterile ophthalmic solution is an 8-methoxyfluoroquinolone anti-infective for the treatment of bacterial conjunctivitis. Its chemical name is (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, sesquihydrate. Its molecular formula is CHFNO 1½HO, and its molecular weight is 402.42. Its chemical structure is:

Gatifloxacin is a clear, pale yellow, sterile, preserved aqueous solution with an osmolality of 260-330 mOsm/kg and a pH of 5.1-5.7.

Gatifloxacin contains gatifloxacin 0.5% (5 mg/mL); benzalkonium chloride 0.005%; edetate disodium; purified water; and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.



What does gatifloxacin look like?



What are the available doses of gatifloxacin?

5 mL size bottle filled with 2.5 mL of gatifloxacin ophthalmic solution, 0.5%. ()

What should I talk to my health care provider before I take gatifloxacin?

How should I use gatifloxacin?

Gatifloxacin ophthalmic solution 0.5% solution is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms:

Aerobic Gram-Positive Bacteria:

Staphylococcus aureusStaphylococcus epidermidisStreptococcus mitis

*Streptococcus oralis*Streptococcus pneumoniae

Aerobic Gram-Negative Bacteria:

Haemophilus influenzae

*Efficacy for this organism was studied in fewer than 10 infections.

Patients 1 year of age or older: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times on Day 1. Instill one drop two to four times daily in the affected eye(s) while awake on Days 2 through 7.


What interacts with gatifloxacin?

Sorry No Records found


What are the warnings of gatifloxacin?

Sorry No Records found


What are the precautions of gatifloxacin?

Sorry No Records found


What are the side effects of gatifloxacin?

Sorry No records found


What should I look out for while using gatifloxacin?

None


What might happen if I take too much gatifloxacin?

Sorry No Records found


How should I store and handle gatifloxacin?

StorageStore at 20° to 25°C (68° to 77°F) excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. Protect from light and moisture. Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.StorageStore at 20° to 25°C (68° to 77°F) excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. Protect from light and moisture. Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.Gatifloxacin ophthalmic solution 0.5% is supplied sterile in a white, low density polyethylene (LDPE) bottle with a controlled dropper tip, and a tan, high impact polystyrene (HIPS) cap in the following size: 2.5 mL in 5 mL bottle: NDC 60758-615-25 Gatifloxacin ophthalmic solution 0.5% is supplied sterile in a white, low density polyethylene (LDPE) bottle with a controlled dropper tip, and a tan, high impact polystyrene (HIPS) cap in the following size: 2.5 mL in 5 mL bottle: NDC 60758-615-25


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Gatifloxacin is a fluoroquinolone antibacterial (see CLINICAL PHARMACOLOGY, ).

Non-Clinical Toxicology
None

The use of Fludarabine Phosphate for Injection, USP in combination with pentostatin is not recommended due to the risk of fatal pulmonary toxicity (see section).

Gatifloxacin solution should not be introduced directly into the anterior chamber of the eye.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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