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Malathion

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Overview

What is Malathion?

Malathion Lotion contains 0.005 g of malathion per mL in a vehicle of isopropyl alcohol (78%), terpineol, dipentene, and pine needle oil. The chemical name of malathion is (±) - [(dimethoxyphosphinothioyl) - thio] butanedioic acid diethyl ester. Malathion has a molecular weight of 330.36, represented by CHOPS, and has the following chemical structure:



What does Malathion look like?



What are the available doses of Malathion?

Sorry No records found.

What should I talk to my health care provider before I take Malathion?

Sorry No records found

How should I use Malathion?

Malathion Lotion is indicated for patients infected with (head lice and their ova) of the scalp hair.

Further treatment is generally not necessary. Other family members should be evaluated by a physician to determine if infested, and if so, receive treatment.


What interacts with Malathion?

Malathion Lotion is contraindicated for neonates and infants because their scalps are more permeable and may have increased absorption of malathion. Malathion Lotion should also not be used on individuals known to be sensitive to malathion or any of the ingredients in the vehicle.



What are the warnings of Malathion?

  • Malathion Lotion is . The lotion and wet hair should not be exposed to open flames or electric heat sources, including hair dryers and electric curlers. Do not smoke while applying lotion or while hair is wet. Allow hair to dry naturally and to remain uncovered after application of Malathion Lotion.
  • Malathion Lotion should only be used on children under the direct supervision of an adult.
  • If Malathion Lotion comes into contact with the eyes, flush immediately with water. Consult a physician if eye irritation persists.
  • If skin irritation occurs, discontinue use of product until irritation clears. Reapply the Malathion Lotion, and if irritation reoccurs, consult a physician.
  • Slight stinging sensations may occur with the use of Malathion Lotion.



What are the precautions of Malathion?

Sorry No Records found


What are the side effects of Malathion?

Malathion has been shown to be irritating to the skin and scalp. Accidental contact with the eyes can result in mild conjunctivitis. It is not known if Malathion Lotion has the potential to cause contact allergic sensitization.


What should I look out for while using Malathion?

Malathion Lotion is contraindicated for neonates and infants because their scalps are more permeable and may have increased absorption of malathion. Malathion Lotion should also not be used on individuals known to be sensitive to malathion or any of the ingredients in the vehicle.


What might happen if I take too much Malathion?

Consideration should be given, as part of the treatment program, to the high concentration of isopropyl alcohol in the vehicle.

Malathion, although a weaker cholinesterase inhibitor than some other organophosphates, may be expected to exhibit the same symptoms of cholinesterase depletion after accidental ingestion orally. If accidentally swallowed, vomiting should be induced promptly or the stomach lavaged with 5% sodium bicarbonate solution.

Severe respiratory distress is the major and most serious symptom of organophosphate poisoning requiring artificial respiration, and atropine may be needed to counteract the symptoms of cholinesterase depletion.

Repeat analyses of serum and RBC cholinesterase may assist in establishing the diagnosis and formulating a long-range prognosis.


How should I store and handle Malathion?

Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP] .Malathion Lotion, USP 0.5%, is supplied in bottles of 2 fl. oz. (59 mL) NDC 42043-150-23. Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP]. Flammable. Keep away from heat and open flame.Malathion Lotion, USP 0.5%, is supplied in bottles of 2 fl. oz. (59 mL) NDC 42043-150-23. Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP]. Flammable. Keep away from heat and open flame.Malathion Lotion, USP 0.5%, is supplied in bottles of 2 fl. oz. (59 mL) NDC 42043-150-23. Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP]. Flammable. Keep away from heat and open flame.


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Clinical Information

Chemical Structure

No Image found
Clinical Pharmacology

Malathion is an organophosphate agent which acts as a pediculicide by inhibiting cholinesterase activity in vivo. Inadvertent transdermal absorption of malathion has occurred from its agricultural use. In such cases, acute toxicity was manifested by excessive cholinergic activity, i.e., increased sweating, salivary and gastric secretion, gastrointestinal and uterine motility, and bradycardia (see  ). Because the potential for transdermal absorption of malathion from Malathion Lotion is not known at this time, strict adherence to the dosing instructions regarding its use in children, method of application, duration of exposure, and frequency of application is required.

Non-Clinical Toxicology
Malathion Lotion is contraindicated for neonates and infants because their scalps are more permeable and may have increased absorption of malathion. Malathion Lotion should also not be used on individuals known to be sensitive to malathion or any of the ingredients in the vehicle.

Malathion has been shown to be irritating to the skin and scalp. Accidental contact with the eyes can result in mild conjunctivitis. It is not known if Malathion Lotion has the potential to cause contact allergic sensitization.

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Interactions

Interactions

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