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Horizant

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Overview

What is Horizant?

HORIZANT (gabapentin enacarbil) is a prodrug of gabapentin. Gabapentin enacarbil is described as (1-{[({(1)-1-[(2-Methylpropanoyl)oxy]ethoxy}carbonyl)amino]methyl} cyclohexyl) acetic acid. It has a molecular formula of CHNOand a molecular weight of 329.39. It is a racemate and has the following structural formula:

Gabapentin enacarbil is a white to off-white crystalline solid with a melting onset of approximately 64°C and a solubility of 0.5 mg/mL in water and 10.2 mg/mL in phosphate buffer (pH 6.3).

HORIZANT is administered orally. Each HORIZANT Extended-Release Tablet contains 300 mg or 600 mg of gabapentin enacarbil and the following inactive ingredients: colloidal silicon dioxide, dibasic calcium phosphate dihydrate, glyceryl behenate, magnesium stearate, sodium lauryl sulfate, and talc.



What does Horizant look like?



What are the available doses of Horizant?

Extended-Release Tablets: 300 mg and 600 mg. ()

What should I talk to my health care provider before I take Horizant?

Pregnancy: Based on animal data, may cause fetal harm. ()

How should I use Horizant?

HORIZANT(gabapentin enacarbil) Extended-Release Tablets are indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS) in adults.

HORIZANT is not recommended for patients who are required to sleep during the daytime and remain awake at night.

Tablets should be swallowed whole and should not be cut, crushed, or chewed.

Tablets should be taken with food.

HORIZANT is not interchangeable with other gabapentin products because of differing pharmacokinetic profiles.


What interacts with Horizant?

Sorry No Records found


What are the warnings of Horizant?

Sorry No Records found


What are the precautions of Horizant?

Sorry No Records found


What are the side effects of Horizant?

Sorry No records found


What should I look out for while using Horizant?

None.


What might happen if I take too much Horizant?


How should I store and handle Horizant?

HORIZANT Extended-Release Tablets containing 300 mg of gabapentin enacarbil are white to off-white, with occasional black/grey spots, oval-shaped tablets debossed with "GS TF7".HORIZANT Extended-Release Tablets containing 600 mg of gabapentin enacarbil are white to off-white, with occasional black/grey spots, oval-shaped tablets debossed with "GS LFG". They are supplied as follows:HORIZANT Extended-Release Tablets containing 300 mg of gabapentin enacarbil are white to off-white, with occasional black/grey spots, oval-shaped tablets debossed with "GS TF7".HORIZANT Extended-Release Tablets containing 600 mg of gabapentin enacarbil are white to off-white, with occasional black/grey spots, oval-shaped tablets debossed with "GS LFG". They are supplied as follows: