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Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%

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Overview

What is Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

Each gram contains 20 mg of hydrocortisone acetate, 10 mg of iodoquinol and 10 mg of aloe polysaccharide in a vehicle consisting of: amino methylpropanol 95%, benzyl alcohol, carbomer, citric acid anhydrous, D&C yellow #10, FD&C blue #1, glycerin, glyceryl polymethacrylate, magnesium aluminum silicate, palmitoyl oligopeptide, PPG-20 methyl glucose ether, propylene glycol, purified water and SD Alcohol 40B.

 Hydrocortisone acetate is an anti-inflammatory and antipruritic agent. Chemically, hydrocortisone acetate is [Pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11, 17-dihydroxy-, (11-ß)-] with the molecular formula (C23H32O6) and is represented by the following structural formula:

Iodoquinol is an antifungal and antibacterial agent. Chemically, Iodoquinol is [5,7-diiodo-8-quinolinol] with the molecular formula (C9H5I2NO) and is represented by the following structural formula:

Aloe Polysaccharides are a concentrated, water soluble subcomponent of Aloe Vera with a mono-sugar ratio of Man : Gal : Glc: 40 : 1.4 : 1.0, linkage of 1-4 ß - linkage, O-Acetyl group of 25% of sugar units, and specific rotation of [α]D= -3.98˚ at 23.2˚ C. Average molecular weight is 80,000 daltons. Chemically, Aloe Polysaccharides is represented by the following structural formula:



What does Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% look like?



What are the available doses of Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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What should I talk to my health care provider before I take Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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How should I use Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

Based on a review of a related drug by the National Research Council and subsequent FDA classification for that drug, the indications are as follows: “Possibly” Effective: Contact or atopic dermatitis; impetiginized eczema; nummular eczema; endogenous chronic infectious dermatitis; stasis dermatitis; pyoderma; nuchal eczema and chronic eczematoid otitis externa; acne urticata; localized or disseminated neurodermatitis; lichen simplex chronicus; anogenital pruritus (vulvae, scroti, ani); folliculitis; bacterial dermatoses; mycotic dermatoses such as tinea (capitis, cruris, corporis, pedis); monliasis; intertrigo. Final classification of the less-than-effective indications requires further investigation.

Apply to affected area(s) three to four times per day or as directed by a physician. Follow your physician’s directions regarding length of treatment after symptoms resolve.


What interacts with Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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What are the warnings of Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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What are the precautions of Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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What are the side effects of Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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What should I look out for while using Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.


What might happen if I take too much Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

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How should I store and handle Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%?

Store at 25°C (77°F); excursions permitted to 15 to 30°C (59 to 86°F) [see USP Controlled Room Temperature]. Pharmacist: Dispense in a tight, light-resistant container with a child-resistant closure and medication guide. Store at 25°C (77°F); excursions permitted to 15 to 30°C (59 to 86°F) [see USP Controlled Room Temperature]. Pharmacist: Dispense in a tight, light-resistant container with a child-resistant closure and medication guide. This product is supplied in the following size(s):48 g Tube, NDC 13925-174-48This product is supplied in the following size(s):48 g Tube, NDC 13925-174-48


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Hydrocortisone acetate has anti-inflammatory, antipruritic and vasoconstrictive properties. While the mechanism of anti-inflammatory activity is unclear, there is evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in humans. Iodoquinol has both antifungal and antibacterial properties.

Non-Clinical Toxicology
This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.

WARNINGS: KEEP OUT OF REACH OF CHILDREN. PRECAUTIONS: FOR EXTERNAL USE ONLY. NOT 

​FOR OPHTHALMIC USE.

The following local adverse reactions are reported infrequently with topical corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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