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Guaifenesin
Overview
What is Guaifenesin?
Guaifenesin (glyceryl guaiacolate) has the chemical name 3-(2-methoxyphenoxy)-1,2-propanediol. Its molecular formula is CHO with a molecular weight of 198.21. It is a white or slightly gray crystalline substance with a slightly bitter aromatic taste. One gram dissolves in 20 mL water at 25°C; it is freely soluble in ethanol. Guaifenesin is readily absorbed from the GI tract and is rapidly metabolized and excreted in the urine. Guaifenesin has a plasma half-life of one hour. The major urinary metabolite is β-(2-methoxyphenoxy) lactic acid.
Guaifenesin is an expectorant available for oral administration as:
Tablets —
Other ingredients:
What does Guaifenesin look like?
What are the available doses of Guaifenesin?
Sorry No records found.
What should I talk to my health care provider before I take Guaifenesin?
Sorry No records found
How should I use Guaifenesin?
Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus, drain bronchial tubes and make coughs more productive. Helps loosen phlegm and thin bronchial secretions in patients with stable chronic bronchitis.
Adults and children 12 years of age and older:
PATIENTS SHOULD BE ADVISED TO KEEP THESE AND ALL DRUGS OUT OF THE REACH OF CHILDREN AND TO SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY IN CASE OF ACCIDENTAL OVERDOSE.
What interacts with Guaifenesin?
Hypersensitivity to any of the ingredients.
What are the warnings of Guaifenesin?
Sorry No Records found
What are the precautions of Guaifenesin?
Carcinogenesis, Mutagenesis, Impairment of Fertility:
Pregnancy:
Teratogenic Effects—Pregnancy Category C:
Nursing Mothers:
Laboratory Test Interactions:
What are the side effects of Guaifenesin?
To report SUSPECTED ADVERSE REACTIONS, contact FDA at 1-800-FDA-1088 or .
Guaifenesin
What should I look out for while using Guaifenesin?
Hypersensitivity to any of the ingredients.
What might happen if I take too much Guaifenesin?
In massive overdosage the stomach should be emptied (emesis and/or gastric lavage) and further absorption prevented. Treatment is symptomatic and supportive.
The acute toxicity of is low and overdosage is unlikely to produce serious toxic effects. In laboratory animals no toxicity resulted when guaifenesin was administered by stomach tube in doses up to 5 grams/kg.
How should I store and handle Guaifenesin?
Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].Keep out of reach of children.Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].Keep out of reach of children.GuaifenesinTabletsGuaifenesinTablets
Clinical Information
Chemical Structure
No Image foundClinical Pharmacology
Guaifenesin is an expectorant, the action of which promotes or facilitates the removal of secretions from the respiratory tract. By increasing sputum volume and making sputum less viscous, guaifenesin facilitates expectoration of retained secretions.
Non-Clinical Toxicology
Hypersensitivity to any of the ingredients.As adapalene cream has the potential to produce local irritation in some patients, concomitant use of other potentially irritating topical products (medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices or lime rind) should be approached with caution. Particular caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid in combination with adapalene cream. If these preparations have been used, it is advisable not to start therapy with adapalene cream until the effects of such preparations in the skin have subsided.
Carcinogenesis, Mutagenesis, Impairment of Fertility:
To report SUSPECTED ADVERSE REACTIONS, contact FDA at 1-800-FDA-1088 or .
Guaifenesin
Reference
This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"
While we update our database periodically, we cannot guarantee it is always updated to the latest version.
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