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Moxifloxacin

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Overview

What is Moxifloxacin?

Moxifloxacin hydrochloride USP is a synthetic broad spectrum antibacterial agent for oral administration. Moxifloxacin, a fluoroquinolone, is available as the monohydrochloride salt of 1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3 quinoline carboxylic acid. It is a slightly yellow to yellow powder or crystals with a molecular weight of 437.9. Its molecular formula is CHFNO*HCl and its chemical structure is as follows



What does Moxifloxacin look like?



What are the available doses of Moxifloxacin?

Moxifloxacin hydrochloride tablets 400 mg are available as Beige colored, capsule shaped, biconvex tablets debossed ‘112’ on one side and plain on other side.

What should I talk to my health care provider before I take Moxifloxacin?

How should I use Moxifloxacin?


What interacts with Moxifloxacin?

Sorry No Records found


What are the warnings of Moxifloxacin?

Sorry No Records found


What are the precautions of Moxifloxacin?

Sorry No Records found


What are the side effects of Moxifloxacin?

Sorry No records found


What should I look out for while using Moxifloxacin?

Moxifloxacin hydrochloride tablets are contraindicated in persons with a history of hypersensitivity to moxifloxacin or any member of the quinolone class of antibacterials [see ]. 

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Discontinue moxifloxacin, immediately and avoid the use of fluoroquinolones, including moxifloxacin, in patients who experience any of these serious adverse reactions

[see Warnings and Precautions ()]

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Fluoroquinolones, including moxifloxacin,, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid moxifloxacin, in patients with known history of myasthenia gravis

[see Warnings and Precautions ()].

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• Acute bacterial exacerbation of chronic bronchitis

[see Indications and Usage ()]

Drug Interactions

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WARNINGS


What might happen if I take too much Moxifloxacin?

Single oral overdoses up to 2.8 g were not associated with any serious adverse events. In the event of acute overdose, empty the stomach and maintain adequate hydration. Monitor ECG due to the possibility of QT interval prolongation. Carefully observe the patient and give supportive treatment. The administration of activated charcoal as soon as possible after oral overdose may prevent excessive increase of systemic moxifloxacin exposure. About 3% and 9% of the dose of moxifloxacin, as well as about 2% and 4.5% of its glucuronide metabolite are removed by continuous ambulatory peritoneal dialysis and hemodialysis, respectively. 


How should I store and handle Moxifloxacin?

Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP].


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Clinical Information

Chemical Structure

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Clinical Pharmacology

Moxifloxacin is a member of the flouroquinolone class of antibacterial agents [see ].

Non-Clinical Toxicology
Moxifloxacin hydrochloride tablets are contraindicated in persons with a history of hypersensitivity to moxifloxacin or any member of the quinolone class of antibacterials [see ]. 

•

•

•

•  

Discontinue moxifloxacin, immediately and avoid the use of fluoroquinolones, including moxifloxacin, in patients who experience any of these serious adverse reactions

[see Warnings and Precautions ()]

.

Fluoroquinolones, including moxifloxacin,, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid moxifloxacin, in patients with known history of myasthenia gravis

[see Warnings and Precautions ()].

• -

•

• Acute bacterial exacerbation of chronic bronchitis

[see Indications and Usage ()]

Array

The following serious and otherwise important adverse reactions are discussed in greater detail in the warnings and precautions section of the label:

• Disabling and Potentially Irreversible Serious Adverse Reactions Including Tendinitis and Tendon Rupture, Peripheral Neuropathy, and Central Nervous System Effects [see

• Tendinitis and Tendon Rupture[see ]

• Peripheral Neuropathy [see ]

• Central Nervous System Effects [see ]

• Exacerbation of Myasthenia Gravis [see ]

• QT Prolongation [see ]

• Other Serious and Sometimes Fatal Adverse Reactions [see ]

• Hypersensitivity Reactions [see ]

• Clostridium difficile-Associated Diarrhea [see ]

• Blood Glucose Disturbances [see ]

• Photosensitivity/Phototoxicity [see ]

• Development of Drug Resistant Bacteria [see ]

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Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

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Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72
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Tips

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Interactions

Interactions

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