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GoLYTELY

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Overview

What is GoLYTELY?

For oral solution: Each 4 liter (4L) GoLYTELY jug contains a white powder for reconstitution. GoLYTELY is a combination of polyethylene glycol 3350, an osmotic laxative, and electrolytes (sodium sulfate, sodium chloride, sodium bicarbonate and potassium chloride) for oral solution.

Each 4 liter jug contains: polyethylene glycol 3350 236 g, sodium sulfate (anhydrous) 22.74 g, sodium bicarbonate 6.74 g, sodium chloride 5.86 g, potassium chloride 2.97 g. The solution is clear and colorless when reconstituted to a final volume of 4 liters with water.

Polyethylene Glycol 3350, NF

Sodium Sulfate, USP

The chemical name is NaSO. The average Molecular Weight is 142.04. The structural formula is:

Sodium Bicarbonate, USP

The chemical name is NaHCO. The average Molecular Weight is 84.01. The structural formula is:

Sodium Chloride, USP

The chemical name is NaCl. The average Molecular Weight: 58.44. The structural formula is:

Na Cl

Potassium Chloride, USP

The chemical name is KCl. The average Molecular Weight: 74.55. The structural formula is:

K-Cl



What does GoLYTELY look like?



What are the available doses of GoLYTELY?

For oral solution: polyethylene glycol 3350 236 grams, sodium sulfate (anhydrous) 22.74 grams, sodium bicarbonate 6.74 grams, sodium chloride 5.86 grams, potassium chloride 2.97 grams, and flavoring ingredients 3 grams; supplied in one 4 liter disposable jug ()

What should I talk to my health care provider before I take GoLYTELY?

How should I use GoLYTELY?

GoLYTELY is indicated for bowel cleansing prior to colonoscopy and barium enema X-ray examination in adults.

GoLYTELY, supplied as a powder, must be reconstituted with water before its use; it is not for direct ingestion . The 4 liter reconstituted GoLYTELY solution contains: 236 grams of polyethylene glycol (PEG) 3350, 22.74 grams sodium sulfate (anhydrous), 6.74 grams of sodium bicarbonate, 5.86 grams of sodium chloride, and 2.97 grams of potassium chloride. GoLYTELY is also available with pineapple flavor.


What interacts with GoLYTELY?

Sorry No Records found


What are the warnings of GoLYTELY?

Sorry No Records found


What are the precautions of GoLYTELY?

Sorry No Records found


What are the side effects of GoLYTELY?

Sorry No records found


What should I look out for while using GoLYTELY?

GoLYTELY is contraindicated in the following conditions:


What might happen if I take too much GoLYTELY?

Sorry No Records found


How should I store and handle GoLYTELY?

Storage:Store in sealed container at 59° to 86°F (15°C to 30°C). When reconstituted, keep solution refrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children. GoLYTELY                                   NDC 52268-100-01GoLYTELY Packet                       NDC 52268-700-01Pineapple Flavor GoLYTELY         NDC 52268-101-01 Storage:Store in sealed container at 59° to 86°F (15°C to 30°C). When reconstituted, keep solution refrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children. GoLYTELY                                   NDC 52268-100-01GoLYTELY Packet                       NDC 52268-700-01Pineapple Flavor GoLYTELY         NDC 52268-101-01 Storage:Store in sealed container at 59° to 86°F (15°C to 30°C). When reconstituted, keep solution refrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children. GoLYTELY                                   NDC 52268-100-01GoLYTELY Packet                       NDC 52268-700-01Pineapple Flavor GoLYTELY         NDC 52268-101-01 Storage:Store in sealed container at 59° to 86°F (15°C to 30°C). When reconstituted, keep solution refrigerated. Use within 48 hours, Discard unused portion. Keep out of reach of children. GoLYTELY                                   NDC 52268-100-01GoLYTELY Packet                       NDC 52268-700-01Pineapple Flavor GoLYTELY         NDC 52268-101-01 In powdered form, for oral administration as a solution following reconstitution. GoLYTELY is available in a disposable jug and a packet in powdered form containing: In powdered form, for oral administration as a solution following reconstitution. GoLYTELY is available in a disposable jug and a packet in powdered form containing:


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

The primary mode of action is thought to be through the osmotic effect of polyethylene glycol 3350 which causes water to be retained in the colon and produces a watery stool.

Non-Clinical Toxicology
GoLYTELY is contraindicated in the following conditions:

Specific drug interaction studies have not been conducted with ophthalmic ciprofloxacin. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance the effects of the oral anticoagulant, warfarin, and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly.

see Drug Interactions

The following adverse reactions have been identified during post-approval use of GoLYTELY. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Nausea, abdominal fullness and bloating are the most common adverse reactions (occurred in up to 50% of patients) to administration of GoLYTELY. Abdominal cramps, vomiting and anal irritation occur less frequently. These adverse reactions are transient and usually subside rapidly. Isolated cases of urticaria, rhinorrhea, dermatitis and (rarely) anaphylactic reaction have been reported which may represent allergic reactions.

Published literature contains isolated reports of serious adverse reactions following the administration of PEG-electrolyte solution products in patients over 60 years of age. These adverse events include upper GI bleeding from Mallory-Weiss Tear, esophageal perforation, asystole, sudden dyspnea with pulmonary edema, and “butterfly-like” infiltrates on chest X-ray after vomiting and aspirating PEG.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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