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ciclopirox

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Overview

What is Loprox?

LOPROX (ciclopirox) Shampoo 1% contains the synthetic antifungal agent ciclopirox for topical use.

Each gram (equivalent to 0.96 mL) of LOPROX Shampoo contains 10 mg ciclopirox in a shampoo base consisting of disodium laureth sulfosuccinate, laureth-2, purified water, sodium chloride, and sodium laureth sulfate.

LOPROX Shampoo is a colorless, translucent solution. The chemical name for ciclopirox is 6-cyclohexyl-1-hydroxy-4-methyl-2(1)-pyridone, with the empirical formula CHNO and a molecular weight of 207.27. The CAS Registry Number is [29342-05-0]. The chemical structure is:



What does Loprox look like?



What are the available doses of Loprox?

LOPROX is a shampoo containing 1% ciclopirox.

Each gram (equivalent to 0.96 mL) of LOPROX Shampoo contains 10 mg ciclopirox in a colorless and translucent shampoo base.

What should I talk to my health care provider before I take Loprox?

How should I use Loprox?

LOPROX Shampoo is indicated for the topical treatment of seborrheic dermatitis of the scalp in adults.

LOPROX Shampoo is not for ophthalmic, oral, or intravaginal use.

Wet hair and apply approximately 1 teaspoon (5 mL) of LOPROX Shampoo to the scalp. Up to 2 teaspoons (10 mL) may be used for long hair. Lather and leave on hair and scalp for 3 minutes. A timer may be used. Avoid contact with eyes. Rinse off. Treatment should be repeated twice per week for 4 weeks, with a minimum of 3 days between applications.

If a patient with seborrheic dermatitis shows no clinical improvement after 4 weeks of treatment with LOPROX Shampoo, the diagnosis should be reviewed.


What interacts with Loprox?

Sorry No Records found


What are the warnings of Loprox?

Sorry No Records found


What are the precautions of Loprox?

Sorry No Records found


What are the side effects of Loprox?

Sorry No records found


What should I look out for while using Loprox?

None.


What might happen if I take too much Loprox?

Sorry No Records found


How should I store and handle Loprox?

Pre-filled dual chamber syringe:Store below 30°C [86°F]. Do not freeze. Protect the syringe from light by storing in the original package until time of use. Vial:Store at 25°C (77°F), excursions permitted between 15°C and 30°C (59°F to 86°F) [see USP Controlled Room Temperature].Pre-filled dual chamber syringe:Store below 30°C [86°F]. Do not freeze. Protect the syringe from light by storing in the original package until time of use. Vial:Store at 25°C (77°F), excursions permitted between 15°C and 30°C (59°F to 86°F) [see USP Controlled Room Temperature].Pre-filled dual chamber syringe:Store below 30°C [86°F]. Do not freeze. Protect the syringe from light by storing in the original package until time of use. Vial:Store at 25°C (77°F), excursions permitted between 15°C and 30°C (59°F to 86°F) [see USP Controlled Room Temperature].Pre-filled dual chamber syringe:Store below 30°C [86°F]. Do not freeze. Protect the syringe from light by storing in the original package until time of use. Vial:Store at 25°C (77°F), excursions permitted between 15°C and 30°C (59°F to 86°F) [see USP Controlled Room Temperature].LOPROX (ciclopirox) Shampoo 1% is colorless and translucent, and supplied in 120 mL plastic bottles(NDC 99207-010-10).Discard unused product after initial treatment duration.LOPROX (ciclopirox) Shampoo 1% is colorless and translucent, and supplied in 120 mL plastic bottles(NDC 99207-010-10).Discard unused product after initial treatment duration.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Ciclopirox is a hydroxypyridone antifungal agent although the relevance of this property for the indication of seborrheic dermatitis is not known. Ciclopirox acts by chelation of polyvalent cations (Fe or Al), resulting in the inhibition of the metal-dependent enzymes that are responsible for the degradation of peroxides within the fungal cell.

Non-Clinical Toxicology
None.

There is evidence that the anticonvulsant action of phenytoin is antagonized by folic acid. A patient whose epilepsy is completely controlled by phenytoin may require increased doses to prevent convulsions if folic acid is given.

Folate deficiency may result from increased loss of folate, as in renal dialysis and/or interference with metabolism (e.g., folic acid antagonists such as methotrexate); the administration of anticonvulsants, such as diphenylhydantoin, primidone, and barbiturates; alcohol consumption and, especially, alcoholic cirrhosis; and the administration of pyrimethamine and nitrofurantoin.

False low serum and red cell folate levels may occur if the patient has been taking antibiotics, such as tetracycline, which suppress the growth of .

If a reaction suggesting sensitivity or irritation occurs with the use of LOPROX Shampoo, treatment should be discontinued and appropriate therapy instituted.

Contact of LOPROX Shampoo with the eyes should be avoided. If contact occurs, rinse thoroughly with water.

In patients with lighter hair color, hair discoloration has been reported.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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