Moxifloxacin Hydrochloride

×

Overview

What is Moxifloxacin Hydrochloride?

Moxifloxacin Hydrochloride (moxifloxacin hydrochloride) is a synthetic antibacterial agent for oral and intravenous administration. Moxifloxacin, a fluoroquinolone, is available as the monohydrochloride salt of 1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3 quinoline carboxylic acid. It is a slightly yellow to yellow crystalline substance with a molecular weight of 437.9. Its empirical formula is C H FN O HCl and its chemical structure is as follows:

What does Moxifloxacin Hydrochloride look like?

What are the available doses of Moxifloxacin Hydrochloride?

Oblong, dull red, film-coated tablets imprinted with “BAYER” on one side and “M400” on the other containing moxifloxacin hydrochloride (equivalent to 400 mg moxifloxacin).

What should I talk to my health care provider before I take Moxifloxacin Hydrochloride?

How should I use Moxifloxacin Hydrochloride?

Moxifloxacin Hydrochloride is indicated in adult patients for the treatment of Community Acquired Pneumonia caused by susceptible isolates of (including multi-drug resistant [MDRSP]) methicillin-susceptible or .

MDRSP isolates are isolates resistant to two or more of the following antibacterial drugs: penicillin (minimum inhibitory concentrations [MIC] ≥ 2 mcg/mL), 2nd generation cephalosporins (for example, cefuroxime), macrolides, tetracyclines, and trimethoprim/sulfamethoxazole.

The dose of Moxifloxacin Hydrochloride is 400 mg (orally or as an intravenous infusion) once every 24 hours. The duration of therapy depends on the type of infection as described in Table 1.The dose of Moxifloxacin Hydrochloride is 400 mg (orally or as an intravenous infusion) once every 24 hours. The duration of therapy depends on the type of infection as described in Table 1.

What interacts with Moxifloxacin Hydrochloride?

Sorry No Records found

What are the warnings of Moxifloxacin Hydrochloride?

Sorry No Records found

What are the precautions of Moxifloxacin Hydrochloride?

Sorry No Records found

What are the side effects of Moxifloxacin Hydrochloride?

Sorry No records found

What should I look out for while using Moxifloxacin Hydrochloride?

Moxifloxacin Hydrochloride is contraindicated in persons with a history of hypersensitivity to moxifloxacin or any member of the quinolone class of antibacterials .

What might happen if I take too much Moxifloxacin Hydrochloride?

Single oral overdoses up to 2.8 g were not associated with any serious adverse events. In the event of acute overdose, Empty the stomach and maintain adequate hydration. Monitor ECG due to the possibility of QT interval prolongation. Carefully observe the patient and give supportive treatment. The administration of activated charcoal as soon as possible after oral overdose may prevent excessive increase of systemic moxifloxacin exposure. About 3% and 9% of the dose of moxifloxacin, as well as about 2% and 4.5% of its glucuronide metabolite are removed by continuous ambulatory peritoneal dialysis and hemodialysis, respectively.

How should I store and handle Moxifloxacin Hydrochloride?

