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Gentamicin Sulfate

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Overview

What is Gentamicin Sulfate?

Gentamicin Sulfate Ointment is a wide spectrum antibiotic preparation for topical administration. Each gram contains 1.0 mg of Gentamicin in a base of White Petrolatum with Methylparaben and Propylparaben as preservatives.



What does Gentamicin Sulfate look like?



What are the available doses of Gentamicin Sulfate?

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What should I talk to my health care provider before I take Gentamicin Sulfate?

Sorry No records found

How should I use Gentamicin Sulfate?

Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum. Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial super-infections of fungal or viral infections. Please Note: Gentamicin sulfate is a bactericidal agent that is not effective against viruses or fungi in skin infections. Gentamicin sulfate is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria. Good results have been obtained in the treatment of infected stasis and other skin ulcers , infected superficial burns, paronychia, infected insect bites and stings, infected lacerations and abrasions, and wounds from minor surgery. Patients sensitive to neomycin can be treated with gentamicin sulfate, although regular observation of patients sensitive to topical antibiotics is advisable when such patients are treated with any topical antibiotic. Gentamicin Sulfate Ointment helps retain moisture and has been useful in infection on dry eczematous or psoriatic skin. Gentamicin Sulfate Ointment may be used in children over one year of age as well as in adults.

A small amount of Gentamicin Sulfate Ointment should be applied gently to the lesions three or four times daily. The area treated may be covered with a gauze dressing if desired. In impetigo contagiosa, the crusts should be removed before application of gentamicin sulfate to permit maximum contact between the antibiotic and the infection. Care should be exercised to avoid further contamination of the infected skin. Infected stasis ulcers have responded well to treatment with gentamicin sulfate under gelatin packing.


What interacts with Gentamicin Sulfate?

This drug product is contraindicated in individuals with a history of sensitivity to any of its components.



What are the warnings of Gentamicin Sulfate?

Sorry No Records found


What are the precautions of Gentamicin Sulfate?

The use of topical antibiotics occasionally allows overgrowth of nonsusceptible organisms, including fungi. If this condition occurs, or if irritation, sensitization or superinfection develops, treatment with gentamicin sulfate should be discontinued and appropriate therapy instituted.


What are the side effects of Gentamicin Sulfate?

In patients with dermatoses treated with gentamicin sulfate, irritation (erythema and pruritis) that did not usually require discontinuance of treatment has been reported in a small percentage of cases. There was no evidence of irritation or sensitization, however, in any of these patients patch-tested subsequently with gentamicin sulfate on normal skin. Possible photosensitization has been reported in several patients but could not be elicited in these patients by reapplication of gentamicin sulfate followed by exposure to ultraviolet radiation.


What should I look out for while using Gentamicin Sulfate?

This drug product is contraindicated in individuals with a history of sensitivity to any of its components.


What might happen if I take too much Gentamicin Sulfate?

Sorry No Records found


How should I store and handle Gentamicin Sulfate?

Store at 20°-25°C (68°-77°F) (see USP Controlled Room Temperature). Protect from light.Dispense in a tight, light-resistant container.Store at 20°-25°C (68°-77°F) (see USP Controlled Room Temperature). Protect from light.Dispense in a tight, light-resistant container.Gentamicin Sulfate Ointment USP, 0.1% is supplied in 15 gram tubes NDC 54868-6126-0.Store at controlled room temperature 15°-30°C (59°-86°F).E FOUGERA & COA division of Nycomed US Inc.Melville, New York 11747 USA I27815CR2/08#292Relabeling of "Additional Barcode" by:Physicians Total Care, Inc.Tulsa, OK       74146 Gentamicin Sulfate Ointment USP, 0.1% is supplied in 15 gram tubes NDC 54868-6126-0.Store at controlled room temperature 15°-30°C (59°-86°F).E FOUGERA & COA division of Nycomed US Inc.Melville, New York 11747 USA I27815CR2/08#292Relabeling of "Additional Barcode" by:Physicians Total Care, Inc.Tulsa, OK       74146 Gentamicin Sulfate Ointment USP, 0.1% is supplied in 15 gram tubes NDC 54868-6126-0.Store at controlled room temperature 15°-30°C (59°-86°F).E FOUGERA & COA division of Nycomed US Inc.Melville, New York 11747 USA I27815CR2/08#292Relabeling of "Additional Barcode" by:Physicians Total Care, Inc.Tulsa, OK       74146 Gentamicin Sulfate Ointment USP, 0.1% is supplied in 15 gram tubes NDC 54868-6126-0.Store at controlled room temperature 15°-30°C (59°-86°F).E FOUGERA & COA division of Nycomed US Inc.Melville, New York 11747 USA I27815CR2/08#292Relabeling of "Additional Barcode" by:Physicians Total Care, Inc.Tulsa, OK       74146 Gentamicin Sulfate Ointment USP, 0.1% is supplied in 15 gram tubes NDC 54868-6126-0.Store at controlled room temperature 15°-30°C (59°-86°F).E FOUGERA & COA division of Nycomed US Inc.Melville, New York 11747 USA I27815CR2/08#292Relabeling of "Additional Barcode" by:Physicians Total Care, Inc.Tulsa, OK       74146


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Gentamicin sulfate is a wide spectrum antibiotic that provides highly effective topical treatment in primary and secondary bacterial infections of the skin. Gentamicin Sulfate Ointment may clear infections that have not responded to treatment with other topical antibiotic agents. In primary skin infections such as impetigo contagiosa, treatment 3 or 4 times daily with Gentamicin Sulfate Ointment usually clears the lesions promptly. In secondary infections, Gentamicin Sulfate Ointment aids in the treatment of the underlying dermatoses by controlling the infection. Bacteria susceptible to the action of gentamicin sulfate include sensitive strains of (group A beta-hemolytic, alpha-hemolytic), (coagulase positive, coagulase negative, and some penicillinase-producing strains), and the gram-negative bacteria, , , , , and .

Non-Clinical Toxicology
This drug product is contraindicated in individuals with a history of sensitivity to any of its components.

Diphenhydramine hydrochloride has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc).

MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines.

The use of topical antibiotics occasionally allows overgrowth of nonsusceptible organisms, including fungi. If this condition occurs, or if irritation, sensitization or superinfection develops, treatment with gentamicin sulfate should be discontinued and appropriate therapy instituted.

In patients with dermatoses treated with gentamicin sulfate, irritation (erythema and pruritis) that did not usually require discontinuance of treatment has been reported in a small percentage of cases. There was no evidence of irritation or sensitization, however, in any of these patients patch-tested subsequently with gentamicin sulfate on normal skin. Possible photosensitization has been reported in several patients but could not be elicited in these patients by reapplication of gentamicin sulfate followed by exposure to ultraviolet radiation.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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