Unopened vials of gemcitabine for injection, USP are stable until the expiration date indicated on the package when stored at controlled room temperature 20° to 25°C (68° to 77°F) and that allows for excursions between 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature] [].Moxifloxacin Hydrochloride (moxifloxacin hydrochloride) tablets are available as oblong, dull red film-coated tablets containing 400 mg moxifloxacin.The tablet is coded with the word “BAYER” on one side and “M400” on the reverse side. Bottles of 5: NDC 43063-585-05 Bottles of 10: NDC 43063-585-10Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) . Avoid high humidity. Moxifloxacin Hydrochloride (moxifloxacin hydrochloride) tablets are available as oblong, dull red film-coated tablets containing 400 mg moxifloxacin.The tablet is coded with the word “BAYER” on one side and “M400” on the reverse side. Bottles of 5: NDC 43063-585-05 Bottles of 10: NDC 43063-585-10Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) . Avoid high humidity. Moxifloxacin Hydrochloride (moxifloxacin hydrochloride) tablets are available as oblong, dull red film-coated tablets containing 400 mg moxifloxacin.The tablet is coded with the word “BAYER” on one side and “M400” on the reverse side. Bottles of 5: NDC 43063-585-05 Bottles of 10: NDC 43063-585-10Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) . Avoid high humidity. Moxifloxacin Hydrochloride (moxifloxacin hydrochloride) tablets are available as oblong, dull red film-coated tablets containing 400 mg moxifloxacin.The tablet is coded with the word “BAYER” on one side and “M400” on the reverse side. Bottles of 5: NDC 43063-585-05 Bottles of 10: NDC 43063-585-10Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) . Avoid high humidity. Moxifloxacin Hydrochloride (moxifloxacin hydrochloride) tablets are available as oblong, dull red film-coated tablets containing 400 mg moxifloxacin.The tablet is coded with the word “BAYER” on one side and “M400” on the reverse side. Bottles of 5: NDC 43063-585-05 Bottles of 10: NDC 43063-585-10Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F) . Avoid high humidity.

×

Clinical Information

Chemical Structure

No Image found

Clinical Pharmacology

Moxifloxacin Hydrochloride is a member of the fluoroquinolone class of antibacterial agents

Non-Clinical Toxicology

Moxifloxacin Hydrochloride is contraindicated in persons with a history of hypersensitivity to moxifloxacin or any member of the quinolone class of antibacterials .

In obstetrics, if vasopressor drugs are used to correct hypotension or are added to a local anesthetic solution, some oxytocic drugs may cause severe persistent hypertension and may even cause rupture of a cerebral blood vessel to occur during the postpartum period.

Fluoroquinolones, including Moxifloxacin Hydrochloride, have been associated with disabling and potentially irreversible serious adverse reactions from different body systems that can occur together in the same patient. Commonly seen adverse reactions include tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system effects (hallucinations, anxiety, depression, insomnia, severe headaches, and confusion). These reactions can occur within hours to weeks after starting Moxifloxacin Hydrochloride. Patients of any age or without pre-existing risk factors have experienced these adverse reactions [see Warnings and Precautions ( , , )].

Discontinue Moxifloxacin Hydrochloride immediately at the first signs or symptoms of any serious adverse reaction. In addition, avoid the use of fluoroquinolones, including Moxifloxacin Hydrochloride, in patients who have experienced any of these serious adverse reactions associated with fluoroquinolones.

The following serious and otherwise important adverse reactions are discussed in greater detail in the warnings and precautions section of the label:

×

Reference

This information is obtained from the National Institute of Health's Standard Packaging Label drug database.
"https://dailymed.nlm.nih.gov/dailymed/"

While we update our database periodically, we cannot guarantee it is always updated to the latest version.

×

Review

×

Professional

Clonazepam Description Each single-scored tablet, for oral administration, contains 0.5 mg, 1 mg, or 2 mg Clonazepam, USP, a benzodiazepine. Each tablet also contains corn starch, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and povidone. Clonazepam tablets USP 0.5 mg contain Yellow D&C No. 10 Aluminum Lake. Clonazepam tablets USP 1 mg contain Yellow D&C No. 10 Aluminum Lake, as well as FD&C Blue No. 1 Aluminum Lake. Chemically, Clonazepam, USP is 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one. It is a light yellow crystalline powder. It has the following structural formula: C15H10ClN3O3 M.W. 315.72

×

Tips

×

Interactions

A total of 440 drugs (1549 brand and generic names) are known to interact with Imbruvica (ibrutinib). 228 major drug interactions (854 brand and generic names) 210 moderate drug interactions (691 brand and generic names) 2 minor drug interactions (4 brand and generic names) Show all medications in the database that may interact with Imbruvica (ibrutinib).

Disclaimer: